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AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

Scientists have proposed that inflammation is the harbinger of aging and central to the aging process, a phenomenon described as 'inflamm-aging,' said Dr. Yuxiang Sun. [More]
Research finding opens door to new treatment options for inflammatory rheumatism

Research finding opens door to new treatment options for inflammatory rheumatism

Enthesitis, inflammation of tendons where they attach to the bone, is a common medical problem which underlies various forms of inflammatory rheumatism. [More]
NYIT researcher aims to study link between wound healing problems and methamphetamine use

NYIT researcher aims to study link between wound healing problems and methamphetamine use

A chance observation in a Southern California fast food restaurant led Luis Martinez, Ph.D., to wonder about the connections behind wound healing problems and methamphetamine use. [More]
Researchers find reason behind epidemiological success of Russian tuberculosis strains

Researchers find reason behind epidemiological success of Russian tuberculosis strains

Researchers from the Federal Research and Clinical Centre of Physical-Chemical Medicine, and staff from MIPT's Systems Biology Laboratory, the Research Institute of Phthisiopulmonology and the St. Petersburg Pasteur Institute, conducted a large-scale analysis of the proteins and genomes of mycobacterium tuberculosis strains that are common in Russia and countries of the former Soviet Union and found features that provide a possible explanation for their epidemiological success. [More]
MSU scientists show how special genes stay open to fight against infections

MSU scientists show how special genes stay open to fight against infections

A new discovery at Michigan State University has revealed how special genes stay open for business, helping diagram a mechanism that plays a key role in fighting inflammation and infections. [More]
Researchers explain why secondary infection with MRSA kills influenza patients

Researchers explain why secondary infection with MRSA kills influenza patients

Researchers have discovered that secondary infection with the Methicillin-resistant Staphylococcus aureus (MRSA) bacterium (or "superbug") often kills influenza patients because the flu virus alters the antibacterial response of white blood cells, causing them to damage the patients' lungs instead of destroying the bacterium. [More]
Scientists identify potential mechanism that paves way for improved treatment of fungal infections

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments. [More]
Antioxidant compound could be effective to combat immune rejection after islet transplantation

Antioxidant compound could be effective to combat immune rejection after islet transplantation

A team of researchers has found that doses of bilirubin help provide suppression of the immune response following islet transplantation in mouse models. [More]
Heart-resident macrophages promote neutrophil recruitment after ischemic injury

Heart-resident macrophages promote neutrophil recruitment after ischemic injury

Tissue injury, such as occurs in response to a lack of oxygen, promotes an influx of immune cells to the site of damage. [More]
E. coli K1 inhibits glucose transporters during meningitis, report scientists

E. coli K1 inhibits glucose transporters during meningitis, report scientists

Escherichia coli K1 (E. coli K1) continues to be a major threat to the health of young infants. Affecting the central nervous system, it causes neonatal meningitis by multiplying in immune cells, such as macrophages, and then disseminating into the bloodstream to subsequently invade the blood-brain barrier. [More]
Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis. [More]
UCI molecular biologists find new way to combat skin cancer

UCI molecular biologists find new way to combat skin cancer

Using new and innovative immune-therapeutic approaches to silence "don't eat me" signaling proteins recognized by specialized cells of the immune system, University of California, Irvine molecular biologists and their colleagues have identified an effective way to combat metastatic melanoma. [More]
Researchers identify how precise control of inflammation could lead to bone repair

Researchers identify how precise control of inflammation could lead to bone repair

In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair. [More]
Researchers uncover novel virulence strategies employed by Leishmania parasite

Researchers uncover novel virulence strategies employed by Leishmania parasite

Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite. [More]
Good ceramides in skin creams and shampoos may hold promise for Alzheimer's treatment

Good ceramides in skin creams and shampoos may hold promise for Alzheimer's treatment

The best-selling lipid in the world, often prominently featured on skin cream and shampoo labels, appears to also hold promise for Alzheimer's treatment, scientists say. [More]
New study identifies alternative route for tuberculosis infection

New study identifies alternative route for tuberculosis infection

Researchers from UT Southwestern Medical Center have identified a new way that tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore. [More]
Scientists discover promising approach to combat life-threatening bacterial infections without antibiotics

Scientists discover promising approach to combat life-threatening bacterial infections without antibiotics

Patients suffering from liver cirrhosis often die of life-threatening bacterial infections. In these patients the immune cells are unable to eliminate the bacterial infections. [More]
Researchers demonstrate important functional role of lincRNA in immune system

Researchers demonstrate important functional role of lincRNA in immune system

A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School. [More]
Scientists discover new mechanism by which TNF protects against intracellular pathogens

Scientists discover new mechanism by which TNF protects against intracellular pathogens

Tumour necrosis factor (TNF), a messenger substance in the immune system, plays an important role in triggering chronic inflammatory diseases. For this reason, TNF inhibitors are a standard form of treatment for patients with rheumatoid arthritis and certain inflammatory bowel diseases. [More]
Studies shed more light on relation between bacteria, immune system and antibiotics

Studies shed more light on relation between bacteria, immune system and antibiotics

Antibiotics and the immune system are the two forces that cope with bacterial infections. Now, two studies from Isabel Gordo's laboratory, at Instituto Gulbenkian de Ciência, show for the first time that resistance to antibiotics and to the immune system is interconnected in bacteria. [More]
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