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Liver cancer is more common in older people. Over half of people newly diagnosed with liver cancer are age 65 and over. Liver cancer is more common in men than in women. Liver cancer rates are highest among Asians and Pacific Islanders, most likely because of higher prevalence of viral Hepatitis infection. Liver cancer rates are lower among whites than Blacks or Asians and Pacific Islanders. At this time, we do not know exactly what causes cancer of the liver. There are several different types of liver cancer. The most common type is associated with long-term excessive alcoholic beverage use, scarring of the liver (cirrhosis), and Hepatitis B virus or Hepatitis C virus infection. Long-term use of anabolic steroids can also increase the risk of getting liver cancer. Smoking is also believed to increase the risk of getting liver cancer.
MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment. [More]
Study provides insights into CPEB4 gene and fatty liver disease

Study provides insights into CPEB4 gene and fatty liver disease

This condition generally leads to chronic inflammation (non-alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study on the basic biology of the liver paves the way to examine therapeutic strategies to fight and prevent fatty liver disease. [More]
New report reveals 25% drop in overall cancer death rate in the U.S.

New report reveals 25% drop in overall cancer death rate in the U.S.

A steady decline over more than two decades has resulted in a 25% drop in the overall cancer death rate in the United States. The drop equates to 2.1 million fewer cancer deaths between 1991 and 2014. [More]
Natural antioxidant can protect offspring of obese mice from NAFLD, study shows

Natural antioxidant can protect offspring of obese mice from NAFLD, study shows

A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease in the offspring of obese mice, according to researchers at the University of Colorado Anschutz Medical Campus. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Combination of diabetes and hypertension drugs can effectively treat cancer

Combination of diabetes and hypertension drugs can effectively treat cancer

A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells. [More]
Scientists unravel novel role of signalling protein in common type of liver cancer

Scientists unravel novel role of signalling protein in common type of liver cancer

The most common type of liver cancer, called Hepatocellular carcinoma, is one of the most prevalent tumours worldwide. [More]
Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Researchers of the TGF-beta and Cancer group of Bellvitge Biomedical Research Institute, in collaboration with King's College London, have unveiled the role of NADPH oxidase NOX4 as an inhibitor of the epithelial-amoeboid transition, a process that contributes to the migration and invasion of tumor cells. [More]
Researchers discover new pathway that opens door to treat non-alcoholic fatty liver disease

Researchers discover new pathway that opens door to treat non-alcoholic fatty liver disease

Researchers from the University of South Carolina, Duke University, University of Alabama at Birmingham, and Metabolon Inc. Research Triangle Park have discovered a new pathway in the liver that opens the door to treat non-alcoholic fatty liver disease, a condition that affects up to 25 percent of the population and may lead to cirrhosis and eventually liver cancer or failure, and likely other liver diseases. [More]
NASPGHAN clinical practice guidelines recommend screening test for NAFLD in obese children

NASPGHAN clinical practice guidelines recommend screening test for NAFLD in obese children

A screening test for non-alcoholic fatty liver disease (NAFLD)--a serious condition that may have lifelong health consequences--is recommended for all obese children aged nine to eleven years, according to clinical practice guidelines developed by the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and published in the Journal of Pediatric Gastroenterology and Nutrition. [More]
New green nanotechnology approach targets, destroys precancerous tumor cells in livers of mice

New green nanotechnology approach targets, destroys precancerous tumor cells in livers of mice

According to the American Cancer Society, more than 700,000 new cases of liver cancer are diagnosed worldwide each year. [More]
Research provides insight into molecular mechanisms involved in immune response to HBV

Research provides insight into molecular mechanisms involved in immune response to HBV

The innate immune system in mammals defends against infection from viruses and other microbial infections. [More]
Low-calorie diet and exercise could improve kidney function in patients with NASH

Low-calorie diet and exercise could improve kidney function in patients with NASH

Non-alcoholic steatohepatitis (NASH) is a potentially serious liver condition characterized by excess fat in the liver associated with inflammation and scarring. [More]
New public-private partnership launches major health effort to reduce cancer in San Francisco

New public-private partnership launches major health effort to reduce cancer in San Francisco

Cancer is the leading cause of death in San Francisco and costs patients, families and taxpayers hundreds of millions of dollars each year. [More]
Study finds way to increase liver cancer screening rates among at-risk cirrhosis patients

Study finds way to increase liver cancer screening rates among at-risk cirrhosis patients

Proactive outreach to cirrhosis patients in a safety net health system successfully doubled their screening rates for liver cancer, UT Southwestern Medical Center researchers found. [More]
Alcohol to cause 135,000 cancer deaths over next 20 years, news report reveals

Alcohol to cause 135,000 cancer deaths over next 20 years, news report reveals

Alcohol will cause around 135,000 cancer deaths over the next 20 years and will cost the NHS an estimated £2 billion in treatments, according to estimates from a new report by Sheffield University, commissioned by Cancer Research UK. [More]
Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

The virus that causes hepatitis C protects itself by blocking signals that call up immune defenses in liver cells, according to University of Washington researchers and colleagues reporting Nov. 14 in Nature Medicine. [More]
HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

A new study presented this week at The Liver Meeting — held by the American Association for the Study of Liver Diseases — found patients with hepatitis C who take direct-acting antiviral medication are at no higher risk for developing liver cancer than those who do not take the medication. [More]
Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

The links between Type 2 diabetes and cancer are complex: people suffering from diabetes mellitus essentially have a higher risk of developing cancer but, on top of that, some diabetes drugs are also suspected of increasing the risk in some cases. [More]
New treatment can halt growth of liver cancer cells, research shows

New treatment can halt growth of liver cancer cells, research shows

Scientists have shown that a mutation in a gene called Arid1b can cause liver cancer. The gene normally protects against cancer by limiting cell growth, but when mutated it allows cells to grow uncontrollably. [More]
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