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Discovery of protein interaction could lead to new schizophrenia treatments

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.

26 Oct 2023

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

How does nutrition influence osteoarthritis prevention and management?

The influence of nutrition on osteoarthritis (OA).

16 Oct 2023

Genetically edited chickens show resistance to avian influenza in landmark study

Researchers use CRISPR technology to create chickens resistant to avian influenza, targeting specific genes to inhibit viral replication. The study reveals both the promise and complexities of using genetic editing as a disease control strategy, also shedding light on influenza's adaptability.

11 Oct 2023

Recent Advancements in Cell Based Therapy

In this interview, NewsMedical talks to James Brady about cell-based therapy and how the field of genetic engineering transformed.

From MaxCyte, Inc. 11 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

Study demonstrates novel role of Axin1 in mediating intestinal homeostasis and microbiota

A groundbreaking study conducted by Jun Sun's research team at the University of Illinois Chicago has revealed a new and critical role of Axin1 in regulating intestinal epithelial development and microbial homeostasis.

22 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate.

18 Sep 2023

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

After 61 days of observation, NYU Langone Health doctors this month completed the longest-documented case of a genetically engineered pig kidney functioning in a human body.

14 Sep 2023

How COVID-19 targets the pancreas revealed

The study uncovers the role of the PLAC8 protein in making the human pancreas vulnerable to SARS-CoV-2 infection, leading to pancreatic injury and complications in severe COVID-19 cases. The findings open up new avenues for understanding how the virus affects multiple organ systems and offer a potential target for future treatments.

12 Sep 2023

Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscle

Researchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle.

11 Sep 2023

Researchers use machine learning to predict drug approval chances before clinical trials

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. This is vital not only for advancing medicine but also for the overall health and well-being of humanity.

8 Sep 2023

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

The research paper delves into the role of brown adipose tissue and its protein, UCP1, in diet-induced thermogenesis, questioning whether it could be a key to fighting obesity. Despite some evidence suggesting that brown fat activity could influence weight, the study calls for more research to determine the causality between reduced brown adipose tissue activity and obesity.

7 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Review finds correlation between milk oligosaccharides and infant brain development

In a recent article published in Nutrients, researchers investigated the current evidence of the impact of milk oligosaccharides (MOS) on early life neurocognitive and brain development.

30 Aug 2023

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

A study finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis.

22 Aug 2023