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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Correlation of antibody titers with COVID-19 vaccine efficacy

In a new study the relationship between virus-neutralizing antibody and spike protein-binding IgG antibody levels is explored following vaccination by one of seven currently deployed vaccines. The findings support the use of antibody titers as correlates of protection for COVID-19 vaccines.

23 Mar 2021

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

Although Tuberculosis, or TB, killed nearly as many people as COVID-19 (approx. 1.8 million) in 2020, it did not receive as much media and public attention.

22 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

Anti-inflammatory therapies may help prevent heart disease in people with age-related blood condition

Therapies that soothe inflammation could be an effective way to prevent heart disease in people with a common age-related blood condition, according to a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons.

18 Mar 2021

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

The triggers and causes of a severe scarring disease of the lungs -- idiopathic pulmonary fibrosis, or IPF -- remain unclear.

18 Mar 2021

Researchers explore potential role of TARM1 protein in pathogenesis of rheumatoid arthritis

TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models.

17 Mar 2021

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

The COVID-19 pandemic has claimed over 2.67 million lives in less than a year and a half. However, it is uncommon in children, with less than 2% of the cases being in individuals below the age of 19. Most of these are of mild severity, with the clinical features of severe COVID-19 being rare in this age group.

17 Mar 2021

Researchers develop innovative profiling methods for SARS-CoV-2 infection

A team of researchers from various institutions in the USA used RNA-sequencing data and other methods to profile unique genes and other characteristics associated with SARS-CoV-2 in New York City (NYC).

17 Mar 2021

UTHSC professor awarded $1.79 million grant to develop new amyloidosis treatment

The National Institute of Diabetes and Digestive and Kidney Diseases recently awarded Jonathan Wall, PhD, professor in the University of Tennessee Health Science Center's Graduate School of Medicine in Knoxville, a $1.79 million grant for his study titled "Developing a Theranostic Immunotherapy for Systemic Amyloidosis."

16 Mar 2021

Scientists discover how novel pathogens promote colorectal cancer development

Do BMMFs, the novel infectious agents found in dairy products and bovine sera, play a role in the development of colorectal cancer? Scientists led by Harald zur Hausen detected the pathogens in colorectal cancer patients in close proximity to tumors.

15 Mar 2021

The role of nanotechnology in the fight against COVID-19

Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse nanomaterials (polymeric, inorganic self-assembling materials and peptide-based) towards COVID-19 prevention, diagnosis and therapy.

15 Mar 2021

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

In a recent bioRxiv preprint research paper, Botond Z. Igyártó and colleagues from Thomas Jefferson University demonstrated the inflammatory nature of the lipid nanoparticles (LNPs).

15 Mar 2021

Researchers discover new protein that may play a key role in atherosclerosis

Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis.

11 Mar 2021

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

In the last two decades, immunotherapy has emerged as a leading treatment for advanced renal carcinoma cancer (more commonly known as kidney cancer).

11 Mar 2021

SARS-CoV-2 can infect blood monocytes and trigger inflammation, finds study

Researchers found about 10% of blood monocytes in coronavirus disease 2019 (COVID-19) patients are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These monocytes then die, leading to the release of cytokines – a feature associated with severe and critical COVID-19.

11 Mar 2021

Study shows macrophages cause excess scarring after surgery

The body is amazing at healing itself. However, sometimes it can overdo it. Excess scarring after abdominal and pelvic surgery within the peritoneal cavity can lead to serious complications and sometimes death.

8 Mar 2021

Researchers discover how adhesions form in the abdomen

Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form.

5 Mar 2021

Discovery offers a precise route to treat inflammation associated with neuropathic pain

One of the hallmarks of chronic pain is inflammation, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1+ macrophages are dysfunctional in an animal model of neuropathic pain.

5 Mar 2021

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

A new study reports the potential of the cell surface marker, CD47, as a biomarker for hyperinflammation, a characteristic feature of severe COVID-19.

4 Mar 2021

Macrophage News and Research

Further Reading

Correlation of antibody titers with COVID-19 vaccine efficacy

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

Male fertility and androgen production may be impacted by COVID-19

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Anti-inflammatory therapies may help prevent heart disease in people with age-related blood condition

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

Researchers explore potential role of TARM1 protein in pathogenesis of rheumatoid arthritis

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

Researchers develop innovative profiling methods for SARS-CoV-2 infection

UTHSC professor awarded $1.79 million grant to develop new amyloidosis treatment

Scientists discover how novel pathogens promote colorectal cancer development

The role of nanotechnology in the fight against COVID-19

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

Researchers discover new protein that may play a key role in atherosclerosis

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

SARS-CoV-2 can infect blood monocytes and trigger inflammation, finds study

Study shows macrophages cause excess scarring after surgery

Researchers discover how adhesions form in the abdomen

Discovery offers a precise route to treat inflammation associated with neuropathic pain

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

Microbiology eBook

Expanding research and clinical options for children with cancer

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