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Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD

FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD

A new proof of concept study has shown that an imaging technique more commonly used to assess cancer patients may also be of help in assessing disease and treatment effects in patients with inflammatory diseases. [More]
New study sheds light on how immune system functions during sleep

New study sheds light on how immune system functions during sleep

A new study sheds light on how the immune system replenishes itself during sleep. Researchers found that some subsets of T cells are reduced from the bloodstream during sleep when risk of infection is low. [More]
New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research has shown how the immune system avoids attacking its own tissues with antibodies - whilst still maintaining a strong defence against invaders. [More]
Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

A study led by researchers at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research, Janssen Vaccines & Prevention B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson and Gilead Sciences, Inc., has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV. [More]
Investigational treatment combination improves virologic control in SIV-infected monkeys

Investigational treatment combination improves virologic control in SIV-infected monkeys

Researchers have found that an investigational treatment combination of a therapeutic vaccine and an immune-stimulator improves virologic control and delays viral rebound following the discontinuation of antiretroviral therapy (ART) in non-human primates infected with SIV, the simian form of HIV. [More]
Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events. [More]
Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events. [More]
New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

A blood test that has shown promise in predicting how cancer will progress and what treatments will be most effective for a given patient may not be reliable for either, according to a new Penn Medicine study published this week in Cancer, a peer-reviewed journal of the American Cancer Society. [More]
New approach could overcome large immunosuppressive tumors

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality. [More]
New study examines how tumor genome testing helps improve breast cancer treatment

New study examines how tumor genome testing helps improve breast cancer treatment

A new study examines how one early example of precision medicine--tumor genome testing--is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy. [More]
New oncogene may contribute to high incidence of prostate cancer among African American men

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer. [More]
UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

While successful treatment of HIV with antiretroviral medications leads to undetectable levels of virus in the blood, controls the disease and leads to much longer lifespans, scientists know that HIV continues to reside in tissues. [More]
Hypofractionated RT can reduce treatment time by half in stage II and III NSCLC patients

Hypofractionated RT can reduce treatment time by half in stage II and III NSCLC patients

For patients with stage II and III non-small cell lung cancer (NSCLC) unable to receive standard treatments of surgery or chemoradiation (CRT), hypofractionated radiation therapy (RT) results in similar overall survival (OS) and progression-free survival (PFS) rates, limited severe side effects and shorter treatment times when compared to conventional RT, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology. [More]
Leading cancer organizations publish new guidelines on postmastectomy radiotherapy

Leading cancer organizations publish new guidelines on postmastectomy radiotherapy

Three leading national cancer organizations today issued a joint clinical practice guideline update for physicians treating women with breast cancer who have undergone a mastectomy. [More]
Study shows retinoic acid could prevent postsurgical lymphedema

Study shows retinoic acid could prevent postsurgical lymphedema

A study conducted at the Keck School of Medicine of the University of Southern California showed that 9-cis retinoic acid (alitretinoin) could significantly prevent postsurgical lymphedema. [More]
Study reveals promising strategy against bladder cancer metastasis

Study reveals promising strategy against bladder cancer metastasis

The popular kids' card game "Exploding Kittens" teaches a concept critical to cancer science: When a player plays a "Nope" card, the subsequent player may lay another "Nope", thus creating a double-negative that becomes a positive, allowing the initial action to proceed. [More]
Virginia Mason offers totally laparoscopic advanced surgery for removing tumors from pancreas

Virginia Mason offers totally laparoscopic advanced surgery for removing tumors from pancreas

Virginia Mason now offers the totally laparoscopic Whipple procedure as an advanced surgical option for removing tumors from the head of the pancreas. [More]
Research findings pave way to effective strategies for treatment of visceral leishmaniasis

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans. [More]
Genetic test may be able to predict need for chemotherapy in early-stage breast cancer

Genetic test may be able to predict need for chemotherapy in early-stage breast cancer

Patients with early stage breast cancer who have a low genetic risk of disease recurrence may not need to have chemotherapy, report researchers. [More]
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