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Scientists identify how early responses of immune system can affect development of EBOV disease

Scientists identify how early responses of immune system can affect development of EBOV disease

A new mouse model of early Ebola virus infection has shown National Institutes of Health (NIH) scientists and colleagues how early responses of the immune system can affect development of EBOV disease. [More]

DGIST researchers discover mechanisms of inflammation-induced aging in animals

DGIST's research team has experimentally proved the hypothesis that the accumulated chronic inflammation results in the aging of animals. [More]
Every meal triggers short-term inflammatory responses in healthy individuals

Every meal triggers short-term inflammatory responses in healthy individuals

When we eat, we do not just take in nutrients - we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria. [More]
Researchers discover underlying cause for formation of granulomas

Researchers discover underlying cause for formation of granulomas

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs. [More]
Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic. [More]
Targeting Legumain could be promising strategy for treatment of cancer

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease. [More]
Scientists pinpoint specific molecular events that may cause allergic reactions to air pollution

Scientists pinpoint specific molecular events that may cause allergic reactions to air pollution

Scientists at the Immunology Frontier Research Center at Osaka University, Japan have pinpointed a specific molecular events that could explain allergic reactions to air pollution. [More]
Researchers use DNA markers to differentiate harmless species from deadly bacteria

Researchers use DNA markers to differentiate harmless species from deadly bacteria

The virulent pathogen that causes the disease tularemia, or "rabbit fever," was weaponized during past world wars and is considered a potential bioweapon. [More]
Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

A Kobe University research team has pinpointed the mechanism underlying astrocyte-mediated restoration of brain tissue after an injury. This could lead to new treatments that encourage regeneration by limiting damage to neurons incurred by reduced blood supply or trauma. [More]
ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX an innovative biotechnology company targeting the immune system to eliminate viral disease, announced today that the Company presented new preclinical data on ABX464, ABIVAX's first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART scientific conference in Los Cabos, Mexico. [More]
Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

In a new study, researchers have modified a rabies virus, so that it has a protein from the MERS virus; this altered virus works as a 2-for-1 vaccine that protects mice against both Middle East Respiratory Syndrome (MERS) and rabies. [More]
Research unlocks potential new therapies for inflammatory diseases

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue. [More]
Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks. [More]
Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered. [More]
Study uncovers mechanism that causes chemo resistance of pancreatic cancer cells

Study uncovers mechanism that causes chemo resistance of pancreatic cancer cells

A pioneering University of Liverpool research team have published a study that identifies the mechanism in the human body that causes resistance of pancreatic cancer cells to chemotherapy. [More]
Würzburg researchers develop novel technique to provide new insight into Salmonella infection process

Würzburg researchers develop novel technique to provide new insight into Salmonella infection process

Technological advances are making the analysis of single bacterial infected human cells feasible, Würzburg researchers have used this technology to provide new insight into the Salmonella infection process. [More]
New research shows immune paralysis in sepsis patients can be reversed

New research shows immune paralysis in sepsis patients can be reversed

Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar. [More]
Getting drugs to bugs in NTM lung infections: an interview with Dr Jakko van Ingen

Getting drugs to bugs in NTM lung infections: an interview with Dr Jakko van Ingen

The first thing that is important to stress is that this is an area that we actually know very little about. What we generally think, rather than know, is that NTM has a lot in common with pulmonary tuberculosis. [More]
TSRI study suggests new approach to limit tumor growth by targeting immune system cells

TSRI study suggests new approach to limit tumor growth by targeting immune system cells

A new study led by scientists at The Scripps Research Institute suggests there may be a way to limit tumor growth by targeting immune system cells called macrophages. [More]
Vaccine-related rubella virus causes harm in some patients with primary immunodeficiency disorders

Vaccine-related rubella virus causes harm in some patients with primary immunodeficiency disorders

Some patients with rare primary immunodeficiency disorders may be at risk for infection by rubella virus, and possibly serious skin inflammation, after receiving the rubella vaccine, usually administered as part of the measles-mumps-rubella (MMR) vaccine. [More]
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