Liver Transplant News and Research

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When a patient presents with end stage liver disease or liver failure he or she may be considered for a liver transplantation. The first step in this is often a rigorous assessment and being placed on a waiting list.

NYU Langone achieves highest-quality kidney and lung transplant results in the U.S.

The NYU Langone Transplant Institute had the highest-quality kidney and lung transplant outcomes in the nation in 2023, according to federal quality data, while its heart and liver transplant programs reached new heights last year.

15 Apr 2024

Bio-Rad announces collaboration agreement with oncocyte to commercialize transplant monitoring with droplet digital PCR

Collaboration Aims to Provide Researchers Cutting-Edge Tools to Enable Transformational Monitoring of Key Biomarkers in Solid Tissue Transplants.

From Bio-Rad Laboratories 15 Apr 2024

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Adding a personalized anti-tumor vaccine to standard immunotherapy is safe and about twice as likely to shrink cancer as standard immunotherapy alone for patients with hepatocellular carcinoma, the most common type of liver cancer, according to a clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and its Convergence Institute.

8 Apr 2024

Gene defect associated with argininosuccinic aciduria corrected using CRISPR-Cas9 technique

Argininosuccinate lyase deficiency (ASLD), also known as argininosuccinic aciduria, is a disease that has been enriched in the Finnish genetic heritage.

4 Apr 2024

Food insecurity fuels fatty liver disease in Latinx kids

For Latinx kids, unreliable access to food at age 4 raises the odds of having fatty liver disease later in childhood by nearly four times, a new UC San Francisco-led study found.

9 Mar 2024

SickKids study offers new path for pediatric rare disease clinical trials

Using a novel methodology, researchers at The Hospital for Sick Children (SickKids) are the first in pediatric research to use data from an international real-world cohort to overcome the barriers associated with conducting randomized clinical trials in children with rare diseases.

29 Feb 2024

Stigmatizing language on websites delays care for liver disease patients

The vast majority of liver transplant centers in the United States use language on their websites that can be considered stigmatizing through their use of words like "alcoholism," "alcoholic" and "alcohol abuse,' potentially hindering care and the willingness of patients to seek treatment, a study by Massachusetts General Hospital (MGH) has found.

8 Feb 2024

£30M clinical study will enhance the understanding of NASH cirrhosis

The most extensive clinical study into liver cirrhosis ever conducted worldwide has been announced by Newcastle University, University of Edinburgh and leading research-driven global biopharmaceutical company, Boehringer Ingelheim.

8 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

AI advances could revolutionize hepatocellular carcinoma diagnosis

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. It is a major global health concern with rising rates, particularly in North Africa and East Asia.

28 Dec 2023

Poop-based test predicts postoperative infections in liver transplant patients

In a new study, researchers at the University of Chicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop.

15 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

Live vaccinations found to be safe for pediatric organ transplant recipients

Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions, according to a new study published Oct. 12, 2023, in JAMA Network Open.

16 Oct 2023

Pitt scientists develop new approach to reduce side effects of organ transplants

Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe – and may lead to recipients being successfully weaned off immunosuppressant medications without rejecting the transplanted organ.

11 Oct 2023

Living donor liver transplantation improves waitlist outcomes in high-risk cirrhosis patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients."

26 Sep 2023

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

After 61 days of observation, NYU Langone Health doctors this month completed the longest-documented case of a genetically engineered pig kidney functioning in a human body.

14 Sep 2023

NYU Langone offers the highest-quality kidney and lung transplant programs in the nation, new U.S. data reveals

The NYU Langone Transplant Institute offers the highest-quality kidney and lung transplant programs in the nation, according to new federal quality data, while its heart and liver transplant programs hold the highest organ survival rates in New York.

8 Sep 2023

New matching system enables world's first four-way liver exchange

In a breakthrough in liver transplantation that may lead to the ability to connect more living donors and patients, a new matching system designed by a team led by Boston College economists enabled the world's first four-way liver exchange and a cascade of additional matches, researchers reported recently in the American Journal of Transplantation.

22 Aug 2023

Proteins CEACAM1 and TIM-3 may help protect liver transplants

A new study identifies how certain proteins in the immune system interact leading to organ rejection. The study, which involved experiments on mice and human patients, uncovered an important communication pathway between two molecules called CEACAM1 (CC1) and TIM-3, finding that the pathway plays a crucial role in controlling the body's immune response during liver transplantation.

19 Jul 2023

Normothermic machine preservation shows promise in liver transplantation

A groundbreaking clinical trial comparing conventional low temperature storage of transplant donor livers with storage at physiological body temperature has revealed promising results for the evolution of liver transplantation.

17 Jul 2023