Metabolic Disease News and Research

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Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

An astounding 30% of Americans currently have metabolic dysfunction-associated steatotic liver disease, or MASLD, which is formerly known as nonalcoholic fatty liver disease, or NAFLD.

27 Sep 2023

The science of when you should exercise to beat obesity

A new paper in Obesity explores the diurnal relationship of obesity to MVPA – at what time does MVPA pay off the most in preventing obesity?

25 Sep 2023

How important is inflammation and body weight in the origin of depression?

A new paper in BMC Medicine examines the role of inflammation and body mass index (BMI) in the etiology of treatment-resistant depression.

18 Sep 2023

Genetics and diet shape insulin signaling in mice

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.

13 Sep 2023

Theabrownin from dark tea may have the potential to treat insulin resistance

The effects of theabrownin (TB) from dark tea treatment on insulin resistance (IR).

8 Sep 2023

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

7 Sep 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have identified a cell metabolism process found in men with diabetes and metastatic prostate cancer that could one day lead to improved testing and treatments for Black men with these diseases.

15 Aug 2023

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.

10 Aug 2023

How effective is physical activity in alleviating obesity-related inflammation in diabetes?

Scientists determine whether physical activity can be used as an effective intervention to mitigate obesity-related inflammation in diabetes.

1 Aug 2023

Children's Colorado announces launch of the Precision Medicine Institute

Children's Hospital Colorado (Children's Colorado) today announced the launch of the Precision Medicine Institute, which will allow experts to more efficiently integrate precision medicine into care provided to patients throughout the hospital.

26 Jul 2023

Researchers uncover the biology behind insulin production

The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.

25 Jul 2023

AI-powered drug discovery offers hope for cystinosis patients

Artificial intelligence is becoming increasingly important in drug discovery. Advances in the use of Big Data, learning algorithms and powerful computers have now enabled researchers at the University of Zurich (UZH) to better understand a serious metabolic disease.

14 Jul 2023

What are the effects of insect consumption on human health?

A systematic review of human studies reveals that insect proteins are as good as other protein sources in providing essential amino acids and other health benefits.

13 Jul 2023

Study shows the long-term effects of redlining on veterans' cardiovascular health

U.S. military veterans who lived in what were once known as "redlined" areas had a higher risk for heart attacks and other cardiovascular issues, according to a new study by researchers at Case Western Reserve University, University Hospitals and the Cleveland VA Medical Center.

11 Jul 2023

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known as type 2 diabetes.

22 Jun 2023

Diet alone not the sole culprit: Unraveling the complexities of metabolic disease rise in the U.S.

In a study published in the journal Pharma Nutrition, scientists have explored the long-term impact of Western diet and lifestyle factors on the risk of metabolic disease in the United States.

19 Jun 2023

BMI not a complete measure of metabolic health, research shows

Body mass index (BMI) is not a complete measure of metabolic health, and a high proportion of U.S. adults with normal BMI still have obesity, according to research being presented Friday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study showed that transplanting fetal hematopoietic stem cells exposed to vitamin D deficiency induces diabetes.

14 Jun 2023