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Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study. [More]
Scientists develop 3-D organoid to unravel immune response during infection

Scientists develop 3-D organoid to unravel immune response during infection

What if you could design an adaptable, biomaterials-based model of an organ to track its immune response to any number of maladies, including cancer, transplant rejection and the Zika virus? The lab of Ankur Singh, assistant professor in the Sibley School of Mechanical and Aerospace Engineering, has asked - and begun to answer - that very question. [More]
Delayed chemotherapy after surgery may benefit lung cancer patients, new Yale study suggests

Delayed chemotherapy after surgery may benefit lung cancer patients, new Yale study suggests

A new Yale study suggests that patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to the researchers. [More]
HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

Deregulation and inhibition of the immune system contributes to cancer development. Many therapeutic strategies aim to restimulate the immune system to recognize cancer cells and target them for destruction. [More]
Study suggests new options for improving cancer immunotherapy

Study suggests new options for improving cancer immunotherapy

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system. [More]
IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2-negative breast cancer and up to 3 affected lymph nodes. [More]
Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment. [More]
High-fat, low-sugar diet prior to imaging can help reduce uncertainty in diagnosing cardiac sarcoidosis

High-fat, low-sugar diet prior to imaging can help reduce uncertainty in diagnosing cardiac sarcoidosis

Researchers at the University of Illinois at Chicago were able to reduce uncertainty in diagnosing cardiac sarcoidosis by having patients consume a high-fat, low-sugar diet for 72 hours prior to diagnostic imaging. [More]
Study provides new insights into fundamental characteristics of dendritic cells

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD

FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD

A new proof of concept study has shown that an imaging technique more commonly used to assess cancer patients may also be of help in assessing disease and treatment effects in patients with inflammatory diseases. [More]
New study sheds light on how immune system functions during sleep

New study sheds light on how immune system functions during sleep

A new study sheds light on how the immune system replenishes itself during sleep. Researchers found that some subsets of T cells are reduced from the bloodstream during sleep when risk of infection is low. [More]
New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research has shown how the immune system avoids attacking its own tissues with antibodies - whilst still maintaining a strong defence against invaders. [More]
Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

A study led by researchers at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research, Janssen Vaccines & Prevention B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson and Gilead Sciences, Inc., has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV. [More]
Investigational treatment combination improves virologic control in SIV-infected monkeys

Investigational treatment combination improves virologic control in SIV-infected monkeys

Researchers have found that an investigational treatment combination of a therapeutic vaccine and an immune-stimulator improves virologic control and delays viral rebound following the discontinuation of antiretroviral therapy (ART) in non-human primates infected with SIV, the simian form of HIV. [More]
Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events. [More]
Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events. [More]
New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

A blood test that has shown promise in predicting how cancer will progress and what treatments will be most effective for a given patient may not be reliable for either, according to a new Penn Medicine study published this week in Cancer, a peer-reviewed journal of the American Cancer Society. [More]
New approach could overcome large immunosuppressive tumors

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality. [More]
New study examines how tumor genome testing helps improve breast cancer treatment

New study examines how tumor genome testing helps improve breast cancer treatment

A new study examines how one early example of precision medicine--tumor genome testing--is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy. [More]
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