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Research findings pave way to effective strategies for treatment of visceral leishmaniasis

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans. [More]
Genetic test may be able to predict need for chemotherapy in early-stage breast cancer

Genetic test may be able to predict need for chemotherapy in early-stage breast cancer

Patients with early stage breast cancer who have a low genetic risk of disease recurrence may not need to have chemotherapy, report researchers. [More]
Study shows lymph node stage may have clinical importance among NSCLC patients with M1a disease

Study shows lymph node stage may have clinical importance among NSCLC patients with M1a disease

Analysis of a large non-small cell lung cancer (NSCLC) patient cohort with stage IV M1a disease identified lymph node staging as having clinical significance and an impact on prognosis. [More]
Research findings could lead to new ways of preventing or treating organ transplant rejection

Research findings could lead to new ways of preventing or treating organ transplant rejection

An international team led by researchers from the University of Pittsburgh School of Medicine found that targeting certain donor cells lowered the risk of organ rejection in mice that underwent kidney and heart transplants. [More]
Study demonstrates safety and effectiveness of new SLN radiotracer in breast cancer patients

Study demonstrates safety and effectiveness of new SLN radiotracer in breast cancer patients

Determining whether breast cancer has spread to sentinel lymph nodes (SLN) is key to prognosis and treatment, making SLN mapping critical. [More]
German scientists develop new approach to prevent GvHD after bone marrow transplants

German scientists develop new approach to prevent GvHD after bone marrow transplants

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants. [More]
NIH funds collaborative project to develop better vaccine adjuvants for many diseases

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Dr. Qizhi Cathy Yao, professor of surgery, molecular virology and microbiology, and pathology & immunology at Baylor College of Medicine, has been awarded a National Institutes of Health grant to fund a collaborative project with Molecular Express, Inc. [More]
Lack of insurance may increase risk of death in men with testicular cancer, study finds

Lack of insurance may increase risk of death in men with testicular cancer, study finds

Men with testicular cancer who were uninsured or on Medicaid had a higher risk of death from what is normally a curable disease than insured patients, a new study found. [More]
Studies show insurance status may impact patients' health outcomes following cancer diagnosis

Studies show insurance status may impact patients' health outcomes following cancer diagnosis

Two new studies indicate that health insurance status may impact patients' health outcomes following a diagnosis of cancer. [More]
PD-1-responsive T cells may offer clues to design more effective drugs for cancer

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs. [More]
Researchers shed light on mechanism for inducing memory B cell differentiation

Researchers shed light on mechanism for inducing memory B cell differentiation

A group of researchers at Immunology Frontier Research Center (IFReC), Osaka University and RIKEN Center for Integrative Medical Sciences jointly clarified the mechanism for inducing germinal-center B cells' differentiation into memory B cells, immune cells that remember antigens, at the molecular level. [More]
VCU Health radiologist uses MRI technology to detect difficult prostate cancers

VCU Health radiologist uses MRI technology to detect difficult prostate cancers

For three years, Andrew Harder wondered if he had prostate cancer. In 2009, he had routine blood work that revealed an elevated prostate-specific antigen (PSA) level. [More]
New study identifies alternative route for tuberculosis infection

New study identifies alternative route for tuberculosis infection

Researchers from UT Southwestern Medical Center have identified a new way that tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore. [More]
ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer

ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer

The American Society for Radiation Oncology recently issued a new clinical practice statement, "Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method." [More]
Bone marrow transplantation may one day be beneficial to subset of ALS, say researchers

Bone marrow transplantation may one day be beneficial to subset of ALS, say researchers

Harvard Stem Cell Institute researchers at Harvard University and the Broad Institute of Harvard and MIT have found evidence that bone marrow transplantation may one day be beneficial to a subset of patients suffering from amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder more commonly known as Lou Gehrig's disease. [More]
Women who undergo axillary node surgery for breast cancer more likely to develop chronic pain

Women who undergo axillary node surgery for breast cancer more likely to develop chronic pain

An analysis led by McMaster University researchers has found that women who undergo armpit lymph node surgery for breast cancer are much more likely to develop chronic pain. [More]
Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Scientists at the Johns Hopkins Kimmel Cancer Center and University of Melbourne report they have used a genetic test that spots bits of cancer-related DNA circulating in the blood to accurately predict the likelihood of the disease's return in some — but not all — of a small group of patients with early-stage colon cancer. [More]
Researchers develop computer model for speed analysis of TB's complex life-cycle

Researchers develop computer model for speed analysis of TB's complex life-cycle

Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis, is a serious global health problem accounting for 1.3 million worldwide deaths annually. [More]
Low mammographic breast density linked to worse prognosis in breast cancer patients

Low mammographic breast density linked to worse prognosis in breast cancer patients

Even though dense breast tissue is a risk factor for breast cancer, very low mammographic breast density is associated with a worse prognosis in breast cancer patients. [More]
Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed. [More]
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