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Findings reveal a new way to prevent meningitis

Findings reveal a new way to prevent meningitis

The fungus Cryptococcus causes meningitis, a brain disease that kills about 1 million people each year — mainly those with impaired immune systems due to AIDS, cancer treatment or an organ transplant. [More]
Researchers find fatty acid deposits in brains of Alzheimer's patients

Researchers find fatty acid deposits in brains of Alzheimer's patients

People with Alzheimer's disease have fat deposits in the brain. For the first time since the disease was described 109 years ago, researchers affiliated with the University of Montreal Hospital Research Centre (CRCHUM) have discovered accumulations of fat droplets in the brain of patients who died from the disease and have identified the nature of the fat. [More]
New ORNL interface can identify, characterize solid or liquid sample

New ORNL interface can identify, characterize solid or liquid sample

In mere seconds, a system developed at the Department of Energy's Oak Ridge National Laboratory can identify and characterize a solid or liquid sample, providing a valuable tool with applications in material science, forensics, pharmaceuticals, biology and chemistry. [More]
Better drug design may soon be aided by Scripps scientists’ discoveries

Better drug design may soon be aided by Scripps scientists’ discoveries

For the first time, they have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output. These new findings could aid future drug design by giving scientists an edge in fine tuning the signal between these partnered proteins—and the drug’s course of action. [More]
New TSRI study may have important implications for better drug design

New TSRI study may have important implications for better drug design

Scientists from The Scripps Research Institute Florida campus have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output. These new findings could aid future drug design by giving scientists an edge in fine tuning the signal between these partnered proteins—and the drug's course of action. [More]
Agena Bioscience releases Chip prep module to automate sample handling after PCR for MassARRAY System

Agena Bioscience releases Chip prep module to automate sample handling after PCR for MassARRAY System

Agena Bioscience today introduced the Chip prep module to automate sample handling after PCR for the MassARRAY 96-well System. This enables laboratories to operate the MassARRAY System largely unattended for high-throughput, multiplex genetic analysis. [More]
caprotec bioanalytics issued U.S. patent for CCMS proteome analysis technology

caprotec bioanalytics issued U.S. patent for CCMS proteome analysis technology

caprotec bioanalytics GmbH announced today that the United States Patent Office has issued patent No. US9,034,789 covering its revolutionary Capture Compound Mass Spectrometry (CCMS) technology. [More]
Synthorx employs synthetic DNA technology to produce proteins containing novel amino acids

Synthorx employs synthetic DNA technology to produce proteins containing novel amino acids

Synthorx Inc. announced today that the company has employed its proprietary protein expression system to successfully produce proteins containing novel amino acids. Using a semi-synthetic DNA template (containing the synthetic base pair X and Y), Synthorx scientists were able to produce RNA containing X and Y, which was used with an otherwise fully natural biological system, to efficiently direct the incorporation of multiple novel amino acids at different sites in proteins. [More]
New endoscopic system differentiates between malignant and benign tumors in gastrointestinal tract

New endoscopic system differentiates between malignant and benign tumors in gastrointestinal tract

Cancer or no cancer? This question can usually only be answered after a days-long wait for a histological examination. With the use of a mass spectrometric technique, the answer may soon be available in real time. [More]
Study determines structure of plant hormone that helps regulate plants’ responses to insects, microorganisms

Study determines structure of plant hormone that helps regulate plants’ responses to insects, microorganisms

An international collaboration including scientists from the Florida campus of The Scripps Research Institute has determined the structure of a plant hormone that plays a crucial role in regulating plants’ responses to insects and disease-causing microorganisms as well as normal growth and development. [More]
Scientists develop technique to identify Viagra and other hidden ingredients in dietary supplements

Scientists develop technique to identify Viagra and other hidden ingredients in dietary supplements

To lose weight, boost energy or soothe nerves, many consumers turn to dietary supplements. But some of these products contain undeclared substances. To protect consumers from taking something without their knowledge, scientists have developed a technique to determine what secret ingredients could be lurking in these supplements. [More]
New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

The importance of a diet rich in fish oils - now a billion dollar food-supplement industry -- has been debated for over half a century. A few large clinical trials have supported the idea that fish oils confer therapeutic benefits to patients with cardiovascular disease. Researchers think that hearts and blood vessels may benefit in part from their anti-inflammatory properties. [More]

Using physical processes to treat ships' ballast water can prevent spread of harmful organisms into local environment

Untreated ballast water discharge from ships can spread living organisms and even pathogens across the world thereby introducing non-native or invasive species into the local environment. Scientists at Helmholtz Zentrum München therefore recommend using physical treatment processes such as filtration rather than electrochemical disinfection, which creates countless potentially toxic compounds. [More]
WSU scientists suggest that glyphosate not present in human breast milk

WSU scientists suggest that glyphosate not present in human breast milk

Washington State University scientists have found that glyphosate, the main ingredient in the herbicide Roundup, does not accumulate in mother's breast milk. [More]
Experts to highlight new diagnostic products, tools to identify heart attacks at 2015 AACC Annual Meeting

Experts to highlight new diagnostic products, tools to identify heart attacks at 2015 AACC Annual Meeting

The 2015 AACC Annual Meeting & Clinical Lab Expo, the leading annual event for laboratory medicine, will open on Sunday, July 26, in Atlanta, Georgia. This year's meeting will host more than 400 educational sessions on topics ranging from personalized medicine and infectious diseases to point-of-care and laboratory-developed tests, and will feature more than 200 new cutting edge diagnostic products. [More]
Study points to potential treatment for thrombotic thrombocytopenic purpura

Study points to potential treatment for thrombotic thrombocytopenic purpura

A rare autoimmune disease creates sudden pain in the abdomen or the head, sending a patient to the emergency room with a potentially fatal condition. The pain comes from a multitude of blockages of tiny blood vessels, formed after the patient's own immune system somehow inhibits an enzyme that is vital to control clotting. [More]
C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

C2N Diagnostics and AbbVie today announced that the U.S. Food and Drug Administration has granted their investigational recombinant humanized anti-tau antibody, C2N-8E12 (ABBV-8E12), an orphan drug designation for the treatment of progressive supranuclear palsy (PSP). [More]
Scientists gain insights into dynamic remodeling of tissue during lung repair

Scientists gain insights into dynamic remodeling of tissue during lung repair

Our lungs are permanently exposed to harmful environmental factors that can damage or even destroy their cells. In a specific regenerative process these injured cells must be replaced as soon as possible. In collaboration with colleagues from the Max Planck Institute of Biochemistry, scientists at the Helmholtz Zentrum München have now, for the first time, gained detailed insights into the dynamic remodeling of the tissue during lung repair. [More]
Transitioning infrared imaging into clinical use: an interview with Dr Matthew Baker

Transitioning infrared imaging into clinical use: an interview with Dr Matthew Baker

The CLIRSPEC network is a UK Engineering and Physical Sciences Research Council (EPSRC – EP/L012952/1) funded network in clinical infrared and Raman spectroscopy. Infrared and Raman spectroscopy can identify the hallmarks of disease and distinguish between diseased and non-diseased samples based upon inherent chemistry. [More]
Histones steadily replaced in brain cells throughout life, find Mount Sinai researchers

Histones steadily replaced in brain cells throughout life, find Mount Sinai researchers

For decades, researchers in the genetics field have theorized that the protein spools around which DNA is wound, histones, remain constant in the brain, never changing after development in the womb. [More]
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