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Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024

Dietary protein overload linked to increased atherosclerosis risk

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.

19 Feb 2024

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling pathway.

19 Feb 2024

Healthy lifestyles linked to specific metabolic markers, large study finds

Researchers identify metabolomic markers linked to healthy lifestyles in a large study, showing a connection between lipid metabolism and reduced mortality risks.

18 Feb 2024

Study explores the mediatory role of gut microbiota in metabolic syndrome and sleep disorders

Researchers described gut microbiota and metabolic alterations common to metabolic syndrome (MetS) and sleep disorders.

31 Jan 2024

Neonates exposed to SARS-CoV-2 in utero at higher risk of respiratory distress, study finds

Researchers found that neonates born to mothers with SARS-CoV-2 infection face an increased risk of respiratory distress, potentially due to an inflammatory response triggered by prenatal exposure.

29 Jan 2024

St. Jude researchers reveal structure of Parkinson's-linked proteins

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

21 Dec 2023

New approach enhances CAR T-cell therapy for solid tumors

Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia.

30 Nov 2023

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Researchers used a Mendelian randomization approach to conduct a genetic association analysis of the levels of over 3,000 proteins to identify biomarkers for early breast cancer detection.

28 Nov 2023

Genome study unveils genetic ties between cannabis use disorder and lung cancer risk

A genome-wide association study in Nature Genetics reveals insights into the genetics of cannabis use disorder, highlighting its strong association with psychopathology and a causal link to lung cancer, and suggesting distinct genetic pathways from mere cannabis use.

23 Nov 2023

Research reveals both protective and harmful gut microbiota associated with sleep apnea risk

The causal relationship between gut microbiota, associated metabolites, and obstructive sleep apnea (OSA).

30 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Spanish researchers use cisgenic engineering to create nutrient-packed tomatoes with higher levels of flavonoids and branched-chain amino acids, providing potential benefits for those on plant-based diets. The study shows promise for enhancing nutritional content in other crops, addressing malnutrition and health deficiencies.

27 Sep 2023

CD1 lipidomes exhibit size-based antigen display mechanisms

Study uncovers the complexities of how CD1 molecules present a vast array of lipids to T-cells, revealing a unique, size-based antigen-display system. The findings could provide crucial insights into the intricacies of immune response and antigen presentation.

21 Sep 2023

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

The interaction of caffeine with Leucine rich repeat kinase 2 (LRRK2) genetic risk variants in Asians.

8 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023