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Caffeine vs. creatine: The impact on cognitive and physical performances

The individual and combined effects of caffeine and creatine nitrate on cognitive and exercise performance.

11 Mar 2024

Study reveals nerve changes linked to pain and urinary frequency in recurrent UTI sufferers

How sensory nerve sprouting and mast cell activity, driven by nerve growth factor (NGF), contribute to persistent bladder pain and dysfunction in recurrent urinary tract infection (rUTI) cases.

7 Mar 2024

Schisanhenol suppresses cytokine storm and acute lung injury in mice

Cytokine storm (CS) is an acute systemic inflammatory response with limited effective interventions up to now.

6 Mar 2024

Interdisciplinary project aims to decode human kinome in brain function and disease

The Chan Zuckerberg Initiative (CZI) announced four multi-year Exploratory Cell Networks grants for researchers exploring the frontiers of genomics, cell biology, and synthetic biology by developing new measurement technologies.

29 Feb 2024

UB research may offer a more streamlined approach to developing cancer drugs

Drug discovery can be a frustrating process of trial and error.

28 Feb 2024

How can food influence the severity of menopausal hot flashes?

Mechanisms and nutrients related to menopause hot flashes.

28 Feb 2024

Resistant starch diet proves a game changer for weight loss and diabetes control

Supplementation with resistant starch leads to weight loss and improved insulin sensitivity by altering the gut microbiome and increasing secondary bile acids, according to a recent study in Nature Metabolism.

27 Feb 2024

Ginseng enhances muscle recovery and reduces fatigue in athletes

Ginseng is one of the most popular food supplements in the world. It is made out of various plants and herbs and is thought to provide many benefits, with numerous studies pointing at possible anti-inflammatory and antioxidant benefits as well as anti-cancer effects.

22 Feb 2024

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling pathway.

19 Feb 2024

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Researchers evaluated rational combination treatment regimens for advanced/metastatic non-small-cell lung cancer (NSCLC).

15 Feb 2024

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field.

14 Feb 2024

Advanced melanoma survival rates improve significantly from 2013 to 2019, Dutch study finds

The change in overall survival (OS) among advanced melanoma patients diagnosed between 2013 and 2021.

14 Feb 2024

Combination therapy offers breakthrough in NSCLC treatment

A specific combination of targeted therapy and immunotherapy may better help patients with non-small cell lung cancer (NSCLC) overcome inherent immune resistance and reinvigorate anti-tumor activity, according to a new study led by a researcher from The University of Texas MD Anderson Cancer Center.

13 Feb 2024

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Combination treatments reduce blood pressure in patients taking ibrutinib

Combination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutinib, according to a new study published in Blood Advances.

5 Feb 2024

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumours Unit of the Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) have found a new therapeutic strategy for patients with a specific subtype of metastatic prostate cancer resistant to standard chemotherapy treatment with docetaxel.

5 Feb 2024

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

One of the major challenges in cancer research and clinical care is understanding the molecular basis for therapeutic resistance as a major cause of long term treatment failures.