Mood Stabilisers News and Research

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Clinical pointers to bipolar, unipolar depression confirmed

A large study confirms several factors that can distinguish patients with bipolar depression from those with unipolar depression, including higher trait impulsivity, aggression and hostility.

10 Oct 2014

Clinical practice study supports ISBD recommendations

Findings in patients with bipolar disorder given short-term antidepressant treatment support the recent International Society for Bipolar Disorder’s task force recommendations.

2 Oct 2014

Social environment may influence mood stabiliser adherence

The attitudes of patients with bipolar disorder towards mood-stabilising medications are influenced by their social support system, say researchers.

3 Jul 2014

Study: Use of antipsychotic medication during pregnancy can affect babies

A seven-year study of women who take antipsychotic medication while pregnant, proves it can affect babies.

3 Jun 2014

Bipolar remission influenced by anxiety and OCD

Anxiety disorders and obsessive compulsive disorder may reduce the likelihood of achieving remission for patients with bipolar disorder, study findings indicate.

29 May 2014

Antipsychotic use linked to reduced patient violence

Prescribing antipsychotics may reduce psychiatric patients’ propensity to commit violent crime, a study in The Lancet suggests.

14 May 2014

Antipsychotic medication can reduce violent crime among people with psychiatric illness

New data indicate that people with psychiatric illness are almost half as likely to commit a violent crime when taking antipsychotic medication (such as clozapine or risperidone) compared with when they are not using such medication. The reduction in violent crime was smaller with use of mood stabilising drugs (such as lithium or carbamazepine) and only apparent among male patients with bipolar disorder.

9 May 2014

Antipsychotic medication reduces violent crime rates

People who use antipsychotic medication (such as clozapine or risperidone) to treat psychiatric illness are nearly half as likely to commit a violent crime compared to when they are not using such medication, according to new results published in The Lancet.

8 May 2014

Excessive alcohol use does not alter course of bipolar mood states

Patients with bipolar disorder who consume alcohol do not experience significant changes in their self-reported mood states with increased consumption, show Dutch study findings.

3 Apr 2014

Support for progranulin role in bipolar disorder

Researchers have found reduced levels of plasma progranulin in patients with bipolar disorder, strengthening evidence for its possible role as a biomarker for the condition.

20 Feb 2014

Interhemispheric disconnectivity highlighted in bipolar disorder

Research shows that patients with bipolar I disorder have reduced white matter integrity, including in the corpus callosum, which connects the brain’s hemispheres.

18 Feb 2014

Risk for adverse pregnancy outcomes increased in bipolar women

Women with bipolar disorder are at increased risk for adverse pregnancy outcomes, results from a Swedish study show.

16 Nov 2012

People with manic depression have a distinct chemical signature in their brains

People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause.

5 Feb 2008

New hope for people with bipolar disorder

Melbourne mental health researchers have succeeded in halving the number of relapses experienced by people with bipolar disorder which strikes two in 100 Australians, accounts for 12 per cent of suicides each year and costs the country at least $1.5 billion annually.

24 Aug 2007