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Proteasomes: Expanding roles beyond cellular waste management

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts.

13 Apr 2024

NJHF awards $135K to Kessler Foundation scientists for pilot research projects

This year, New Jersey Health Foundation (NJHF) granted $135,000 in awards to three Kessler Foundation scientists to support pilot research projects that exhibit promising potential.

13 Apr 2024

Study shows exercise can reverse age-related lipid accumulation

Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise.

13 Apr 2024

Study finds dysfunction of key brain systems in people with psychosis

Inside the brains of people with psychosis, two key systems are malfunctioning: a "filter" that directs attention toward important external events and internal thoughts, and a "predictor" composed of pathways that anticipate rewards.

13 Apr 2024

Study reveals metabolic markers linked to long COVID-19 severity

Long COVID-19, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a global health phenomenon characterized by persistent symptoms following the acute phase of COVID-19.

13 Apr 2024

New microfluidic device improves the separation of tumor cells and clusters from malignant effusions

Researchers have unveiled a microfluidic device that significantly improves the separation of tumor cells and clusters from malignant effusions.

13 Apr 2024

AI model can accurately screen for post-traumatic stress disorder after childbirth

A generative artificial intelligence (AI) model that can analyze the narrative accounts of women who have undergone recent childbirth has shown the ability to accurately screen for post-traumatic stress disorder (CB-PTSD), a study by Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system has found.

12 Apr 2024

Hospital sinks fuel antibiotic-resistant bacteria spread

A new study published today in the American Journal of Infection Control reports the infection prevention steps taken to control a months-long multispecies outbreak of carbapenemase-producing Enterobacterales that occurred in a pediatric ward at the Toho University Omori Medical Center in Tokyo in 2017.

12 Apr 2024

Meta-analysis uncovers stress-responsive genes in Arabidopsis

Plants can be temperamental. Even weeds along the side of highways or pushing their way up in the cracks of concrete sidewalks can get stressed out by dehydration, cold, excess salt and more.

12 Apr 2024

Study reveals how DNA gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain various specialized structures - such as the nucleus, mitochondria or peroxisomes - known as "organelles''.

12 Apr 2024

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Sex differences are widespread across human development, physiological processes, and diseases, making it important to characterize the impact of sex differences in these areas.

12 Apr 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

New generative AI tool models the infant microbiome

The gut microbiome has a profound impact on the health and development of infants. Research shows that dysbiosis-;or imbalances in the microbial community-;is associated with gastrointestinal diseases and neurodevelopmental deficits.

10 Apr 2024

Study unlocks how cortisone activates the body’s natural “brakes” on inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

10 Apr 2024

Three-step prostate cancer screening method demonstrates reduced overdiagnosis

A large randomized trial conducted at Tampere University and the University of Helsinki shows that a new three-step prostate cancer screening method can find a considerable number of aggressive cancers.

10 Apr 2024

AI will help heart transplant surgeons to better assess the factors impacting patient outcomes

Artificial intelligence will significantly impact the heart transplantation process by helping physicians better assess the complex factors impacting patient outcomes, according to researchers at today's Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) in Prague.

10 Apr 2024

New technique connects lab-grown "neural organoids" to resemble brain circuits

The idea of growing a functioning human brain-like tissues in a dish has always sounded pretty far-fetched, even to researchers in the field.

10 Apr 2024

Researchers identify the most harmful modifiable risk factors for dementia

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

10 Apr 2024