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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.
Scientists undertake major biomedical research initiative to escalate problem of sepsis

Scientists undertake major biomedical research initiative to escalate problem of sepsis

A multidisciplinary team of scientists -- including two UC Santa Barbara faculty members -- is poised to undertake a major biomedical research initiative focused on the escalating problem of sepsis, the body's abnormal response to severe infections. [More]
New mass spectrometry imaging protocol allows analysis of metabolite composition of tissues

New mass spectrometry imaging protocol allows analysis of metabolite composition of tissues

In biomedical research, working with tissue samples is indispensable because it permits insights into the biological reality of patients, for example, in addition to those gained from Petri dishes and computer simulations. [More]
CDC invests in Donator’s unique heat stabilization technology

CDC invests in Donator’s unique heat stabilization technology

Denator, the Swedish-based biotechnology company specialized in biological sample preparation technologies announced today that the Center for Disease Control and Prevention, Atlanta, had made a major purchase of its proprietary heat stabilization technology Stabilizor T1™. [More]

Laser-printed micropatterns can serve as platform for diagnostic applications

Laser printouts on paper might be used as a platform for low-cost organic electronics, microfluidic, or sensor applications. German scientists at Humboldt University Berlin have now developed a procedure for the selective coating of laser-printed micropatterns on paper. [More]
Study focuses on critical proteins involved in ovarian cancer biology

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors. [More]
Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

For a promising pathway to treating Alzheimer's patients, "aim here." That's what National Institute of Standards of Technology researchers advised collaborators hunting for molecules that, by linking to a normally occurring enzyme, rev up the brain's capacity for clearing cholesterol--a boost associated with improvements in memory and other benefits in animal studies. [More]
Non-invasive fluid-based biomarker could help identify aggressive prostate cancer before surgery

Non-invasive fluid-based biomarker could help identify aggressive prostate cancer before surgery

Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery. [More]
The scent dogs smell on diabetics’ breath could offer key to new tests

The scent dogs smell on diabetics’ breath could offer key to new tests

An increase in the level of the chemical isoprene may be the warning sign some dogs can detect in the breath of patients with type 1 diabetes who are reaching risky low levels of blood sugar, according to research by the University of Cambridge. [More]
New analytical technology could improve cancer treatment by establishing ideal dosing regimens

New analytical technology could improve cancer treatment by establishing ideal dosing regimens

University of Oklahoma researchers will apply a new analytical technology that could ultimately provide a powerful tool for improved treatment of cancer patients in Oklahoma and beyond. Using mass spectrometry, an analytical instrument for sensitive detection and accurate [More]
Scientists develop new tool to overcome major hurdle for personalized medicine

Scientists develop new tool to overcome major hurdle for personalized medicine

Scientists from EPFL and ETHZ have developed a powerful tool for exploring and determining the inherent biological differences between individuals, which overcomes a major hurdle for personalized medicine. [More]
Postnova reports advances in analysis of plasma proteins using AF4-ICP-MS system

Postnova reports advances in analysis of plasma proteins using AF4-ICP-MS system

Postnova Analytics reports on exciting advances in the analysis of plasma proteins using a hyphenated system that couples asymmetric flow Field-Flow Fractionation (AF4) and inductively coupled plasma-mass spectrometry. [More]
New method helps speed up bacterial identification

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge. [More]
Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome. [More]
NMR-based metabolomics: an interview with Prof. Claudio Luchinat

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

We started from theoretical inorganic to bioinorganic chemistry, so looking at metals in proteins, enzymes and so on. About 30% of all the proteins that we have are metalloproteins, so it’s a huge contribution that inorganic chemistry is providing for life. [More]

RapifleX MALDI PharmaPlus Solution for uHTS launched by Bruker

At the 64th ASMS Conference, Bruker announces the launch of the new rapifleX™ MALDI PharmaPulse™ (MPP) solution. It is the latest addition to Bruker’s portfolio of innovative products designed to assist pharmaceutical, biotech and CRO customers to accelerate drug discovery, and rapifleX MPP can dramatically lower the cost of ultra-high throughput screening (uHTS) with further improved results. [More]
Innovative RapifleX MALDI-TOF/TOF showcased by Bruker

Innovative RapifleX MALDI-TOF/TOF showcased by Bruker

At the 64th ASMS Conference, Bruker introducesrapifleX™, the highest performance MALDI-TOF/TOF mass spectrometer, which had been shown as work-in-progress to early adopters at HUPO 2015. [More]
Introducing the innovative timsTOF mass spectrometer

Introducing the innovative timsTOF mass spectrometer

At the 64th ASMS Conference, Bruker introduces an entirely new mass spectrometry technology platform: the innovative timsTOF™ system combines very high ion mobility resolution greater than 200, using Bruker’s proprietary Trapped Ion Mobility Spectrometry (TIMS), with Bruker’s ultra-high performance ESI-QTOF mass spectrometry. [More]
More effective absorption with a pioneering oral vitamin spray

More effective absorption with a pioneering oral vitamin spray

What a difference a spray makes when it comes to effectively absorbing key nutrients, say health pioneers BetterYou following the BBC’s 'The Truth About Healthy Eating' programme which aired last week (2 June). [More]
Analysing blood metabolites may help monitor effects of novel drugs

Analysing blood metabolites may help monitor effects of novel drugs

Testing for metabolic changes in the blood could indicate whether a cancer drug is working as designed, a new study reports. [More]
Using proteomic mass spectrometry imaging to detect malignant melanoma: an interview with Stephen Turner

Using proteomic mass spectrometry imaging to detect malignant melanoma: an interview with Stephen Turner

Today, using anatomic pathology, the differences in appearance of a normal or a malignant lesion can be difficult to tell when just using light microscopy. [More]
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