Lymphopenia News and Research

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Lymphopenia is a condition in which there is a lower-than-normal number of lymphocytes (a type of white blood cell) in the blood. Also called lymphocytic leukopenia and lymphocytopenia.

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

A broad evaluation of autoimmune disease-associated autoantibodies that have been observed in COVID-19 patients was performed.

22 Feb 2022

Study reveals peripheral blood biomarkers able to predict COVID-19 clinical outcomes in ICU admission

A new study involved the development of an immunological biomarker screen that upon ICU admission can predict the length of ICU stay or death.

3 Feb 2022

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Minks may be a suitable animal model for testing severe COVID-19 infections, finds a recent bioRxiv* preprint study. While mice and ferrets are used in preclinical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is currently no model specific to severe disease.

30 Jan 2022

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital.

26 Jan 2022

Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

In a new study, a team of researchers developed a vaccine candidate with the SARS-CoV-2 spike (S) glycoprotein coated onto lipid vesicles which resembles virus-like particles.

26 Jan 2022

Exploring hematological alterations in COVID-19 patients

New study findings indicated that some hematological alterations that occur during COVID-19-related hospital admission were associated with an increase in the risk of COVID-19-associated ICU admission and mortality.

26 Jan 2022

Understanding immune responses to SARS-CoV-2 infections in children

A study published in the journal Immunity analyzed the varied manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children.

26 Jan 2022

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

A new study revealed that the expression of HERV-W envelope protein (ENV) in lymphoid cells from COVID-19 patients correlated with disease outcome making them biomarkers of lymphocyte exhaustion.

24 Jan 2022

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Researchers examine the effects of disease-modifying therapies implemented for treating multiple sclerosis on the immune response to SARS-CoV-2 infection.

12 Jan 2022

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

The first study to evaluate the clinical characteristics and outcomes of fully vaccinated patients with cancer who had breakthrough COVID-19 infections indicates they remained at high risk for hospitalization and death.

26 Dec 2021

New approach to COVID-19 immune profiling using blood-based machine learning

A new study discusses the application of a novel deconvolution model AImmune to predict moderate and severe cases of COVID-19.

5 Dec 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

An investigation of SARS-CoV-2 infection in diabetic pregnancies

Researchers discuss the basic and clinical science of the potential inter-relationships between diabetes mellitus and COVID-19 in pregnancies.

11 Oct 2021

Better clinical outcomes in COVID-19 and vaccine-related myocarditis than classic myocarditis in children

Researchers have investigated the differences between 'classic' myocarditis, COVID-19 induced myocarditis, and vaccine-related myocarditis.

11 Oct 2021

Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients

In this review, researchers summarized the therapeutic and pathogenic role of IL-7 in patients with COVID-19 and examined the promising role of IL-7 as a vaccine adjuvant.

7 Oct 2021

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

A recent study discusses the rate of changes in peripheral blood white cells in individuals who have recovered from SARS-CoV-2 infection.

3 Oct 2021

SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

French researchers used a highly sensitive and specific nucleocapsid-Ag assay to explore the relationship between N-Ag in urine during COVID-19 and the severity of the disease in hospitalized patients.

30 Sep 2021

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Now, in a new news study posted to the bioRxiv* preprint server, researchers have successfully induced similar chronicity associated with SARS-CoV-2 infection in MISTRG6-hACE2 humanized mice.

29 Sep 2021

Study: Nearly one in five patients with malignant pleural mesothelioma contracted COVID-19

Nearly one in five patients with malignant pleural mesothelioma (MPM) at a Barcelona hospital contracted COVID-19 during the pandemic.

8 Sep 2021

Lymphopenia News and Research

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

Study reveals peripheral blood biomarkers able to predict COVID-19 clinical outcomes in ICU admission

Research shows minks mimic severe COVID-19 symptoms, including ARDS

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

Exploring hematological alterations in COVID-19 patients

Understanding immune responses to SARS-CoV-2 infections in children

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

New approach to COVID-19 immune profiling using blood-based machine learning

Current understanding of the link between COVID-19 and cardiovascular disease

How long does natural or vaccine-induced immunity to COVID last?

An investigation of SARS-CoV-2 infection in diabetic pregnancies

Better clinical outcomes in COVID-19 and vaccine-related myocarditis than classic myocarditis in children

Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Study: Nearly one in five patients with malignant pleural mesothelioma contracted COVID-19

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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