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Lung cancer is the world's most common cancer and kills more people than any other cancer. In 2008, approximately 1.52 million new cases of lung cancer were diagnosed worldwide, with 1.31 million people dying from the disease.(14) In the United States, an estimated 161,840 deaths, accounting for 29 percent of all cancer deaths, occurred in 2008, according to the American Cancer Society (ACS).
Obesity genes promote all-round increases in postnatal growth

Obesity genes promote all-round increases in postnatal growth

Genetic variants that increase susceptibility to obesity are associated with increased gains in lean mass, as well as fat mass, during early childhood, meta-analysis findings indicate. [More]
Rare neuroendocrine tumours may be misdiagnosed as Cushing’s disease

Rare neuroendocrine tumours may be misdiagnosed as Cushing’s disease

Ectopic tumours secreting corticotropin-releasing hormone and adrenocorticotropic hormone are very rare in children and can result in a misdiagnosis of Cushing’s disease, say researchers. [More]
Growth hormone worthwhile treatment in hypochondroplasia

Growth hormone worthwhile treatment in hypochondroplasia

Researchers report that recombinant human growth hormone can improve growth in children with hypochondroplasia. [More]
Promising results for low-dose insulin in paediatric diabetic ketoacidosis

Promising results for low-dose insulin in paediatric diabetic ketoacidosis

Results of a randomised trial suggest that low-dose insulin may be at least as good as standard-dose insulin for the treatment of children with diabetic ketoacidosis. [More]
Hypocalcaemic seizure surveillance highlights UK public health policy failings

Hypocalcaemic seizure surveillance highlights UK public health policy failings

The occurrence of 91 confirmed or probable hypocalcaemic seizures in children with vitamin D deficiency over a 2-year period in the UK highlights a failure to promote appropriate supplementation. [More]
EGFR–TKIs linked to reduced chemotherapy sensitivity in NSCLC

EGFR–TKIs linked to reduced chemotherapy sensitivity in NSCLC

Epidermal growth factor receptor–tyrosine kinase inhibitors appear to significantly reduce the efficacy of subsequent chemotherapy in patients with EGFR-mutated non-small-cell lung cancer, Chinese researchers report. [More]
Inappropriate lung cancer imaging widespread in USA

Inappropriate lung cancer imaging widespread in USA

A large proportion of patients with lung cancer do not receive guideline-recommended imaging, US study data show. [More]
Endemic lung infection compromises lung cancer diagnosis

Endemic lung infection compromises lung cancer diagnosis

The accuracy of lung cancer diagnosis using 18F-fluorodeoxyglucose–positron emission tomography may be compromised in areas with endemic infectious lung diseases, research suggests. [More]
Adjuvant cisplatin for NSCLC raises non-cancer mortality risk

Adjuvant cisplatin for NSCLC raises non-cancer mortality risk

Re-analysis of data from the International Adjuvant Lung Cancer Trial indicates that cisplatin-based adjuvant chemotherapy increases the long-term risk of non-cancer mortality in patients with non-small-cell lung cancer. [More]
Intrathoracic radiotherapy shows potential in extensive-stage SCLC

Intrathoracic radiotherapy shows potential in extensive-stage SCLC

A phase III randomised controlled trial shows that intrathoracic radiotherapy after chemotherapy significantly reduces the chances of disease progression in patients with extensive-stage small-cell lung cancer. [More]
Golden Jubilee National Hospital holds performance review in public

Golden Jubilee National Hospital holds performance review in public

Today, the Golden Jubilee National Hospital held its Annual Review, demonstrating that they have continued to lead the way in safe, effective and person centred care for the NHS in Scotland. [More]
Covidien unveils new version of superDimension Navigation System software for diagnosis of lung cancer

Covidien unveils new version of superDimension Navigation System software for diagnosis of lung cancer

Further underscoring its ongoing commitment to lung health, Covidien today unveiled a next-generation version of its superDimension™ Navigation System software. The updated software features a more intuitive interface that helps reduce time spent by physicians planning the procedure and enhances the visualization of the airways of the lung. [More]
Concord Medical gets approval to establish Datong Meizhong Jiahe Cancer Center

Concord Medical gets approval to establish Datong Meizhong Jiahe Cancer Center

Concord Medical Services Holdings Limited, an operator of specialty cancer hospitals and the largest network of radiotherapy and diagnostic imaging centers in China, today announced that the Company has received relevant government approvals to establish a free-standing radiotherapy cancer center, Datong Meizhong Jiahe Cancer Center ("Datong Center") in Datong City, Shanxi Province. [More]
Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

A Virginia Tech professor is working on a vaccine that could help smokers conquer their nicotine addiction, making many smoking-related diseases and deaths relics of the 21st century. [More]
MIT researchers develop new way to model effects of cancer-causing genetic mutations

MIT researchers develop new way to model effects of cancer-causing genetic mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process. [More]
Afatinib active against NSCLC nervous system metastases

Afatinib active against NSCLC nervous system metastases

Heavily pretreated patients with epidermal growth factor receptor-mutated non-small-cell lung cancer and central nervous system metastases may benefit from treatment with afatinib, say German researchers. [More]
Six platinum cycles no better than four for advanced NSCLC

Six platinum cycles no better than four for advanced NSCLC

Six cycles of adjuvant platinum-based chemotherapy is no better than three or four cycles for patients with advanced non-small-cell lung cancer, meta-analysis results suggests. [More]
Van Andel Research Institute commits $7.5M to support epigenetic therapy in cancer treatment

Van Andel Research Institute commits $7.5M to support epigenetic therapy in cancer treatment

The work of one of the Stand Up To Cancer (SU2C) inaugural Dream Teams, launched in 2009 to focus on epigenetic therapy in cancer treatment, will continue with the commitment of $7.5 million from Van Andel Research Institute (VARI). [More]
Asterias, CIRM sign NGA to begin AST-OPC1 study for complete cervical spinal cord injury

Asterias, CIRM sign NGA to begin AST-OPC1 study for complete cervical spinal cord injury

Asterias Biotherapeutics, Inc. announced today that the Company has signed a Notice of Grant Award (NGA) with the California Institute of Regenerative Medicine (CIRM), effective October 1, 2014. [More]
Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen Research & Development, LLC today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA (ibrutinib) to the U.S. Food and Drug Administration by its strategic partner Pharmacyclics, Inc. [More]