Macular Degeneration

Macular degeneration is a disease associated with aging that gradually destroys sharp, central vision. Central vision is needed for seeing objects clearly and for common daily tasks such as reading and driving.

What is Macular Degeneration?

This is also called age-related macular degeneration (AMD), as the major risk factor for this is aging. It is an eye disorder characterized by a number of conditions negatively affecting the macula.

What Causes Macular Degeneration?

Macular Degeneration Symptoms

Macular Degeneration Treatment

Retinal Drusen

Submacular Hemorrhage (SMH)

Treatment of Submacular Hemorrhage

What is Age-Related Macular Degeneration?

Latest Macular Degeneration News and Research

Minocycline fails to slow vision loss in people with dry age-related macular degeneration

The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health.

22 Mar 2024

New AI model accurately identifies tumors and diseases in medical images

Medical diagnostics expert, doctor's assistant, and cartographer are all fair titles for an artificial intelligence model developed by researchers at the Beckman Institute for Advanced Science and Technology.

4 Mar 2024

Targeting the Hippo signaling pathway to treat systemic sclerosis

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.

21 Feb 2024

Breakthrough $20 million OCT project aims to revolutionize eye health screening

In the United States, more than one-fourth of adults over age 40 have an eye disease, including glaucoma, cataracts or age-related macular degeneration, or a chronic health condition that affects the eyes, such as diabetic retinopathy.

14 Feb 2024

New treatment targeting aging cells could offer lasting relief for diabetic macular edema

Targeting senescent cells in the retina with a BCL-xL inhibitor shows promise as a durable treatment for diabetic macular edema, potentially offering long-term visual function improvements.

8 Feb 2024

MACUSTAR extends Europe-wide clinical study on intermediate age-related macular degeneration

The MACUSTAR consortium is extending the duration of a Europe-wide clinical study on age-related macular degeneration (AMD) under the coordination of the Department of Ophthalmology at the University Hospital Bonn (UKB).

2 Feb 2024

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

1 Feb 2024

New approach offers hope for regaining lost memories in Alzheimer's

While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory.

1 Feb 2024

Genomics meets retinal imaging: A powerful fusion can predict future health

The retina is said to provide a window into a person's systemic health. In a new study published January 24th in Science Translational Medicine, physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, and the Broad Institute of MIT and Harvard combined retinal imaging, genetics and big data to estimate how likely a person is to develop eye and systemic diseases in the future.

24 Jan 2024

America’s health system isn’t ready for the surge of seniors with disabilities

The number of older adults with disabilities — difficulty with walking, seeing, hearing, memory, cognition, or performing daily tasks such as bathing or using the bathroom — will soar in the decades ahead, as baby boomers enter their 70s, 80s, and 90s.

17 Jan 2024

Night-time artificial light exposure linked to increased risk of age-related macular degeneration

A study in South Korea finds that higher exposure to outdoor artificial light at night significantly increases the risk of developing exudative age-related macular degeneration.

16 Jan 2024

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins-;and ultimately affect aging.

4 Jan 2024

AI Integration in the Fight Against Age-Related Macular Degeneration

In this interview, Wen Hwa Lee, CEO, and Chief Scientist at Action Against Age-Related Macular Degeneration (AAAMD), offers an enlightening perspective on merging AI with ophthalmology to forge new paths in healthcare and drug discovery.

From ELRIG (UK) Ltd. 3 Jan 2024

Targeted ocular spectroscopy shines new light on retinal health

Study demonstrates the effectiveness of targeted ocular fluorescence spectroscopy for analyzing the eye fundus, offering potential advancements in diagnosing and treating eye diseases.

1 Jan 2024

Champagne cork related eye injuries can be a substantial threat to eye health

Be careful this holiday season, warn researchers in the Christmas issue of The BMJ. Eye injuries while opening bottles of fizz can be significant and easily avoided.

21 Dec 2023

Machine learning predicts the long-term future of shortsighted eyes

Machine learning has been found to predict well the outcomes of many health conditions. Now, researchers from Japan have found a way to predict whether people with severe shortsightedness will have good or bad vision in the future.

13 Dec 2023

Researchers develop state-of-the-art UV protective contact lenses

The global rise in ocular diseases, largely due to insufficient ophthalmic diagnostics and monitoring, has emphasized the need for better treatment methods. Pioneering developments in therapeutic and diagnostic contact lenses are now offering hope in treating these diseases.

27 Nov 2023