Melanomas News and Research RSS Feed - Melanomas News and Research

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

A team led by Fengzhi Li, PhD, and Xinjiang Wang, PhD, of Roswell Park Cancer Institute has reported new findings regarding therapeutic targets of the novel anticancer agent FL118. Previous studies from these researchers have showed that FL118 induces cancer cell death, or apoptosis, by inhibiting expression of multiple cell-survival proteins (survivin, Mcl-1, XIAP or cIAP2). [More]
Study reports anti-cancer activity in mice treated with experimental drug TAK-733

Study reports anti-cancer activity in mice treated with experimental drug TAK-733

A University of Colorado Cancer Center study published online this week in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2. [More]
UCSD researchers define epidemiology of gastrointestinal stromal tumors

UCSD researchers define epidemiology of gastrointestinal stromal tumors

Researchers at the University of California, San Diego School of Medicine have, for the first time, clearly defined the epidemiology of gastrointestinal stromal tumors (GIST), which occur primarily in the lining of the stomach and small intestine. [More]
Gigapixel whole-body photographic camera may help doctors spot cancer early, save lives

Gigapixel whole-body photographic camera may help doctors spot cancer early, save lives

Melanoma is the fifth most common cancer type in the United States, and it's also the deadliest form of skin cancer, causing more than 75 percent of skin-cancer deaths. If caught early enough though, it is almost always curable. Now a camera, capable of taking snapshots of the entire human body and rendering high-resolution images of a patient's skin may help doctors spot cancer early and save lives. [More]
Longer telomeres increase melanoma risk

Longer telomeres increase melanoma risk

A leading Dartmouth researcher, working with The Melanoma Genetics Consortium, GenoMEL, an international research consortium, co-authored a paper published today in the Journal of the National Cancer Institute that proves longer telomeres increase the risk of melanoma. [More]
Penn Medicine, Wistar Institute awarded NCI grants for four new melanoma research projects

Penn Medicine, Wistar Institute awarded NCI grants for four new melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $12.1 million SPORE grant from the National Cancer Institute. The five-year Specialized Programs of Research Excellence, or SPORE, grant will fund four new melanoma research projects that aim to translate fundamental laboratory discoveries into new therapeutics to treat melanoma and other skin cancers. [More]
Study evaluates impact of myPath Melanoma diagnostic test

Study evaluates impact of myPath Melanoma diagnostic test

Myriad Genetics, Inc. today presented results from a pivotal clinical utility study of the Myriad myPath- Melanoma test at the 2014 College of American Pathologists (CAP) annual meeting in Chicago, Ill. [More]
Genetic mutation caused by ultraviolet light is likely driving force behind human skin cancers

Genetic mutation caused by ultraviolet light is likely driving force behind human skin cancers

A genetic mutation caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to researchers at the Stanford University School of Medicine. [More]
Ascend Biopharmaceuticals provides update on clinical trial program for lead immunotherapy products

Ascend Biopharmaceuticals provides update on clinical trial program for lead immunotherapy products

Ascend Biopharmaceuticals, a Melbourne-based immunotherapy company, has released an update on the clinical trial pipeline for its lead immunotherapy products treating basal cell carcinoma (BCC) and breast cancer. [More]
Scientists study about rare type of skin cancer, acral melanomas

Scientists study about rare type of skin cancer, acral melanomas

Acral melanomas, the rare type of skin cancer that caused musician Bob Marley's death, are genetically distinct from other types of skin cancer. [More]
Anti-EphA3 antibody has anti-tumour effects against solid cancers

Anti-EphA3 antibody has anti-tumour effects against solid cancers

An international team of scientists has shown that an antibody against the protein EphA3, found in the micro-environment of solid cancers, has anti-tumour effects. [More]
Genetic testing in melanoma: an interview with Dr. Diane McDowell, US Medical Affairs Lead, Oncology, GSK

Genetic testing in melanoma: an interview with Dr. Diane McDowell, US Medical Affairs Lead, Oncology, GSK

Genetic testing, the commonly used process of looking for changes in a person's genes or chromosomes that may be associated with specific diseases or conditions, dates back to before President Richard Nixon declared the War on Cancer with the passage of the National Cancer Act in 1971. [More]
Melanoma in adulthood can be reduced by consistent use of sunscreen in childhood

Melanoma in adulthood can be reduced by consistent use of sunscreen in childhood

Research conducted at the Texas Biomedical Research Institute, published in the latest issue of the scientific journal Pigment Cell and Melanoma, has established unequivocally in a natural animal model that the incidence of malignant melanoma in adulthood can be dramatically reduced by the consistent use of sunscreen in infancy and childhood. [More]
New vaccine reprograms pancreatic tumors and makes them vulnerable to immunotherapy

New vaccine reprograms pancreatic tumors and makes them vulnerable to immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center have developed and tested a vaccine that triggered the growth of immune cell nodules within pancreatic tumors, essentially reprogramming these intractable cancers and potentially making them vulnerable to immune-based therapies. [More]
Study suggests new targets for treating rare genetic disorder and cancer

Study suggests new targets for treating rare genetic disorder and cancer

The combined action of two enzymes, Srs2 and Exo1, prevents and repairs common genetic mutations in growing yeast cells, according to a new study led by scientists at NYU Langone Medical Center. [More]
Pivotal clinical validation study of Myriad myPath Melanoma test presented at ASCO 2014

Pivotal clinical validation study of Myriad myPath Melanoma test presented at ASCO 2014

Myriad Genetics, Inc. today presented results from a pivotal clinical validation study of the Myriad myPath- Melanoma test at the 2014 American Society of Clinical Oncology annual meeting in Chicago, Ill. [More]
Rare type of melanoma that attacks palms, soles twice likely to recur, says NYU study

Rare type of melanoma that attacks palms, soles twice likely to recur, says NYU study

A rare type of melanoma that disproportionately attacks the palms and soles and under the nails of Asians, African-Americans, and Hispanics, who all generally have darker skins, and is not caused by sun exposure, is almost twice as likely to recur than other similar types of skin cancer, according to results of a study in 244 patients. [More]
Substance from pine bark is a potential source for treating melanoma

Substance from pine bark is a potential source for treating melanoma

A substance that comes from pine bark is a potential source for a new treatment of melanoma, according to Penn State College of Medicine researchers. [More]

Cancer Council urges Queenslanders to get to know their own skin

Cancer Council is urging Queenslanders to get to know their own skin and stay vigilant about early detection, with reports of misdiagnosis for some types of melanoma in the Australasian Journal of Dermatology. [More]

ABCDE rule outlines warning signs of melanoma

It is estimated that one in five Americans will be diagnosed with skin cancer in the course of their lifetime, and one person dies from melanoma - the deadliest form of skin cancer - every hour. [More]