Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

UVA discoveries highlight the different roles of blood vessels in solid tumors

Two new discoveries from the Dudley lab at UVA Cancer Center highlight the different roles of blood vessels in solid tumors – and the findings could help prevent breast cancer from spreading and enhance the effectiveness of one of the most important new cancer treatments in many years.

4 Jun 2023

Novel approach improves the efficacy of immune checkpoint blockade and minimizes related side effects

Scientists at Tohoku University have discovered a novel approach that improves the efficacy of immune checkpoint blockade (ICB) - a novel form of cancer treatment utilizing immune checkpoint inhibitors (ICIs) - and minimizes the associated side effects.

1 Jun 2023

Extended lymphadenectomy for locally advanced bladder cancer provides no patient benefit

An extended lymphadenectomy – removal of additional lymph nodes beyond the extent of the standard procedure – in patients undergoing radical cystectomy (removal of bladder and nearby tissues) because of clinically localized muscle-invasive bladder cancer provides no patient benefit as measured by disease-free survival or overall survival times.

30 May 2023

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

25 May 2023

Ticks found to harbor and release prions of chronic wasting disease

Researchers determined whether ticks contain transmission-relevant amounts of chronic wasting disease.

17 May 2023

Every breath counts; Utilizing breath biopsy technology to detect disease early

In this interview, we speak to Mariana Leal, Team Lead at Owlstone Medical, about breath biopsies and how they are a useful tool for investigating biomarkers for the early detection of diseases.

From Owlstone Medical Ltd 17 May 2023

Study aims to optimize radiotherapy treatment for patients with anal cancer

Reducing the dose and duration of radiotherapy treatments for anal cancer may result in fewer side effects, recent clinical trial results have shown.

15 May 2023

Researchers establish a benchmark for gallbladder cancer surgery

The quality of surgery can drastically influence both short- and long-term postoperative outcomes and is a crucial consideration in studies that assess surgical outcomes.

8 May 2023

Lymphoma risk is slightly elevated in patients with IBD

The risk of developing lymphoma is slightly elevated in inflammatory bowel disease (IBD) and has increased in recent years in patients with Crohn's disease, report researchers from Karolinska Institutet in a study published in Clinical Gastroenterology and Hepatology.

21 Apr 2023

Study paves the way for some patients with testicular cancer to avoid chemotherapy and radiation

A newly published study paves the way for some patients with testicular cancer to avoid chemotherapy and radiation.

30 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Enhancing the effectiveness of immunization against certain cancers

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system.

27 Mar 2023

New treatment using nanoparticles can repair lymphatic vessel pumping

The human body is made up of thousands of tiny lymphatic vessels that ferry white blood cells and proteins around the body, like a superhighway of the immune system.

20 Mar 2023

Research reveals the mechanism that triggers breast cancer 'time bomb'

Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep - forming incurable secondary tumors.

13 Mar 2023

Small change to keyhole surgery for prostate cancer can reduce post-operative complications

Surgeons in Germany have shown a small technical change to keyhole surgery for prostate cancer can more than halve one of the most common post-operative complications – where lymphatic fluid collects in the pelvis.

13 Mar 2023

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

IgG4 serum levels do not show elevation in post-COVID syndrome

In a recent study posted to bioRxiv* preprint server, researchers in Germany assessed the differences in antigen-specific immunoglobulin G (IgG) subtypes between post-COVID syndrome (PCS) patients and convalescent controls.

6 Mar 2023

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Bacteria of the species Pseudomonas aeruginosa are antibiotic-resistant hospital germs that can enter blood, lungs and other tissues through wounds and cause life-threatening infections.

1 Mar 2023

HIV creates reservoirs much earlier than expected, study shows

For the first time in humans, a research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy.

28 Feb 2023

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Researchers mapped Zika virus infections in the lymph nodes to determine how the Zika virus enters from different points in the skin and disseminates through the body.

20 Feb 2023