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Study: Iodine deficiency during pregnancy can impair child's intellectual development

Study: Iodine deficiency during pregnancy can impair child's intellectual development

Pregnant women in Austria commonly suffer from an iodine deficiency. This may have a negative impact on the development of their unborn child's brain. These are the key findings of a joint study by the Endocrinology and Metabolism Unit at the University Department of Internal Medicine III together with the University Department of Gynaecology at the MedUni Vienna and AGES, which have now been published in the European Journal of Clinical Nutrition. [More]
Study leads to discovery of rare genetic disorder

Study leads to discovery of rare genetic disorder

Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding the effects of this mutation, research by scientists at the RIKEN-Max Planck Joint Research Center in Japan implicates the enzyme ENGase as the factor responsible for deficient protein degradation that occurs in the absence of mouse Ngly1 gene expression. [More]
Iron accumulation in human tissues may contribute to the aging process

Iron accumulation in human tissues may contribute to the aging process

It's been known for decades that some metals, including iron, accumulate in human tissues during aging and that toxic levels of iron have been linked to neurologic diseases, such as Parkinson's. Common belief has held that iron accumulation happens as a result of the aging process. [More]
CNIO researchers identify new mechanism that influences differentiation of keratinocytes

CNIO researchers identify new mechanism that influences differentiation of keratinocytes

The formation of human skin involves a cascade of biochemical signals, which are not well understood. However, they are very important since their failure may cause diseases, such as Atopic Dermatitis and skin cancers, which affect more than 25% of the human population. [More]
Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Researchers at Columbia University Medical Center have found that, in addition to gluten, the immune systems of patients with celiac disease react to specific types of non-gluten protein in wheat. The results were reported online in the Journal of Proteome Research. [More]
Researchers develop new method to track movement of carcinogenic PAHs in the human body

Researchers develop new method to track movement of carcinogenic PAHs in the human body

Researchers for the first time have developed a method to track through the human body the movement of polycyclic aromatic hydrocarbons, or PAHs, as extraordinarily tiny amounts of these potential carcinogens are biologically processed and eliminated. [More]
Real-time surgical guidance study to evaluate TriVersa NanoMate with LESA capability from Advion

Real-time surgical guidance study to evaluate TriVersa NanoMate with LESA capability from Advion

Advion, Inc. announces that is its TriVersa NanoMate with liquid extraction surface analysis (LESA) capability will be evaluated as part of a study at Brigham and Women’s Hospital. [More]
Antibiotic for infections comes from good bacteria found in turkeys

Antibiotic for infections comes from good bacteria found in turkeys

While the turkey you eat on Thursday will bring your stomach happiness and could probably kick-start an afternoon nap, it may also save your life one day. [More]
Quadrupole time-of-flight mass spectrometry for life science research analysis announced by Bruker

Quadrupole time-of-flight mass spectrometry for life science research analysis announced by Bruker

Bruker Corporation (NASDAQ: BRKR) announced today, the evolution of their maXis™ line of ultrahigh-resolution quadrupole time-of-flight (UHR-qTOF) mass spectrometers, bringing industry-leading resolution and mass accuracy to the liquid chromatography, time-of-flight MS market space. [More]
AB SCIEX introduces DiscoveryQuant 3.0 Software for high throughput pharmaceutical laboratories

AB SCIEX introduces DiscoveryQuant 3.0 Software for high throughput pharmaceutical laboratories

AB SCIEX, a global leader in life science analytical technologies, today introduced DiscoveryQuant 3.0 Software, a new version of its proven ADME software that enables scientists to significantly reduce LC/MS method development and optimization time for high throughput drug discovery (ADME) laboratories focusing on both small molecules and biotherapeutics. [More]
Scientists identify potent inhibitors to combat common obesity gene

Scientists identify potent inhibitors to combat common obesity gene

Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene. [More]
Identifying infections rapidly: an interview with Dr. David J. Ecker

Identifying infections rapidly: an interview with Dr. David J. Ecker

Current methods for diagnosing infectious diseases are based on the 150-year-old culture method, where physicians collect a sample of a patient’s tissue, such as blood, mucus or urine, and transfer it onto media bottle to allow the pathogens to grow. [More]
Proteins linked to severe forms of ALS are less stable, suggests new study

Proteins linked to severe forms of ALS are less stable, suggests new study

A new study by scientists from The Scripps Research Institute, Lawrence Berkeley National Laboratory and other institutions suggests a cause of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. [More]
BIDMC scientists uncover new class of molecules that protects against diabetes

BIDMC scientists uncover new class of molecules that protects against diabetes

Scientists at the Salk Institute and Beth Israel Deaconess Medical Center in Boston have discovered a new class of molecules—produced in human and mouse fat—that protects against diabetes. [More]
Slug flow microextraction method for drug testing yields results in one minute

Slug flow microextraction method for drug testing yields results in one minute

A new technique makes it possible to quickly detect the presence of drugs or to monitor certain medical conditions using only a single drop of blood or urine, representing a potential tool for clinicians and law enforcement. [More]
Discovery offers promising new avenue for prevention, treatment of type 2 diabetes

Discovery offers promising new avenue for prevention, treatment of type 2 diabetes

The surprising discovery of a previously unidentified class of lipid molecules that enhance insulin sensitivity and blood sugar control offers a promising new avenue for the prevention and treatment of type 2 diabetes. [More]
AB SCIEX announces R&D Director has been awarded the HUPO Science and Technology Award

AB SCIEX announces R&D Director has been awarded the HUPO Science and Technology Award

AB SCIEX, a global leader in life science analytical technologies, announced that Dr. Subhasish “Babu” Purkayastha, Director, R&D at AB SCIEX, has been awarded the Human Proteome Organization (HUPO) Science and Technology Award for efforts in commercialization of isobaric labeling for protein quantification with the development of iTRAQ chemistries. [More]
Exclusive partnership brings together next-generation proteomics and next-generation sequencing

Exclusive partnership brings together next-generation proteomics and next-generation sequencing

AB SCIEX and Illumina (NASDAQ: ILMN) announced today the OneOmics™ project, an exclusive partnership to bring together SWATH™-based next-generation proteomics (NGP) and next-generation sequencing (NGS) tools in a cloud computing environment. [More]
Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Imperial chemists have gained fresh insights into how a disease-causing enzyme makes changes to proteins and how it can be stopped. [More]
Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

With a new $5.8 million, three-year award from the National Institutes of Health, researchers at the University of Pittsburgh School of Medicine will further develop a state-of-the-art, microfluidic 3D model system that mimics structure and function of the liver to better predict organ physiology, assess drug toxicity and build disease models. [More]