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Myriad myRisk test solves overlap dilemma between hereditary cancer syndromes

Myriad myRisk test solves overlap dilemma between hereditary cancer syndromes

Myriad Genetics, Inc. today presented several clinical studies on the Myriad myRisk- Hereditary Cancer test at the 2014 American Society of Clinical Oncology annual meeting in Chicago, Illinois. [More]
Memorial Sloan Kettering Cancer Center, Quest Diagnostics partner for cancer tests

Memorial Sloan Kettering Cancer Center, Quest Diagnostics partner for cancer tests

Memorial Sloan Kettering Cancer Center, the world's oldest and largest private cancer center, and Quest Diagnostics, the world's leading provider of diagnostic information services, today announced a joint collaboration that will utilize MSK's clinical and research insights into gene mutations associated with solid tumors. [More]
Pathway Genomics announces launch of Hereditary Colorectal Cancer DNA Insight genetic test

Pathway Genomics announces launch of Hereditary Colorectal Cancer DNA Insight genetic test

Pathway Genomics Corporation, a San Diego-based CLIA and CAP accredited clinical laboratory that offers genetic testing services worldwide, today announced the launch of Hereditary Colorectal Cancer DNA Insight, the company's premier hereditary cancer genetic test. Based on a simple saliva sample, the test uses next-generation sequencing (NGS) technology to identify gene alterations or mutations that increase a patient's risk of developing certain types of cancer. [More]
International study develops refined method to identify individuals at risk for certain inherited cancer

International study develops refined method to identify individuals at risk for certain inherited cancer

An international study has developed a refined method to identify people at risk for certain inherited cancer as a result of Lynch syndrome. [More]
Report: Screen all endometrial cancer patients for Lynch syndrome

Report: Screen all endometrial cancer patients for Lynch syndrome

A recent article by Norris Cotton Cancer Center researchers published in the January 2014 issue of the journal Clinical Chemistry reviews the scientific evidence that warrants screening all endometrial cancers for Lynch syndrome. Next to colorectal cancer, endometrial cancer is the most common form of cancer in women with Lynch syndrome. [More]
Pathway Genomics, Susan G. Komen to educate women about breast cancer screening

Pathway Genomics, Susan G. Komen to educate women about breast cancer screening

Pathway Genomics and Susan G. Komen, the largest source of nonprofit funds dedicated to the fight against breast cancer, have announced a partnership to educate women about the screening options available to detect a predisposition to breast cancer. [More]
Genetic testing for cancer-causing mutations in affected families is very low, study finds

Genetic testing for cancer-causing mutations in affected families is very low, study finds

A new study of the use of genetic testing for cancer-causing mutations in affected families in France has found that its take-up is very low. [More]
Lynch syndrome and cancer risk: an interview with Prof. Ellen Kampman, Wageningen University

Lynch syndrome and cancer risk: an interview with Prof. Ellen Kampman, Wageningen University

Lynch syndrome is one of the inherited cancer syndromes characterized by the development of colorectal cancer, endometrial cancer and other cancers at an early age. [More]
Men with Lynch syndrome face increased lifetime risk of prostate cancer

Men with Lynch syndrome face increased lifetime risk of prostate cancer

Men with an inherited genetic condition called Lynch syndrome face a higher lifetime risk of developing prostate cancer and appear to develop the disease at an earlier age, according to a new study led by researchers at the University of Michigan Comprehensive Cancer Center. [More]
Screening healthy adults could potentially prevent rare genetic disorders

Screening healthy adults could potentially prevent rare genetic disorders

Millions of people unknowingly carry rare gene mutations that put them at high risk of developing preventable diseases such as colorectal cancer, breast cancer, and several catastrophic blood vessel disorders. [More]
Colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome

Colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome

Cleveland Clinic researchers have found that colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome, the most common hereditary, adult-onset cause of colorectal cancer, as published in the online version of the Journal of Clinical Oncology. [More]
New method based on mass sequencing can detect hereditary breast and ovarian cancer syndrome

New method based on mass sequencing can detect hereditary breast and ovarian cancer syndrome

Researchers of the Catalan Institute of Oncology (ICO) at the Bellvitge Biomedical Research Institute (IDIBELL) have developed and validated a new method to diagnose hereditary breast and ovarian cancer syndrome based on mass sequencing of BRCA1 and BRCA2 genes. The model is based on a genetic and bioinformatic analysis which has been proved very effective. [More]
Loading up on snack foods may increase cancer risk in individuals with Lynch syndrome

Loading up on snack foods may increase cancer risk in individuals with Lynch syndrome

A new analysis has found that loading up on snack foods may increase cancer risk in individuals with an inborn susceptibility to colorectal and other cancers. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that an eating pattern low in snack foods could help these individuals-who have a condition called Lynch syndrome-lower their risk. [More]
Colon cancer risk: Supplements no substitute for dietary fiber

Colon cancer risk: Supplements no substitute for dietary fiber

Dietary supplementation with resistant starch does not reduce long-term colorectal cancer risk in patients with Lynch syndrome, shows the CAPP2 study. [More]
Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance." [More]
Universal tumor testing superior to selective strategy in identifying Lynch syndrome among CRC patients

Universal tumor testing superior to selective strategy in identifying Lynch syndrome among CRC patients

In a comparison of strategies to identify individuals with Lynch syndrome, the most common form of hereditary colorectal cancer (CRC), caused by mutations in certain genes (DNA mismatch repair [MMR] genes), universal tumor MMR testing among certain CRC patients had a greater sensitivity for the identification of Lynch syndrome compared with multiple alternative strategies, although the diagnostic improvement was modest, according to a study in the October 17 issue of JAMA. [More]
High costs can limit access to potentially life-saving technology

High costs can limit access to potentially life-saving technology

More than one-fifth of people who have received referrals to test for cancer-causing genes say they will only undergo testing if their insurance covers the cost-just as more insurers are instituting cost-sharing for medical services like genetic testing, according to new findings from Fox Chase Cancer Center in Philadelphia released at this year's 2012 Annual Meeting of the American Society of Clinical Oncology on Saturday, June 2. [More]
Gastroenterologists provide five facts to reduce colon cancer risk

Gastroenterologists provide five facts to reduce colon cancer risk

The number two cancer killer in the U.S. is often preventable and highly curable. "It's important for people to understand that, with proper screening, colon cancer can not only be detected early, but often can be prevented from developing," says Dr. Felice Schnoll-Sussman, a gastroenterologist and acting director of The Jay Monahan Center for Gastrointestinal Health at NewYork-Presbyterian/Weill Cornell Medical Center. [More]
Study confirms increased risk of cancers linked with Lynch syndrome

Study confirms increased risk of cancers linked with Lynch syndrome

People with Lynch syndrome have a genetic mutation that gives them a high risk of several types of cancer including bowel cancer. The genes that are damaged can't repair any errors that occur in our DNA. [More]
People with Lynch syndrome face increased risks of breast and pancreatic cancers

People with Lynch syndrome face increased risks of breast and pancreatic cancers

A new prospective study of patients with Lynch syndrome - an inherited disorder of cancer susceptibility caused by mutations in specific DNA repair genes - provides the first strong evidence that people with Lynch syndrome face significantly increased risks of breast and pancreatic cancers. [More]