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Malaria is a mosquito-borne disease caused by a parasite called Plasmodium - when infected mosquitoes bite the human body, the parasites multiply in the liver, and then infect red blood cells. Even though this potentially fatal disease can be prevented and cured, each year 350-500 million cases of malaria still occur worldwide, and over one million people die, most of them young children in Africa south of the Sahara, where one in every five (20%) childhood deaths is due to the effects of the disease.

Malaria is so common in Africa because a lack of resources and political instability have prevented the building of solid malaria control programs. Experts say an African child has on average between 1.6 and 5.4 episodes of malaria fever each year and according to the World Health Organization (WHO) as many as half of the world's population are at risk of malaria mainly in the world's poorest and most vulnerable countries and every 30 seconds a child dies from malaria.
International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

A candidate Ebola vaccine could be given to healthy volunteers in the UK, The Gambia and Mali as early as September, as part of an series of safety trials of potential vaccines aimed at preventing the disease that has killed more than 1,400 people in the current outbreak in West Africa. [More]
Experts call for action to prevent health risks associated with climate change

Experts call for action to prevent health risks associated with climate change

Previously unrecognized health benefits could be realized from fast action to reduce climate change and its consequences. For example, changes in energy and transport policies could save millions of lives annually from diseases caused by high levels of air pollution. The right energy and transport policies could also reduce the burden of disease associated with physical inactivity and traffic injury. [More]
Scientists identify number of compounds to treat cancer could add to anti-malarial arsenal

Scientists identify number of compounds to treat cancer could add to anti-malarial arsenal

Scientists searching for new drugs to fight malaria have identified a number of compounds -- some of which are currently in clinical trials to treat cancer -- that could add to the anti-malarial arsenal. [More]
Three commonly used NSAIDs affect cell membranes, produce unwanted side effects

Three commonly used NSAIDs affect cell membranes, produce unwanted side effects

Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses and/or for long periods of time, these prescription-level NSAIDs and other drugs that affect the membrane may produce wide-ranging and unwanted side effects. [More]
Novel "man and machine" decision support system for diagnosing malaria infection

Novel "man and machine" decision support system for diagnosing malaria infection

A Finnish-Swedish research group at the Institute for Molecular Medicine Finland (FIMM), University of Helsinki, and Karolinska institutet, Stockholm, has developed a novel "man and machine" decision support system for diagnosing malaria infection. [More]
Prenatal care for pregnant women increases from 61 to 91.3%, highlights Equatorial Guinea

Prenatal care for pregnant women increases from 61 to 91.3%, highlights Equatorial Guinea

Equatorial Guinea's infant mortality rate has decreased from 111 in 1994 to 65 per one thousand in 2011, said the country's Health Secretary of State, Maria del Carmen Andeme Ela. She also reported that the percentage of pregnant women receiving prenatal care from skilled health personnel has increase from 61% in 2000 to 91.3% this year. [More]

Researchers use optical tweezers to measure how strongly parasites adhere to red blood cells

Malaria is a life-threatening disease caused by a parasite that invades one red blood cell after another. Little is known about this infection process because it happens so quickly, potentially explaining why there is currently no approved malaria vaccine. [More]
Sanofi, PATH announce delivery of first large-scale batches of antimalarial treatments

Sanofi, PATH announce delivery of first large-scale batches of antimalarial treatments

Sanofi and PATH today announced the delivery of the first large-scale batches of antimalarial treatments manufactured with a new semisynthetic artemisinin derivative to malaria-endemic countries in Africa. [More]
GenVec reports net loss of $1.7 million for second quarter 2014

GenVec reports net loss of $1.7 million for second quarter 2014

GenVec, Inc. today reported financial results for the three-month and six-month periods ended June 30, 2014. For the three-month period ended June 30, 2014, the company reported a net loss of $1.7 million or $0.10 per share on revenues of $0.1 million as compared to a net loss of $3.1 million or $0.24 per share on revenues of $0.7 million in the same period in the prior year. [More]
Plan International outlines strategies to combat Ebola outbreak

Plan International outlines strategies to combat Ebola outbreak

The current Ebola outbreak, the most severe and complex in history, is now making its impact felt worldwide. [More]
Leidos funds National Veterans Wheelchair Games to be held in Philadelphia

Leidos funds National Veterans Wheelchair Games to be held in Philadelphia

Leidos, a national security, health and engineering solutions company, is a Platinum Sponsor of the 34th National Veterans Wheelchair Games scheduled for Aug. 12-17 in Philadelphia, Pa. [More]
Injecting vaccine-like compound into mice effective in protecting from malaria

Injecting vaccine-like compound into mice effective in protecting from malaria

A study led by Johns Hopkins Bloomberg School of Public Health researchers found that injecting a vaccine-like compound into mice was effective in protecting them from malaria. [More]
New approach to knocking out parasite's genes

New approach to knocking out parasite's genes

Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists' efforts to study its genetics. [More]
Antimalarial agent chloroquine normalizes abnormal tumor blood vessels

Antimalarial agent chloroquine normalizes abnormal tumor blood vessels

A recent study by investigators at VIB and KU Leuven has demonstrated that chloroquine also normalizes the abnormal blood vessels in tumors. This blood vessel normalization results in an increased barrier function on the one hand -- thereby blocking cancer cell dissemination and metastasis -- and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy. [More]
Combination therapy effective in treating drug-resistant malaria

Combination therapy effective in treating drug-resistant malaria

Resistance to artemisinin, the main drug to treat malaria, is now widespread throughout Southeast Asia, among the Plasmodium falciparum (P. falciparum) parasites that cause the disease and is likely caused by a genetic mutation in the parasites. [More]

Researchers discover new vaccine targets to combat malaria

Researchers have discovered new vaccine targets that could help in the battle against malaria. Taking a new, large-scale approach to this search, researchers tested a library of proteins from the Plasmodium falciparum parasite with antibodies produced by the immune systems of a group of infected children. [More]

Cloud Pharmaceuticals awarded Phase I grant from NSF SBIR program

Cloud Pharmaceuticals, Inc., a therapeutics company focused on cloud-based drug design and development, announced today that it has been awarded a Phase I grant from the National Science Foundation Small Business Innovation Research program. [More]
Researchers uncover how malaria parasite becomes resistant to fosmidomycin drug

Researchers uncover how malaria parasite becomes resistant to fosmidomycin drug

Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery, at Washington University School of Medicine in St. Louis, also is relevant for other infectious diseases including bacterial infections and tuberculosis. [More]
New momentum: WHO welcomes progress in tackling viral hepatitis

New momentum: WHO welcomes progress in tackling viral hepatitis

On World Hepatitis Day, 28 July, WHO welcomes new progress in tackling one of the world's most serious diseases. Viral hepatitis - a group of infectious diseases known as hepatitis A, B, C, D, and E - affects millions of people worldwide, causing acute and chronic liver disease and killing close to 1.4 million people every year. [More]
Researchers prove that CD27 drug is true alternative against malaria

Researchers prove that CD27 drug is true alternative against malaria

Researchers from the Universitat Politècnica de Catalunya · BarcelonaTech (UPC), the Instituto de Química Mèdica (IQM-CSIC) and the University of Glasgow have proved that the CD27 drug is a true alternative against malaria. [More]