Movement disorders News and Research

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Mobile memory tests offer new hope for Alzheimer's detection

Dedicated memory tests on smartphones enable the detection of "mild cognitive impairment", a condition that may indicate Alzheimer's disease, with high accuracy.

27 Mar 2024

Towards better diagnosis of neurodegenerative disorders: Skin biopsy for α-synuclein detection proves effective

The positivity rate of cutaneous phosphorylated alpha-synuclein protein (P-SYN) deposition among individuals with dementia.

26 Mar 2024

Study finds higher burden of neurologic disease after influenza than COVID-19 hospitalization

People who have an influenza infection are more likely to need medical care for neurologic disorders within the next year than people who have a COVID-19 infection, according to a study published in the March 20, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024

Innovative levodopa infusion pump trial shows promise for reducing Parkinson's symptoms

An international, multisite phase 3 trial co-led by a University of Cincinnati researcher found Parkinson's disease medication delivered through an infusion pump is safe and effective at reducing symptoms for longer periods of time.

15 Mar 2024

PFAS chemicals in the blood are linked with increased risk of cardiovascular diseases

Researchers at DZNE provide evidence that traces of the widely used PFAS chemicals in human blood are associated with unfavorable lipid profiles and thus with an increased risk of cardiovascular diseases.

11 Mar 2024

Unraveling typical disease trajectories in multimorbid patients from birth to death

In a recent study published in npj Digital Medicine, Complexity Science Hub researchers analyzed a comprehensive dataset of 44 million hospital stays in Austria.

7 Mar 2024

Using deep brain stimulation to map dysfunctional brain circuits linked to four disorders

Mass General Brigham researchers identified sets of connections that are disrupted and malfunctioning as a consequence of Parkinson’s disease, dystonia, obsessive compulsive disorder and Tourette's syndrome.

24 Feb 2024

Mapping the human dysfunctome with deep brain stimulation

A new study led by investigators from Mass General Brigham demonstrated the use of deep brain stimulation (DBS) to map a 'human dysfunctome' -; a collection of dysfunctional brain circuits associated with different disorders.

22 Feb 2024

Scientists discover key pathway linking brain's habit center and motor learning region

Researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc).

29 Jan 2024

SynNeurGe: A new biological classification system for Parkinson's disease research

One of the things that makes developing effective treatments for Parkinson's disease so challenging is its complexity.

23 Jan 2024

Researchers propose a new model for classifying Parkinson's disease

An international research team led by Krembil Brain Institute Neurologist and Senior Scientist, Dr. Anthony Lang, has proposed a new model for classifying Parkinson's disease (PD).

23 Jan 2024

New ultrasound technology shows promise for preventing brain damage in premature and sick infants

Ultrasound technology developed at the Norwegian University of Science and Technology (NTNU) makes it possible to monitor cerebral blood flow in newborn babies, helping prevent brain damage in premature and sick infants who require surgery.

2 Jan 2024

Hackensack Meridian's Dr. Mary Sedarous wins ALS United Mid-Atlantic's Flame of Hope Award

Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center's Mary Sedarous, M.D., medical director of the ALS Center, was honored at ALS United Mid-Atlantic's 2023 Annual Celebration with the organization's Flame of Hope Award, recognizing research and innovation.

26 Dec 2023

Words matter: Delivering Parkinson's diagnosis with empathy and hope

As Parkinson's disease diagnoses continue to rise in the U.S., limited patient access to movement disorder specialists means the job of delivering the often-devastating, lifechanging news falls on primary care physicians or community neurologists who may not have the necessary expertise for this sensitive task.

21 Dec 2023

ChatGPT models excel in neurology exam, surpassing human student performance

Study shows two ChatGPT large language models (LLMs) outperformed human neurology students in an entrance exam, with one model achieving 85% accuracy, demonstrating their potential in clinical neurology and medical education.

10 Dec 2023

Working night shifts associated with higher occurrence of disordered sleep

Sleep is critical for daytime and neurocognitive functioning, as well as physical and mental health. When people work shifts – in 2015, 21% of workers in the European Union did – their circadian sleep-wake rhythms are commonly disrupted.

7 Dec 2023

Photobiomodulation shows promise as safe and tolerable adjunct therapy for Parkinson's Disease, recent trial suggests

A safe and feasible treatment option for reducing the motor signs of Parkinson's disease.

5 Dec 2023

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women's increased risk for the disease and its severity.

21 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023