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Low mammographic breast density linked to worse prognosis in breast cancer patients

Low mammographic breast density linked to worse prognosis in breast cancer patients

Even though dense breast tissue is a risk factor for breast cancer, very low mammographic breast density is associated with a worse prognosis in breast cancer patients. [More]
Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed. [More]
Legions of immune cells play complex role to destroy Legionella bacteria

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria. [More]
Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

When the body is fighting an invading pathogen, white blood cells--including T cells--must respond. Now, Salk Institute researchers have imaged how vital receptors on the surface of T cells bundle together when activated. [More]
PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar today announced the start of a multicenter, prospective, pivotal study to analyze the efficacy of the antitumoral compound of marine origin, plitidepsin in patients with relapsed and refractory angioimmunoblastic T-cell lymphoma. [More]
New ultrasensitive magnetometer probe system for detecting cancer moves towards commercialisation

New ultrasensitive magnetometer probe system for detecting cancer moves towards commercialisation

Researchers at the University of South Australia’s Future Industries Institute have joined forces with New Zealand-based nanoparticle specialist Boutiq Science and major IP investor, Powerhouse Ventures. [More]
Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Identifying the cell of origin is crucial to understanding how a tumor develops and metastasizes and for developing targeted therapies. [More]
Pembrolizumab drug shows significant clinical responses in metastatic head and neck cancer patients

Pembrolizumab drug shows significant clinical responses in metastatic head and neck cancer patients

Treating head and neck cancer patients with recurrent or metastatic disease with the PD-1 inhibitor pembrolizumab resulted in significant clinical responses in a fifth of the patients from a phase II clinical trial, researchers at the Abramson Cancer Center of the University of Pennsylvania and other institutions reported at the 2016 American Society of Clinical Oncology annual meeting. [More]
Zinbryta gets FDA approval for treating adults with relapsing forms of MS

Zinbryta gets FDA approval for treating adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Zinbryta (daclizumab) for the treatment of adults with relapsing forms of multiple sclerosis (MS). Zinbryta is a long-acting injection that is self- administered by the patient monthly. [More]
Study shows birth defects in immune system function may contribute to malnutrition

Study shows birth defects in immune system function may contribute to malnutrition

Malnourished children are most likely to die from common infections, not starvation alone, and immune disorder may be part of the cause, according to a review led by Queen Mary University of London. [More]
ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Initiating antiretroviral therapy (ART) soon after diagnosis of an HIV infection did not prevent the progression of significant arterial inflammation in a small group of previously untreated patients. [More]
Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals. [More]
Robotic VATS could be safe alternative to conventional thoracoscopic procedures for lung cancer treatment

Robotic VATS could be safe alternative to conventional thoracoscopic procedures for lung cancer treatment

A new study shows that robotic video-assisted lung resection to remove a tumor achieves comparable outcomes with no significant differences in complications compared to conventional video-assisted thoracoscopic surgery (VATS), and robotic VATS (RVATS) may allow for preservation of more healthy lung tissue. [More]
Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine. [More]
Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Loyola researchers have identified a tumor gene that may help to predict survival outcomes in patients with cancer of the mouth and tongue. [More]
Real risk of rebound syndrome following fingolimod cessation for MS

Real risk of rebound syndrome following fingolimod cessation for MS

Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs. [More]
Liposuction to manage lymphedema? An interview with Professor John Boyages

Liposuction to manage lymphedema? An interview with Professor John Boyages

Lymphedema is persistent swelling of the arm and/or hand following biopsy or treatment of the axillary lymph nodes for patients with breast cancer. It is due to excess accumulation of protein‐rich fluid in body tissues. [More]
Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis. [More]
LJI study could provide important target for autoimmune disease interventions

LJI study could provide important target for autoimmune disease interventions

Follicular helper T cells (Tfh cells), a rare type of T cells, are indispensable for the maturation of antibody-producing B cells. They promote the proliferation of B cells that produce highly selective antibodies against invading pathogens while weeding out those that generate potentially harmful ones. [More]
UGA researcher works to advance effective treatment for infectious mononucleosis

UGA researcher works to advance effective treatment for infectious mononucleosis

The University of Georgia's Mark Ebell wasn't impressed with research on infectious mononucleosis when he wrote his first published review on it back in the 1990s. He still isn't—a subject he discusses in the April issue of the Journal of the American Medical Association. [More]
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