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Amylin Pharmaceuticals to present new data from its obesity program at Obesity 2009

20. October 2009 00:22
Amylin Pharmaceuticals, Inc. today announced that new data from its obesity program will be presented at Obesity 2009, the 27th Annual Scientific Meeting of The Obesity Society, to be held in Washington, D.C. October 24-28. Phase 2 data from the pramlintide/metreleptin combination treatment clinical program will be the subject of a late-breaking oral presentation. [More]

Leptin can determine osteoarthritis in obese patients

29. September 2009 03:15
The link between obesity and osteoarthritis may be more than just the wear and tear on the skeleton caused by added weight. [More]

Obesity due to leptin deficiency plays major role in knee osteoarthritis

29. September 2009 01:23
In 2005 the World Health Organization (WHO) estimated that globally 400 million adults were obese, defined by a body mass index (BMI) of 30 kg/m2 or greater. WHO projects that by 2015 there will be more than 700 million obese adults worldwide. Obesity is considered to be one of the greatest risk factors for osteoarthritis, a progressive musculoskeletal disorder that is characterized by loss of joint cartilage. [More]

Researchers study functional similarity between zebrafish and humans to fight infections

24. September 2009 07:50
Since the human response to infection is highly complex, research to understand how people fight infection is facilitated by studying how similar processes occur in simpler organisms. Zebrafish are becoming an important model for human disease, since they are easily handled, maintained and manipulated and many fundamental processes between zebrafish and humans are conserved. [More]

Posted in: Medical Science News

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Hormone leptin can regulate bone mass and suppress appetite

24. September 2009 02:16
Contrary to the prevailing view, the hormone leptin, which is critical for normal food intake and metabolism, appears to regulate bone mass and suppress appetite by acting mainly through serotonin pathways in the brain, according to a recent study published in Cell by Yale School of Medicine researchers and colleagues at Columbia University. This new finding contradicts the view that leptin acts primarily in the hypothalamus. [More]

Posted in: Medical Science News

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New therapies boost obesity drug market

16. September 2009 06:27
Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the uptake of novel therapies will drive the obesity drug market to increase more than six-fold, from $512 million in 2008 to more than $3.2 billion in 2018 in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan. [More]

Posted in: Medical Condition News

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High-fat foods can induce binge eating

14. September 2009 01:11
Findings from a new UT Southwestern Medical Center study suggest that fat from certain foods we eat makes its way to the brain. Once there, the fat molecules cause the brain to send messages to the body's cells, warning them to ignore the appetite-suppressing signals from leptin and insulin, hormones involved in weight regulation. [More]

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Reportlinker's report on anti-obesity drugs

11. September 2009 00:57
Reportlinker.com announces that a new market research report is available in its catalogue. [More]

Acceleron's Phase 1 trial of ACE-031 reveals its potential in treating neuromuscular diseases

10. September 2009 10:05
Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, and muscle, today announced preliminary results from the ACE-031 Phase 1 single dose clinical trial demonstrating that ACE-031 increased lean body mass and muscle volume. The results from this randomized, placebo-controlled study were presented at the 14th International Congress of the World Muscle Society in Geneva, Switzerland. [More]

Posted in: Drug Trial News

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Scientists shed light on the relationship between hypertension and obesity

2. September 2009 01:58
Some of the first information about how fat causes hypertension have been identified by researchers who say the findings should one day help identify which obese people - and maybe some thin ones too - are at risk for hypertension and which drugs would work best for them. [More]

Fruit flies' fat-store levels can be measured and controlled by brain neuron manipulation

19. August 2009 03:03
A team of scientists from the California Institute of Technology (Caltech) have pinpointed two groups of neurons in fruit fly brains that have the ability to sense and manipulate the fly's fat stores in much the same way as do neurons in the mammalian brain. [More]

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Obesity leads to worse prostate cancer in both black and whites equally

13. August 2009 23:51
A new look at a large database of prostate cancer patients shows that obesity plays no favorites when it comes to increasing the risk of recurrence after surgery: Being way overweight is equally bad for blacks and whites, say researchers at Duke University Medical Center. [More]

Tissue scarring key to link between obesity and diabetes

13. August 2009 23:35
The team, in collaboration with University Hospital Aintree, the University of Warwick and researchers in Sweden, found that people classified as obese and those with pre-diabetes have raised levels of a protein called SPARC, that can cause tissue scarring. [More]

Posted in: Medical Research News

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Leptin influences baseline dopamine levels and motivation to eat

5. August 2009 21:26
As we all know from experience, people eat not only because they are hungry, but also because the food just simply tastes too good to pass up. Now, a new study in the August 6th Cell Metabolism, a Cell Press publication, helps to explain how leptin, a hormone produced by fat tissue, influences that motivation to eat. [More]

Posted in: Medical Research News

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Jeffrey Friedman receives Shaw Prize for discovery of leptin

16. June 2009 16:55
Jeffrey M. Friedman, Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics at Rockefeller University, has received the 2009 Shaw Prize in Life Science and Medicine. The prize was announced today by the Hong Kong-based Shaw Prize Foundation. [More]

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