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A kidney transplant is an operation where a healthy kidney from one person (the donor) is transferred to a person who has little or no kidney function (the recipient).
Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States. [More]
Hyde Park artist draws daily creative inspiration from chronic health experience

Hyde Park artist draws daily creative inspiration from chronic health experience

A kidney transplantation means much more than good health to Jason E. Jones. The 53 year-old Hyde Park artist and Loyola Medicine patient draws daily creative inspiration from his chronic health experience. [More]
Kidney transplant recipients with inflammation prior to surgery more likely to develop diabetes

Kidney transplant recipients with inflammation prior to surgery more likely to develop diabetes

Up to 30 percent of people who receive organ transplants will develop diabetes, but researchers are unsure why. Although doctors typically blame immunosuppressive drugs that transplant recipients take to prevent organ rejection, it's unclear why some people develop the lifelong disorder, while others do not. [More]
Carfilzomib therapy shows promise for pre-kidney transplant patients

Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates. [More]
Eculizumab drug provides new hope for kidney failure patients

Eculizumab drug provides new hope for kidney failure patients

Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type. [More]
'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

Investigators have uncovered a "weekend effect" contributing to the worsening availability of donor kidneys in the United States. They found that kidneys that would normally be made available for transplantation were less likely to be procured from donors over the weekend (89.5% on the weekend vs. 90.2% during the week). [More]
Safety tips to prevent slips and falls among seniors

Safety tips to prevent slips and falls among seniors

May is National Trauma Awareness Month, and this year the American Trauma Society is raising awareness about senior safety and falls with "Safe Steps for Seniors." The Stony Brook Trauma Center is taking steps to shed light on the matter to help prevent serious injuries from occurring. [More]
Study shows women may face decreased kidney damage from ischemia reperfusion injury

Study shows women may face decreased kidney damage from ischemia reperfusion injury

After a kidney transplant, women may experience decreased kidney damage from ischemia reperfusion injury compared to men due to the impact of gender-specific hormones, suggests a new preclinical study and an analysis of patient data published online in the Journal of Clinical Investigation from researchers at the Perelman School of Medicine at the University of Pennsylvania. [More]
Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

In a new study, published in the online edition of the journal EBioMedicine, a multi-disciplinary team led by researchers at University of California, San Diego School of Medicine has identified key inflammatory mechanisms underlying type 1 diabetes and obesity-related kidney dysfunction. [More]
HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant. [More]
Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen. [More]
New procedure allows kidney transplants from incompatible donors

New procedure allows kidney transplants from incompatible donors

Researchers have found a way to stop patients rejecting kidneys that have come from incompatible donors, potentially slashing the waiting time for thousands of people in desperate need of the procedure. [More]
EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

On World Kidney Day, leading experts from the European ADPKD Forum today issue a collaborative letter to over 350 European decision makers (European Parliament, European Commission, Council representatives) celebrating the year one progress of the Brussels Declaration on ADPKD, while calling for urgent backing from policy makers to reduce the widespread inequalities and variations in care that remain. [More]
Pioneering progress on ADPKD: an interview with Tess Harris

Pioneering progress on ADPKD: an interview with Tess Harris

ADPKD is a chronic, progressive and inherited kidney disease characterized by fluid-filled cysts that develop in the kidneys and other organs. It is the most common inherited kidney disease, and affects millions worldwide. [More]
MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare Health System announced today that it has entered into a joint venture partnership with Fresenius Medical Care North America to operate 15 dialysis clinics in Orange and Los Angeles counties. Thirteen of these clinics are fully operational and two additional clinics are being developed in San Juan Capistrano and Huntington Beach. [More]
Vanderbilt nephrologist building implantable artificial kidney with microchip filters

Vanderbilt nephrologist building implantable artificial kidney with microchip filters

Vanderbilt University Medical Center nephrologist and associate professor of medicine Dr. William H. Fissell IV, is making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient's own heart. [More]
Kumamoto University researchers identify protein that limits severity of Alport syndrome

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Researchers from Kumamoto University, Japan have identified a protein that limits the severity of Alport syndrome, a type of genetic kidney disease. The finding can provide clues that point toward new therapeutic approaches for Alport syndrome. [More]
Johns Hopkins becomes first center in the U.S. to perform HIV-positive to HIV-positive organ transplants

Johns Hopkins becomes first center in the U.S. to perform HIV-positive to HIV-positive organ transplants

Johns Hopkins recently received approval from the United Network for Organ Sharing to be the first hospital in the U.S. to perform HIV-positive to HIV-positive organ transplants. The institution will be the first in the nation to do an HIV-positive to HIV-positive kidney transplant and the first in the world to execute an HIV-positive to HIV-positive liver transplant. [More]

Study: Only one-third of patients receive living donor kidney transplant pre-emptively

A kidney transplant is a life-changing and life-saving procedure. Yet, a new study conducted by Mayo Clinic and the University of Michigan shows that only one-third of patients who ultimately receive a living donor kidney transplant receive it pre-emptively (i.e., before starting dialysis). Less than two-thirds receive a transplant either pre-emptively or within a year of starting dialysis. [More]
Mild reduction in food intake slows development of autosomal-dominant polycystic kidney disease

Mild reduction in food intake slows development of autosomal-dominant polycystic kidney disease

A small reduction in food intake—less than required to cause weight loss—dramatically slowed the development of a common genetic disorder called autosomal-dominant polycystic kidney disease (ADPKD) in mice, a new study in American Journal of Physiology—Renal Physiology reports. [More]
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