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Deben reports on the work of the Microscopy & Histology Core Facility at the University of Aberdeen

Deben reports on the work of the Microscopy & Histology Core Facility at the University of Aberdeen

Deben reports on the work of the Microscopy & Histology Core Facility at the University of Aberdeen where a newly installed TEM and camera system have enhanced the services provided to users. [More]
UNC researchers use exosomes to deliver potent Parkinson's treatment directly to the brain

UNC researchers use exosomes to deliver potent Parkinson's treatment directly to the brain

Researchers at the University of North Carolina at Chapel Hill have used exosomes -- tiny bubbles of protein and fat produced naturally by cells -- to bypass the body's defenses and deliver a potent antioxidant directly to the brain to treat Parkinson's disease. [More]
Researchers describe critical connection associated with environmental cause of silicosis, lung cancer

Researchers describe critical connection associated with environmental cause of silicosis, lung cancer

Researchers at the University of Louisville have detailed a critical connection associated with a major environmental cause of silicosis and a form of lung cancer. Their study is reported in today's Nature Communications. [More]
UVA research identifies new role of immune system in Rett syndrome

UVA research identifies new role of immune system in Rett syndrome

The immune system is designed to protect us from disease. But what if it was malfunctioning? Would it make a disease worse? That appears to be the case with Rett syndrome, a neurodevelopmental disorder, and possibly in other neurological disorders as well, new research from the University of Virginia School of Medicine has found. [More]
Novel approach allows real-time imaging of ongoing immune response

Novel approach allows real-time imaging of ongoing immune response

A novel approach that allows real-time imaging of the immune system's response to the presence of tumors—without the need for blood draws or invasive biopsies—offers a potential breakthrough both in diagnostics and in the ability to monitor efficacy of cancer therapies. [More]
MGH investigators identify inflammatory molecule that plays key role in lupus

MGH investigators identify inflammatory molecule that plays key role in lupus

Massachusetts General Hospital (MGH) investigators have identified an inflammatory molecule that appears to play an essential role in the autoimmune disorder systemic lupus erythematosus, commonly known as lupus. [More]
Nanomedicine strategy can help reduce heart attacks, strokes

Nanomedicine strategy can help reduce heart attacks, strokes

A research team showed that a nanotherapeutic medicine can halt the growth of artery plaque cells resulting in the fast reduction of the inflammation that may cause a heart attack, according to a study led by researchers from Icahn School of Medicine at Mount Sinai and published April 3 in Science Advances. [More]
Peripheral inflammatory cells play role in Parkinson's disease

Peripheral inflammatory cells play role in Parkinson's disease

A small area in the midbrain known as the substantia nigra is the control center for all bodily movement. Increasing loss of dopamine-generating neurons in this part of the brain therefore leads to the main symptoms of Parkinson's disease - slowness of movement, rigidity and shaking. [More]
MRSA bacteria exposed to cigarette smoke become more resistant to antimicrobial peptides

MRSA bacteria exposed to cigarette smoke become more resistant to antimicrobial peptides

Methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant superbug, can cause life-threatening skin, bloodstream and surgical site infections or pneumonia. Researchers at the University of California, San Diego School of Medicine now report that cigarette smoke may make matters worse. [More]
Low doses of imatinib drug can push immune system to combat bacterial infections

Low doses of imatinib drug can push immune system to combat bacterial infections

Low doses of the anti-cancer drug imatinib can spur the bone marrow to produce more innate immune cells to fight against bacterial infections, Emory researchers have found. [More]
New research reveals how a deadly fungus grows and kills immune cells

New research reveals how a deadly fungus grows and kills immune cells

New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most common causes of bloodstream infections. [More]
Keystone meeting focuses on neuroinflammation, Alzheimer's and other neurodegenerative diseases

Keystone meeting focuses on neuroinflammation, Alzheimer's and other neurodegenerative diseases

As Alzheimer's disease sweeps through the brain, do the brain's immune cells sit idly by and let it happen? Or could they overreact and make the disease worse? [More]
Discovery may lead to new potential treatment for drug-resistant melanoma

Discovery may lead to new potential treatment for drug-resistant melanoma

In the last several years, targeted therapies - drugs that directly impact specific genes and proteins involved in the progression of cancer - have been approved for a wide variety of cancers, including melanoma, the deadliest form of skin cancer. Now, researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments. [More]
Vitamin D plays major role in preventing diabetes and atherosclerosis

Vitamin D plays major role in preventing diabetes and atherosclerosis

In recent years, a deficiency of vitamin D has been linked to type 2 diabetes and heart disease, two illnesses that commonly occur together and are the most common cause of illness and death in Western countries. Both disorders are rooted in chronic inflammation, which leads to insulin resistance and the buildup of artery-clogging plaque. [More]
New range of purified, soluble immunoreceptors announced by AMSBIO

New range of purified, soluble immunoreceptors announced by AMSBIO

AMSBIO has announced a new range of purified, soluble immunoreceptors involved in key signalling pathways. Together with new indoleamine 2,3-dioxygenase (IDO) assay kits these products that can be used to screen for inhibitors of protein-protein interaction, as well as neutralizing antibodies that serve as positive controls for inhibition. [More]
Researchers discover new metabolic mechanisms linked to macrophage polarization

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task. [More]
New vaccine for post exposure treatment of rabies infection enters human clinical trial

New vaccine for post exposure treatment of rabies infection enters human clinical trial

Yisheng Biopharma Co., Ltd., a biopharmaceutical company focusing on the research, development, manufacturing, sales and marketing of vaccine products, announced that a new vaccine for the post exposure treatment of the rabies infection was entering human clinical trial after a six-year long collaboration with a number of research institutes worldwide. [More]
Salt may help control infection

Salt may help control infection

Researchers at Vanderbilt University and in Germany have found that sodium - salt - accumulates in the skin and tissue in humans and mice to help control infection. [More]

Toning down TREM2 receptor's activity may help prevent neurodegeneration in AD patients

Tackling brain inflammation ameliorates Alzheimer's disease (AD), according to a study published in The Journal of Experimental Medicine. [More]
Rigel, Bristol-Myers Squibb partner to develop, commercialize TGF beta receptor kinase inhibitors

Rigel, Bristol-Myers Squibb partner to develop, commercialize TGF beta receptor kinase inhibitors

Rigel Pharmaceuticals, Inc. and Bristol-Myers Squibb Company today announced that they have entered into a collaboration agreement for the discovery, development and commercialization of cancer immunotherapies based on Rigel's extensive portfolio of small molecule TGF beta receptor kinase inhibitors. [More]
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