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Using 'click chemistry' to create novel multi-protein anti-cancer agents

A potent anti-cancer therapy has been created using Nobel prize-winning "click chemistry", where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.

24 Jul 2023

Novel geometric deep learning model improves stroke lesion segmentation

Ischemic stroke, which occurs when a blood vessel in the brain gets blocked by a clot, is among the leading causes of death worldwide.

18 Jul 2023

Predicting kidney abnormalities in utero with deep learning

Researchers examine the potential use of deep learning models to diagnose fetal kidney anomalies.

17 Jul 2023

Synoptic reports improve completeness of pretreatment CT reports in advanced ovarian cancer

According to an accepted manuscript published in the American Journal of Roentgenology (AJR), a synoptic report improved completeness of pretreatment CT reports in patients with advanced ovarian cancer, including for established sites of unresectable or challenging-to-resect disease.

13 Jul 2023

MRI may be more effective than CT with CTA in patients with dizziness

According to an accepted manuscript published in the American Journal of Roentgenology (AJR), patients discharged from the emergency department (ED) after CT with CTA alone could have benefitted from an alternative or additional MRI evaluation, including using a specialized abbreviated protocol for the modality.

7 Jul 2023

Using AI might afford large-scale evaluation for splenomegaly on CT examinations

According to an accepted manuscript published in ARRS' own American Journal of Roentgenology (AJR), using an automated deep-learning AI tool, as well as weight-based volumetric thresholds, might afford large-scale evaluation for splenomegaly on CT examinations performed for any indication.

3 Jul 2023

Deep learning model could help identify high-risk patients with community-acquired pneumonia

According to an accepted manuscript published in ARRS' own American Journal of Roentgenology (AJR), a deep learning-based model using initial chest radiographs predicted 30-day mortality in patients with community-acquired pneumonia (CAP), improving upon the performance of an established risk prediction tool (i.e., CURB-65 score).

30 Jun 2023

Transient ischemic attack with incomplete neurovascular imaging linked to higher risk of subsequent stroke

According to an accepted manuscript published in ARRS' own American Journal of Roentgenology (AJR), transient ischemic attack (TIA) emergency department (ED) encounters with incomplete neurovascular imaging were associated with higher odds of subsequent stroke within 90 days.

8 Jun 2023

Deep learning–based computer-aided diagnosis for breast lesion classification

According to an accepted manuscript published in ARRS' own American Journal of Roentgenology (AJR), deep learning–based computer-aided diagnosis (CAD) for breast lesion classification on ultrasound significantly improved radiologists' diagnostic performance-;particularly for reducing the frequency of benign breast biopsies.

25 May 2023

Dynamic Coronary Roadmap effectively reduces iodinated contrast during PCI

Results from Dynamic Coronary Roadmap for Contrast Reduction (DCR4Contrast), a multi-center prospective, unblinded, randomized controlled trial were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions.

18 May 2023

Myosteatosis linked to increased risk of major adverse events and death

Asymptomatic adults with a high accumulation of fat in their muscles, known as myosteatosis, are at an increased risk of major adverse events and death, according to a study published in Radiology, a journal of the Radiological Society of North America.

16 May 2023

MGI Empowers the Completion of Nearly 60,000 Samples for The Million Microbiome of Humans Project

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From MGI 10 May 2023

UVA researcher receives Trailblazer R21 Award to improve cardiac resynchronization therapy outcomes

Pacemakers and other implantable devices that restore normal heart rhythms have saved millions of lives.

8 May 2023

The African Personalized Medicine Agenda

In this interview, Rizwana Mia, the Senior Program Manager at South African Medical Research Council, talks to News Medical about the African personalized medicine agenda.

From MGI 4 May 2023

How the COVID pandemic has improved genomics

In this interview, Davide Cacchiarelli, Molecular Biology and Genomics Professor at the University of Naples talks to NewsMed about how the COVID pandemic has highlighted the vital role of genomic surveillance and improved genomics.

From MGI 4 May 2023

The Human Protein Atlas and Precision Medicine

In this interview, Mathias Uhlen, the Director of the Human Protein Atlas, talks to NewsMed about the Human Protein Atlas and Precision Medicine.

From MGI 4 May 2023

AI tool can predict the chance of cardiac events

What if your physician could predict if-;or when-;you might experience a heart attack, cardiac arrest or another heart-related problem?

2 May 2023

Researchers shed light on the genetics behind facial changes in Down syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

26 Apr 2023

ChatGPT-4 outperforms GPT-3.5 and Google Bard in neurosurgery oral board exam

Researchers evaluate the performance of three large language models (LLMs) on a question bank designed for neurosurgery oral board examination preparation. The study found that GPT-4 achieved the highest score of 82.6%, outperforming ChatGPT and Google's Bard.

19 Apr 2023

New deep learning-based model estimates breast density with high precision

Breast cancer is the most common cancer to affect women worldwide. According to the American Cancer Society, about 1 in 8 women in the United States will develop breast cancer in their lifetime.

7 Apr 2023