Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Gut bacteria play a pivotal role in obesity's impact on body fat metabolism

Review explores the complex interplay between gut microbiota dysregulation in obesity and its impacts on white and brown adipose tissue metabolism, focusing on direct and indirect effects on mitochondria, highlighting potential avenues for obesity treatment through microbiota-focused strategies.

11 Apr 2024

The complex relationship between obesity and male reproductive function

Authors have analyzed current evidence on the impact of obesity on the male reproduction system.

9 Apr 2024

Study identifies genetic variants with profound impact on obesity risk

A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.

4 Apr 2024

Age-related changes in the shape of brain neurons lead to middle-age obesity

Nagoya University researchers and their colleagues in Japan have found that middle-age obesity is caused by age-related changes in the shape of neurons in the hypothalamus, a region of the brain that controls metabolism and appetite.

13 Mar 2024

Obesity related to depression risk among older adults

Researchers discuss the association between depression and obesity.

12 Mar 2024

Gut bacteria diversity linked to body weight, athletes show healthier profiles

Systematic review reveals gut microbiome variations correlate with body composition changes across lifespan, highlighting differences between obese individuals and athletes.

29 Feb 2024

How can food influence the severity of menopausal hot flashes?

Mechanisms and nutrients related to menopause hot flashes.

28 Feb 2024

Genes dictate taste: Study finds genetic links to food preferences

Study reveals the significant impact of genetic variations on adult dietary preferences, highlighting the complex interplay between genetics and food choices.

13 Feb 2024

Fermented foods linked to mental health benefits through gut-brain connection

Researchers explore the mental health benefits of fermented foods on the microbiota-gut-brain axis, highlighting the need for further studies to understand their therapeutic potential.

29 Jan 2024

Key protein EPAC1 found to regulate brown fat growth, offering obesity treatment potential

Study reveals that EPAC1 protein plays a crucial role in regulating the growth of brown and beige adipose tissue, offering potential avenues for treating obesity and improving cardiometabolic health.

11 Jan 2024

Does intermittent fasting improve your sports performance?

The effects of intermittent fasting on sports performance.

8 Jan 2024

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Study reveals that cinnamon extract significantly inhibits adipocyte differentiation and lipid accumulation, offering potential benefits against obesity by reducing fat production and enhancing lipolysis in both cell models and mice.

18 Dec 2023

Fasting-mimicking diet shows unique benefits in cardiovascular health, study finds

Study compares the fasting-mimicking diet and the Mediterranean diet in reducing cardiovascular disease risk among obese adults with hypertension, revealing unique benefits of each diet.

17 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Plant-based diets and genetic risk for obesity

The potential link between plant-based dietary patterns (plant-based dietary indices, PDI) and genetic risk of obesity.

8 Dec 2023

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Influence of healthy lifestyle habits on chronic disorders

The health benefits of regular exercise, a healthy diet, and adequate sleep.

2 Nov 2023

UCD professor wins ERC Synergy grant to unlock the secrets to healthy aging

Do bats hold the secret to health and longevity? A team led by Professor Emma Teeling, Full Professor of Zoology at University College Dublin (UCD), has won a prestigious European Research Council (ERC) Synergy grant of almost €12 million, to explore this fascinating question.

26 Oct 2023