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Antibiograms could improve antibiotic effectiveness, help address problems with antibiotic resistance

Antibiograms could improve antibiotic effectiveness, help address problems with antibiotic resistance

Use of "antibiograms" in skilled nursing facilities could improve antibiotic effectiveness and help address problems with antibiotic resistance that are becoming a national crisis, researchers conclude in a new study. [More]
Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

In multiple sclerosis, the immune system goes rogue, improperly attacking the body's own central nervous system. Mobility problems and cognitive impairments may arise as the nerve cells become damaged. [More]
Salivary mucins protect teeth from cariogenic bacterium

Salivary mucins protect teeth from cariogenic bacterium

Salivary mucins, key components of mucus, actively protect the teeth from the cariogenic bacterium, Streptococcus mutans, according to research published ahead of print in Applied and Environmental Microbiology. The research suggests that bolstering native defenses might be a better way to fight dental caries than relying on exogenous materials, such as sealants and fluoride treatment, says first author Erica Shapiro Frenkel, of Harvard University, Cambridge, MA. [More]
UF Health researcher finds way to grow human norovirus

UF Health researcher finds way to grow human norovirus

Noroviruses are pernicious intestinal viruses. They cause violent vomiting and diarrhea, and people ill with the virus remain contagious up to three days after they seem to recover. [More]
New vaccination approach can reduce tumor burden, suppress formation of lung metastases

New vaccination approach can reduce tumor burden, suppress formation of lung metastases

In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous lung metastases in a mouse model for metastatic breast cancer. [More]
Findings pave way for personalized probiotic therapies for obesity-related diseases

Findings pave way for personalized probiotic therapies for obesity-related diseases

Our genetic makeup influences whether we are fat or thin by shaping which types of microbes thrive in our body, according to a Cornell-led study published today in the journal Cell. [More]
Cellular and Molecular Gastroenterology and Hepatology joins AGA's other peer-reviewed journals

Cellular and Molecular Gastroenterology and Hepatology joins AGA's other peer-reviewed journals

The American Gastroenterological Association is pleased to welcome a new member to its family of journals: Cellular and Molecular Gastroenterology and Hepatology (CMGH). CMGH will showcase cutting-edge digestive biology research in a digital open-access format. [More]
Non-injectable vaccine may provide long-term protection against deadly Ebola virus

Non-injectable vaccine may provide long-term protection against deadly Ebola virus

A potentially breathable, respiratory vaccine in development has been shown to provide long-term protection for non-human primates against the deadly Ebola virus, as reported this week in the online edition of the journal Molecular Pharmaceutics. [More]
Research findings could pave way for new treatments against filoviruses

Research findings could pave way for new treatments against filoviruses

Filoviruses like Ebola "edit" genetic material as they invade their hosts, according to a study published this week in mBio, the online open-access journal of the American Society for Microbiology. [More]
Researchers develop new test to identify drugs that could work against Lyme disease

Researchers develop new test to identify drugs that could work against Lyme disease

Researchers from the Johns Hopkins Bloomberg School of Public Health have developed a test they say will allow them to test thousands of FDA-approved drugs to see if they will work against the bacteria that causes tick-borne Lyme disease. [More]
Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year. [More]
New NIH award aims to help increase diversity in biomedicine

New NIH award aims to help increase diversity in biomedicine

The University of Alaska Fairbanks received a $23.8 million, five-year award from the National Institutes of Health to launch a new undergraduate program that will engage students from diverse backgrounds, especially those from rural Alaska, in biomedical research as a way to foster their interest and success in biomedical and health careers. [More]
New test could help physicians predict people who are at early stages of sepsis

New test could help physicians predict people who are at early stages of sepsis

A new test, developed by University of British Columbia researchers, could help physicians predict within an hour if a patient will develop severe sepsis so they can begin treatment immediately. [More]
Human trial of second investigational Ebola vaccine candidate under way

Human trial of second investigational Ebola vaccine candidate under way

Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health's Clinical Center in Bethesda, Maryland. [More]
Novel approach may help detect invasive aspergillosis

Novel approach may help detect invasive aspergillosis

Many different microbes can cause pneumonia, and treatment may be delayed or off target if doctors cannot tell which bug is the culprit. A novel approach—analyzing a patient's breath for key chemical compounds made by the infecting microbe—may help detect invasive aspergillosis, a fungal infection that is a leading cause of mortality in patients with compromised immune systems, according to a proof-of-concept study now online in Clinical Infectious Diseases. [More]
Lactobacillus-containing probiotics can improve lupus symptoms

Lactobacillus-containing probiotics can improve lupus symptoms

Lactobacillus species, commonly seen in yogurt cultures, correlate, in the guts of mouse models, with mitigation of lupus symptoms, while Lachnospiraceae, a type of Clostridia, correlate with worsening, according to research published ahead of print in Applied and Environmental Microbiology. [More]
Antibiotic-resistant bacteria share resources to cause chronic infections, show studies

Antibiotic-resistant bacteria share resources to cause chronic infections, show studies

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt University investigators have discovered. [More]

Ebola Virus and Public Health: A special feature by Disaster Medicine and Public Health

Accurate knowledge regarding Ebola is critical and pertinent for practicing physicians and clinicians given the current risk of hazardous global outbreak and epidemic. [More]
New oral biologic medication successfully treats precancerous intestinal inflammation

New oral biologic medication successfully treats precancerous intestinal inflammation

An oral biologic medication has successfully treated chronic, precancerous inflammation in the intestine, according to results of an animal study authored by an MD/PhD student in the University at Buffalo School of Medicine and Biomedical Sciences. [More]
Research initiative focuses on microbial characteristics of Staphylococcus aureus

Research initiative focuses on microbial characteristics of Staphylococcus aureus

Staphylococcus aureus (Sa) and methicillin-resistant staph aureus (MRSA) continue to be among the most common pathogens that overwhelm the immune system, causing serious skin, soft tissue and life-threatening blood-borne infections. [More]