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New research shows independent gut-to-brain and brain-to-gut pathways operate in IBS patients

New research shows independent gut-to-brain and brain-to-gut pathways operate in IBS patients

New research indicates that in patients with irritable bowedistinct brain-to-gut pathway, where psychological symptoms begin first, and separately a distinctl syndrome (IBS) or indigestion, there is a gut-to-brain pathway, where gut symptoms start first. [More]
Risk factors differ for early and delayed dementia after ICH

Risk factors differ for early and delayed dementia after ICH

Acute haematoma parameters predict the onset of dementia in the first 6 months after intracerebral haemorrhage, but not that of delayed dementia, report researchers. [More]
Formal mental health therapies offer little relief from postpartum depression for low-income mothers of color

Formal mental health therapies offer little relief from postpartum depression for low-income mothers of color

Health care providers and human service agencies often manage postpartum depression with formal mental health treatments and antidepressant therapies, but for new, low-income mothers of color these interventions often provide little relief from the mood disorder that sometimes follows childbirth, according to a new study led by a University at Buffalo researcher. [More]
Depression, anxiety co-occur in bipolar disorder patients following mania

Depression, anxiety co-occur in bipolar disorder patients following mania

Adults with bipolar disorder are just as likely to develop anxiety as depression following an episode of mania, according to data from a national survey of more than 34,000 adults. This finding, published today in Molecular Psychiatry, may expand our understanding of bipolar disorder to include anxiety. [More]
FDA proposes to change regulation of ECT treatment

FDA proposes to change regulation of ECT treatment

For decades, people with severe depression, bipolar disorder, and other major mental health conditions have gotten help from the treatment known as ECT, when nothing else helped them. [More]
Mood disorder experts question effectiveness of metyrapone drug

Mood disorder experts question effectiveness of metyrapone drug

Pioneering research by mood disorder experts at Newcastle University has questioned the effectiveness of metyrapone, a drug suggested to treat depression. [More]
Long-term lithium exposure does not increase renal dysfunction risk

Long-term lithium exposure does not increase renal dysfunction risk

Stable lithium maintenance therapy does not increase the risk of renal dysfunction in patients with bipolar affective disorder, findings from a population-based study suggest. [More]
Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

Neurocrine Biosciences, Inc. announced today that NBI-98854, a highly selective small molecule VMAT2 inhibitor, showed a statistically significant reduction in tardive dyskinesia during the six weeks of placebo-controlled treatment in the Kinect 3 clinical trial. This Phase III trial included moderate to severe tardive dyskinesia patients with underlying schizophrenia, schizoaffective disorder, bipolar or major depressive disorder. [More]
Aphantasia: A condition that describes people born with diminished visual imagery ability

Aphantasia: A condition that describes people born with diminished visual imagery ability

If counting sheep is an abstract concept, or you are unable to visualise the faces of loved ones, you could have aphantasia - a newly defined condition to describe people who are born without a "mind's eye". [More]
Neurocrine completes enrollment in Phase III clinical trial of NBI-98854 in tardive dyskinesia patients

Neurocrine completes enrollment in Phase III clinical trial of NBI-98854 in tardive dyskinesia patients

Neurocrine Biosciences, Inc. announced today that it has recently completed subject randomization of the Phase III clinical trial (Kinect 3 Study) of its proprietary Vesicular Mono-Amine Transporter 2 (VMAT2) compound NBI-98854 in tardive dyskinesia patients. [More]
Allergan announces U.S. availability of SAPHRIS 2.5 mg tablets for children with bipolar I disorder

Allergan announces U.S. availability of SAPHRIS 2.5 mg tablets for children with bipolar I disorder

Allergan plc today announced that SAPHRIS (asenapine) 2.5 mg sublingual (placed under the tongue) black-cherry flavored tablets are available in pharmacies throughout the U.S. In March 2015, the U.S. Food and Drug Administration approved SAPHRIS for the acute treatment of manic or mixed episodes associated with bipolar I disorder in pediatric patients (ages 10 – 17). [More]
SUNY Downstate Medical Center researchers identify ALPIM syndrome as new spectrum disorder

SUNY Downstate Medical Center researchers identify ALPIM syndrome as new spectrum disorder

The relationship between mental and physical health is well established. But when mental and physical illnesses co-occur, patients' accounts of physical illness are sometimes arbitrarily discredited or dismissed by physicians. [More]
People with recurrent depression have significantly smaller hippocampus than healthy individuals

People with recurrent depression have significantly smaller hippocampus than healthy individuals

The brains of people with recurrent depression have a significantly smaller hippocampus - the part of the brain most associated with forming new memories - than healthy individuals, a new global study of nearly 9,000 people reveals. [More]
New study shows that depression can make your brain go 'fuzzy'

New study shows that depression can make your brain go 'fuzzy'

People with depression or bipolar disorder often feel their thinking ability has gotten "fuzzy", or less sharp than before their symptoms began. Now, researchers have shown in a very large study that effect is indeed real - and rooted in brain activity differences that show up on advanced brain scans. [More]
Study assesses factors that lead to inaccurate detection of frequency, duration of AF episodes

Study assesses factors that lead to inaccurate detection of frequency, duration of AF episodes

A new study shows how specific factors such as gender, age and mood disorders like anxiety and depression can lead patients with atrial fibrillation (AF) to inaccurately assess their heart rhythm. [More]
Yoga could help reduce depression in pregnant women

Yoga could help reduce depression in pregnant women

In a small pilot study, researchers at Brown University, Butler Hospital, and Women & Infants' Hospital have found evidence suggesting that yoga could help pregnant women with significant depression reduce the severity of the mood disorder. [More]
Chronic pain common in affective disorders

Chronic pain common in affective disorders

Patients with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, research shows. [More]
Women with postpartum depression during pregnancy may face greater risk, study finds

Women with postpartum depression during pregnancy may face greater risk, study finds

When it comes to postpartum depression, one size does not fit all, according to a new study led by University of North Carolina School of Medicine researchers. [More]

UC Berkeley study finds self-worth key to diagnoses of psychopathologies

Donald Trump's ego may be the size of his financial empire, but that doesn't mean he's the picture of mental health. The same can be said about the self-esteem of people who are living from paycheck to paycheck, or unemployed. New research from the University of California, Berkeley, underscores this mind-wallet connection. [More]
Psychopathology persists in ultra-high-risk psychosis patients

Psychopathology persists in ultra-high-risk psychosis patients

Patients at ultra-high-risk for psychosis frequently have nonpsychotic disorders and often continue to experience attenuated psychotic symptoms, even if they do not transition to clinical psychosis, a study shows. [More]
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