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Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Healthy lifestyles linked to specific metabolic markers, large study finds

Researchers identify metabolomic markers linked to healthy lifestyles in a large study, showing a connection between lipid metabolism and reduced mortality risks.

18 Feb 2024

Twin study investigates the role of the microbiome as a modifier in mental disorders

Researchers examined whether the influence of gut microbiome perturbations on various biological processes, such as the dysregulation of the hypothalamic–pituitary–adrenal axis, performance of the immune system, and the production of neurotransmitters and short-chain fatty acids contributed to the manifestation and progression of mental health disorders such as anxiety, depression, and eating disorders.

15 Feb 2024

Groundbreaking model predicts heart attack risk months in advance

Study introduces a novel biomarker-based model to predict imminent myocardial infarction (IMI), identifying key proteins and metabolites that could revolutionize early detection and prevention strategies.

14 Feb 2024

Black cumin: Ancient superseed with modern health benefits

Review discusses the multifaceted role of Nigella sativa in treating cardiometabolic diseases, highlighting its bioactive components like thymoquinone, which contribute to its antioxidant, anti-inflammatory, and anti-dyslipidemic properties.

13 Feb 2024

Microgreens: Superfoods for the future, packed with nutrients and easy to grow

Review in Heliyon highlights the nutritional superiority, cultivation methods, and health benefits of microgreens, emphasizing their potential as a sustainable functional food amidst global health and environmental challenges.

12 Feb 2024

Beyond just a berry: The multifaceted health benefits of black chokeberry

Review highlights the potential of black chokeberry (Aronia melanocarpa) in disease control and prevention, focusing on its rich polyphenol content and the diverse mechanisms through which it exerts anti-disease properties on the human body.

12 Feb 2024

Blueberries boost calmness but not cognition in metabolic syndrome study

A study in the American Journal of Clinical Nutrition finds that chronic blueberry intake does not significantly improve cognitive function, alertness, or mood in adults with metabolic syndrome, despite a slight improvement in picture recognition accuracy and self-rated calmness after a high-fat, high-sugar meal.

12 Feb 2024

Machine learning decodes data variations in metabolomics

A new study shows that it is possible to use machine learning and statistics to address a problem that has long hindered the field of metabolomics: large variations in the data collected at different sites.

12 Feb 2024

Associations between ultra-processed food consumption and phthalate exposures in pregnant women

Researchers explored the relationship between consuming ultra-processed foods and urinary phthalate concentrations during pregnancy.

12 Feb 2024

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

12 Feb 2024

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

Research in The Lancet Planetary Health links prenatal phthalate exposure to increased risks of preterm birth and low birth weight, underscoring the need for regulatory oversight on chemicals used in consumer products.

11 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

New study links legume consumption to lower risk of colorectal cancer

Researchers collated and analyzed 12 studies comprising more than 17 years’ worth of case-control experiments aimed at elucidating site-specific cancer outcomes of legume consumption.

8 Feb 2024

Study finds gut health key to combating skin diseases, eyes probiotics as potential treatment

Researchers review the significant impact of gut microbiome dysbiosis on skin diseases, suggesting probiotics could offer a new treatment path.

7 Feb 2024

Gut microbiota alterations may influence immune system changes during pregnancy

During pregnancy, a woman's immune system changes dramatically but researchers don't yet understand all the underlying mechanisms.

7 Feb 2024

New tool can help researchers to better understand the metabolism of microorganisms

Researchers from University of California San Diego, as part of a large collaboration with scientists around the world, have developed a new search tool to help researchers better understand the metabolism of microorganisms.

6 Feb 2024

Burn injury disrupts the intestinal mucus barrier and alters gut microbiota, study reveals

On a study (doi:10.1093/burnst/tkad056) published in the journal Burns & Trauma, researchers employed a combination of techniques to analyze the effects of burn injury on the gut microbiota and mucus barrier in mice.

6 Feb 2024

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

Metabolites News and Research

Study discovers link between a breakdown product from excess niacin and heart disease

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Healthy lifestyles linked to specific metabolic markers, large study finds

Twin study investigates the role of the microbiome as a modifier in mental disorders

Groundbreaking model predicts heart attack risk months in advance

Black cumin: Ancient superseed with modern health benefits

Microgreens: Superfoods for the future, packed with nutrients and easy to grow

Beyond just a berry: The multifaceted health benefits of black chokeberry

Blueberries boost calmness but not cognition in metabolic syndrome study

Machine learning decodes data variations in metabolomics

Associations between ultra-processed food consumption and phthalate exposures in pregnant women

Pregnant women show significant immune system changes linked to gut microbiome

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

Rucaparib and its major metabolite exhibit differential biological activity and synergy

New study links legume consumption to lower risk of colorectal cancer

Study finds gut health key to combating skin diseases, eyes probiotics as potential treatment

Gut microbiota alterations may influence immune system changes during pregnancy

New tool can help researchers to better understand the metabolism of microorganisms

Burn injury disrupts the intestinal mucus barrier and alters gut microbiota, study reveals

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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