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Researchers develop new method that can target drug delivery to the lung

Researchers develop new method that can target drug delivery to the lung

Researchers from Columbia Engineering and Columbia University Medical Center have developed a new method that can target delivery of very small volumes of drugs into the lung. [More]
SLU scientist receives grant to solve blood-clotting mysteries

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs. [More]

Individually tailored treatment may help reduce mortality risk in patients undergoing routine surgeries

Cholecystectomy and treatment for inguinal, femoral, umbilical, or abdominal hernia are common surgeries and are considered routine in Germany. In an original article in the current edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 112: 535-43), Ulrike Nimptsch and Thomas Mansky show that fewer than 0.5% of patients die as a result of such surgeries. [More]
ieCrowd announces achievement of major milestone in commercial development of Smart Oxygen device

ieCrowd announces achievement of major milestone in commercial development of Smart Oxygen device

ieCrowd today announced the achievement of an important milestone in the commercial development of the company's supplemental oxygen delivery device, Smart Oxygen. The Smart Oxygen device, being developed by ieCrowd's subsidiary Smart Oxygen Solutions, automatically adjusts to a patient's changing demand for oxygen based on level of activity. [More]
SLU study finds that length of stay in ED makes no real difference in mortality of trauma patient

SLU study finds that length of stay in ED makes no real difference in mortality of trauma patient

The amount of time a trauma patient stays in the emergency department (ED) makes no real difference in the patient's mortality, researchers at Saint Louis University found in a recent study. [More]
PFF, Veracyte partner on U.S. survey exploring patients' diagnostic experiences with interstitial lung diseases

PFF, Veracyte partner on U.S. survey exploring patients' diagnostic experiences with interstitial lung diseases

The Pulmonary Fibrosis Foundation and Veracyte, Inc. announced that the organizations are partnering on a U.S. patient survey to advance understanding of patients' diagnostic experiences with interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF). [More]
FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

Boehringer Ingelheim today announced that both the U.S. Food and Drug Administration and the European Medicines Agency have accepted filing applications for afatinib for the treatment of patients with advanced squamous cell carcinoma (SCC) of the lung progressing after treatment with first-line chemotherapy. [More]
Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans. [More]
SLUCare cardiac surgeon aims to connect underserved population in St. Louis region with health care services

SLUCare cardiac surgeon aims to connect underserved population in St. Louis region with health care services

A new project spearheaded by a Saint Louis University cardiac surgeon is aiming to connect an underserved population with health care services in the St. Louis region. [More]
U-M microbiome research may lead to new ways to prevent, fight lung infections in patients

U-M microbiome research may lead to new ways to prevent, fight lung infections in patients

With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers at the University of Michigan Medical School have started to answer these questions by studying the microbiome of the lungs - the community of microscopic organisms that are in constant contact with our respiratory system. [More]
New OTEMTO phase three results show potential improvement to quality of life for COPD patients

New OTEMTO phase three results show potential improvement to quality of life for COPD patients

Boehringer Ingelheim announced the publication of new data from the Phase IIIb OTEMTO® 1&2 trials (NCT01964352/NCT02006732), which show Spiolto® Respimat® (tiotropium/olodaterol) provides consistent, clinically meaningful improvements in quality of life versus placebo in patients with COPD [More]
Legal-Bay reports that death toll from Legionnaires' disease outbreak in South Bronx rises to 7

Legal-Bay reports that death toll from Legionnaires' disease outbreak in South Bronx rises to 7

Legal-Bay LLC, The Lawsuit Settlement Funding Company, reports that in the tragic Legionnaires' disease outbreak sweeping the South Bronx, 81 cases have been reported as of now, with a total of 7 people dead as a result. According to NYC health officials, 81 cases have been reported in total, with 64 of those requiring hospitalization, and the death roll has recently risen to 7. [More]
Hospital physicians rarely identify or address overweight/obesity in children

Hospital physicians rarely identify or address overweight/obesity in children

Physicians and physician trainees fail to identify or address overweight/obesity in over 90 percent of hospitalized children, according to new research from a Saint Louis University pediatric hospitalist. [More]
Pharmaxis, Synairgen partner to develop LOXL2 inhibitor to treat idiopathic pulmonary fibrosis

Pharmaxis, Synairgen partner to develop LOXL2 inhibitor to treat idiopathic pulmonary fibrosis

Australian pharmaceutical company Pharmaxis Ltd and UK biotechnology company Synairgen plc today announced they have entered into a research collaboration to develop a selective inhibitor to the lysyl oxidase type 2 enzyme (LOXL2) to treat the fatal lung disease idiopathic pulmonary fibrosis (IPF). [More]
Study shows link between liver-produced molecules, pneumonia susceptibility during sepsis

Study shows link between liver-produced molecules, pneumonia susceptibility during sepsis

New evidence highlights the importance of the liver in immunity against bacterial pneumonia. The study is the first of its kind to directly show such a link between liver-produced molecules and pneumonia susceptibility during sepsis. [More]
Researchers develop dynamic functional mouse model for lung injury repair

Researchers develop dynamic functional mouse model for lung injury repair

Researchers at Children's Hospital Los Angeles and The Saban Research Institute of CHLA have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease and provide a system by which new therapies can be identified and tested. [More]
New research reveals how DNA influences severity of any genetic disease

New research reveals how DNA influences severity of any genetic disease

That two people with the same disease-causing mutation do not get sick to the same extent has been puzzling scientists for decades. Now Professor Andy Fraser and his team have uncovered a key part of what makes every patient different. [More]
Adverse life events in childhood can increase woman's risk of preterm birth

Adverse life events in childhood can increase woman's risk of preterm birth

Like most health professionals, David Olson has known for some time of the dangers posed by excessive stress. His latest research, though, is giving surprising new insight into how chronic stress in childhood can have an impact years after it occurred in women giving birth. [More]
SLU researcher awarded NIH's Cutting-Edge Basic Research Award to solve pain-killer problem

SLU researcher awarded NIH's Cutting-Edge Basic Research Award to solve pain-killer problem

SLU pain researcher Daniela Salvemini has been awarded the NIH's Cutting-Edge Basic Research Award (CEBRA) to solve an alarming problem: pain killers that are capable of quelling terrible pain also carry debilitating side effects and significant risk of addiction. [More]
Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Researchers recommend performing echocardiography at rest and during exercise to screen for pulmonary arterial hypertension in patients with systemic sclerosis. [More]
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