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Malaria is a mosquito-borne disease caused by a parasite called Plasmodium - when infected mosquitoes bite the human body, the parasites multiply in the liver, and then infect red blood cells. Even though this potentially fatal disease can be prevented and cured, each year 350-500 million cases of malaria still occur worldwide, and over one million people die, most of them young children in Africa south of the Sahara, where one in every five (20%) childhood deaths is due to the effects of the disease.

Malaria is so common in Africa because a lack of resources and political instability have prevented the building of solid malaria control programs. Experts say an African child has on average between 1.6 and 5.4 episodes of malaria fever each year and according to the World Health Organization (WHO) as many as half of the world's population are at risk of malaria mainly in the world's poorest and most vulnerable countries and every 30 seconds a child dies from malaria.
Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers have been named winners of the 2016 Elsevier Foundation Awards for Early Career Women Scientists in the Developing World, in recognition of research that has strong potential health and economic benefits. [More]
Gut microbes influence severity of malaria

Gut microbes influence severity of malaria

Microorganisms in the gut could play a role in reducing the severity of malaria, according to a new study co-authored by researchers at the University of Tennessee, Knoxville, and the University of Louisville. [More]
Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia. [More]
Discovery may help researchers identify new ways to attack malaria parasite

Discovery may help researchers identify new ways to attack malaria parasite

New anti-malarial drugs could be developed after researchers discovered a new mechanism used by the malaria parasite when it infects humans. [More]
Falls in stillbirth rates failing to keep pace with childhood, maternal mortality rates

Falls in stillbirth rates failing to keep pace with childhood, maternal mortality rates

Approximately 2.6 million babies were stillborn in 2015, or around 7200 every day globally. Falls in stillbirth rates since the year 2000 are failing to keep pace with falls in childhood and maternal mortality rates, say the authors of The Lancet’s new Ending preventable stillbirths Series. [More]
New technique may accelerate development of novel vaccines

New technique may accelerate development of novel vaccines

An interdisciplinary team of Oxford University researchers has devised a new technique to speed up the development of novel vaccines. [More]
Study shows slow global progress on stillbirth prevention leaves over 2.6 million babies at risk each year

Study shows slow global progress on stillbirth prevention leaves over 2.6 million babies at risk each year

More than 2.6 million stillbirths continue to occur globally every year with very slow progress made to tackle this 'silent problem', according to new research published in The Lancet. Despite significant reductions in the number of maternal and child deaths, there has been little change in the number of stillbirths (in the third trimester of pregnancy) even though the majority are preventable. [More]
Study may hold new revelations about how stress during pregnancy affects mothers and offspring

Study may hold new revelations about how stress during pregnancy affects mothers and offspring

The sequencing of the first genome involving a cockroach species may one day serve as a model system comparable to how research on mice can apply to humans. In this case, the model could hold new revelations about how stress during pregnancy could affect both the mother and her offspring. [More]
Study reveals promising mechanism for attacking Ebola virus

Study reveals promising mechanism for attacking Ebola virus

In late December, nearly two years after the epidemic began, the World Health Organization has declared the African country of Guinea to be free of Ebola virus infections. But, the race to find a cure and therapies to combat the disease are forging ahead as officials warn that inattention could lead to another epidemic. [More]
Study shows why immune system fails to develop immunity during malaria infection

Study shows why immune system fails to develop immunity during malaria infection

Australian scientists have for the first time revealed how malaria parasites cause an inflammatory reaction that sabotages our body's ability to protect itself against the disease. [More]
Researchers identify 124 protein targets of artemisinin in most pathogenic malaria parasite

Researchers identify 124 protein targets of artemisinin in most pathogenic malaria parasite

A team of researchers from the National University of Singapore (NUS) has uncovered the mystery behind the potent parasite-killing effect of artemisinin, a drug that is considered to be the last line of defence against malaria. Given the emergence of artemisinin resistance, these findings could potentially lead to the design of new treatments against drug-resistant parasites. [More]
NUS scientists uncover mystery behind potent parasite-killing effect of artemisinin

NUS scientists uncover mystery behind potent parasite-killing effect of artemisinin

A team of researchers from the National University of Singapore has uncovered the mystery behind the potent parasite-killing effect of artemisinin, a drug that is considered to be the last line of defence against malaria. Given the emergence of artemisinin resistance, these findings could potentially lead to the design of new treatments against drug-resistant parasites. [More]
Turing Pharmaceuticals emphasizes continued availability of Daraprim

Turing Pharmaceuticals emphasizes continued availability of Daraprim

Turing Pharmaceuticals AG, a privately-held biopharmaceutical company focused on developing and commercializing innovative treatments for serious diseases and conditions, today emphasizes the continued availability of Daraprim and cautions healthcare providers of proposed alternatives to Daraprim. [More]
New funding supports research on new and improved drug treatments for tuberculosis, malaria

New funding supports research on new and improved drug treatments for tuberculosis, malaria

University of Toronto and McGill University scientists are leading an international partnership to discover new and improved drug treatments for tuberculosis, malaria and neglected tropical diseases -- thanks to a contribution from Merck Canada Inc., as well as an additional $5 million supplement to a grant from the Bill & Melinda Gates Foundation. [More]
Revolutionary new app can capture accurate global cause of death data

Revolutionary new app can capture accurate global cause of death data

Researchers have developed a revolutionary new app to capture accurate global cause of death data on tablets and mobile phones. [More]
Global Health Impact Index can measure actual impact of drugs worldwide

Global Health Impact Index can measure actual impact of drugs worldwide

Billions of dollars have been spent on developing drugs and supplying them around the world, but which companies' drugs are actually making an impact? The Global Health Impact Index, headed by Binghamton University Associate Professor Nicole Hassoun and highlighted in a new article published Friday in PLOS ONE, addresses this issue by ranking pharmaceutical companies based on their drugs' impact on global health. [More]
New rapid test can detect malaria parasites, viruses and biomarkers

New rapid test can detect malaria parasites, viruses and biomarkers

Nothing could be simpler: a drop of blood is placed on a special carrier substance; after a wait of a few minutes, the slide is placed on a device that emits polarised light thanks to an inexpensive polarisation filter. It is covered with a lid containing a second polarisation filter, which blocks the light from all materials except crystalline or materials with directional properties. [More]
Penn State researchers receive $10.2 million grant to investigate new method for preventing malaria

Penn State researchers receive $10.2 million grant to investigate new method for preventing malaria

In collaboration with partners in Europe and Africa, researchers at Penn State have received a five-year, $10.2-million grant from the Bill & Melinda Gates Foundation to investigate a new method for preventing the transmission of malaria. [More]
Early life exposures to toxic chemicals reduce infants' response to TB vaccine

Early life exposures to toxic chemicals reduce infants' response to TB vaccine

Early life exposures to toxic chemicals such as PCBs and DDT dampen an infant's response to the tuberculosis vaccine, according to a new study from the University of Rochester Environmental Health Sciences Center. [More]
TB sidetracked in the fight against HIV epidemic in Malawi

TB sidetracked in the fight against HIV epidemic in Malawi

Tuberculosis seems to have fallen between the cracks in poverty-stricken Malawi's sponsor-dependent health sector. The dominating focus on HIV may have left parts of Africa with a skewed health service, say researchers. [More]
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