Multiple Sclerosis News and Research RSS Feed - Multiple Sclerosis News and Research

Multiple sclerosis (MS) is a severe autoimmune disease of the central nervous system that affects the brain and spinal cord, causing problems with muscle movement, balance and vision.

In MS, the protein coating called myelin, which protects nerves and helps electrical signals travel from the brain to the rest of the body, is damaged. The immune system, which usually fights infection, mistakes myelin for a foreign body and attacks it, stripping it from around the nerves. Exactly what causes this abnormal immune response is unclear, but research suggests a combination of both genetic and environmental factors.

The damaged myelin disrupts the transfer of nerve signals which may slow down, become distorted or stop altogether. This can cause severe symptoms ranging from vision loss through to muscle stiffness, loss of control over muscle movement, difficulties with balance and poor co-ordination.

Around 100,000 people in the UK have MS and it affects about three times as many women as men. The usual age at which diagnosis occurs is around 30, however, symptoms often first develop between the ages of 15 and 45.

Currently, there is no cure for MS but therapeutic approaches such as physiotherapy and steroid injections are used to manage the condition and ease symptoms.
Existing drug could help treat MS, other neurological diseases

Existing drug could help treat MS, other neurological diseases

Damage to myelin, the fatty insulator that enables communication between nerve cells, characterizes multiple sclerosis (MS) and other devastating neurological diseases. [More]
TREM2 protein may help slow progression of multiple sclerosis, Alzheimer's disease

TREM2 protein may help slow progression of multiple sclerosis, Alzheimer's disease

Highlighting a potential target in the treatment of multiple sclerosis (MS) and Alzheimer's disease, new research suggests that triggering a protein found on the surface of brain cells may help slow the progression of these and other neurological diseases. [More]
Henry Ford researchers propose new treatment strategy for stroke, other neurological disorders

Henry Ford researchers propose new treatment strategy for stroke, other neurological disorders

Medicine should reconsider how it treats stroke and other neurological disorders, focusing on the intrinsic abilities of the brain and nervous system to heal themselves rather than the "modest" benefits of clot-busting drugs and other neuroprotective treatments. [More]

Study shows importance of disclosing physician conflicts of interest in MS ISCTs to potential participants

If you're one of the nearly half a million Americans living with multiple sclerosis (MS) - a slowly disabling disease of the central nervous system - you are likely dependent on disease-modifying drugs to prevent symptoms such as vision problems, balance issues and weakness. Often, these treatments have been developed through pharmaceutical industry-sponsored clinical trials (ISCT) in collaboration with academic or private practice physicians who care for MS patients. [More]
New pharmacological compounds block nerve cell damage in mouse models of MS

New pharmacological compounds block nerve cell damage in mouse models of MS

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience. [More]
Drinking coffee may lower risk of developing multiple sclerosis

Drinking coffee may lower risk of developing multiple sclerosis

Drinking coffee may be associated with a lower risk of developing multiple sclerosis (MS), according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015. [More]
Sleeping more than eight hours a night could increase risk of stroke

Sleeping more than eight hours a night could increase risk of stroke

People who sleep more than eight hours a night may have an increased risk of stroke, according to a new study published in the February 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
New skin test may help detect abnormal proteins in patients with Alzheimer's and Parkinson's diseases

New skin test may help detect abnormal proteins in patients with Alzheimer's and Parkinson's diseases

Scientists have discovered a skin test that may shed new light on Alzheimer's and Parkinson's diseases, according to a study released today will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, D.C., April 18 to 25, 2015. [More]
People who exhibit resistance to aspirin may be at risk of more severe strokes

People who exhibit resistance to aspirin may be at risk of more severe strokes

People who exhibit a resistance to aspirin may be more likely to have more severe strokes than people who still respond to the drug, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015. [More]
LSU Health New Orleans finalizes deal with CB BioSciences

LSU Health New Orleans finalizes deal with CB BioSciences

The Office of Technology Management at LSU Health New Orleans has finalized a deal with CB BioSciences, Inc., a startup drug development company to build a platform around the intellectual property portfolio of Chu Chen, PhD, LSU Health New Orleans Professor of Neuroscience. [More]
Christopher & Dana Reeve Foundation announces Quality of Life grants for 75 nonprofit organizations

Christopher & Dana Reeve Foundation announces Quality of Life grants for 75 nonprofit organizations

The Christopher & Dana Reeve Foundation, a leading nonprofit dedicated to improving quality of life for individuals living with paralysis, announced it has awarded $600,137 in Quality of Life grants to 75 nonprofit organizations nationwide. [More]
Case Western dental researcher discovers new way to model how T cells cause inflammation in mice

Case Western dental researcher discovers new way to model how T cells cause inflammation in mice

Case Western Reserve University dental researcher Pushpa Pandiyan has discovered a new way to model how infection-fighting T cells cause inflammation in mice. [More]
Virus that causes chicken pox and shingles linked to giant cell arteritis

Virus that causes chicken pox and shingles linked to giant cell arteritis

A new study developed at the University of Colorado School of Medicine at the Anschutz Medical Campus links the virus that causes chicken pox and shingles to a condition that inflames blood vessels on the temples and scalp in the elderly, called giant cell arteritis. [More]
Women with multiple sclerosis may have lower levels of antioxidant, anti-inflammatory nutrients

Women with multiple sclerosis may have lower levels of antioxidant, anti-inflammatory nutrients

Women with multiple sclerosis (MS) may have lower levels of important antioxidant and anti-inflammatory nutrients, such as folate from food and vitamin E, than healthy people, according to a new study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015. [More]
New study links chicken pox and shingles virus to giant cell arteritis in elderly

New study links chicken pox and shingles virus to giant cell arteritis in elderly

A new study links the virus that causes chicken pox and shingles to a condition that inflames blood vessels on the temples and scalp in the elderly, called giant cell arteritis. The study is published in the February 18, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. The condition can cause sudden blindness or stroke and can be life-threatening. [More]
Natalizumab drug helps scientists confirm how 'viral reservoirs' form in HIV patients

Natalizumab drug helps scientists confirm how 'viral reservoirs' form in HIV patients

A drug used to treat patients with Crohn's disease and multiple sclerosis has helped scientists confirm how "viral reservoirs" form in patients living with HIV and also proven effective in animal trials at blocking the pathways to those reservoirs in the brain and gut, a team of researchers reported recently in the journal PLOS Pathogens. [More]
New treatment may bring hope for people suffering from muscle cramps

New treatment may bring hope for people suffering from muscle cramps

A new treatment may bring hope for people who suffer from muscle cramps or spasms from neuromuscular disorders, diseases such as multiple sclerosis or simply from nighttime leg cramps that keep people from sleeping, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015. [More]
Regulus Therapeutics reports net loss of $22.2 million for fourth quarter 2014

Regulus Therapeutics reports net loss of $22.2 million for fourth quarter 2014

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today reported financial results for the fourth quarter and year ended December 31, 2014, including a summary of recent corporate highlights. [More]
Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Scientists at Trinity College Dublin have uncovered a marvel molecule that blocks a key driver of inflammatory diseases. The finding could meet a major unmet clinical need by inspiring new non-invasive treatments for arthritis, multiple sclerosis and Muckle-Wells syndrome, among a myriad of other inflammatory diseases. [More]
CAMH scientists discover potential new approach to treat multiple sclerosis

CAMH scientists discover potential new approach to treat multiple sclerosis

Scientists at the Centre for Addiction and Mental Health have discovered a promising new approach to treat multiple sclerosis (MS). In a new study, they've identified a previously unknown change in the spinal cord related to MS, and a way to alter this change to reduce the nerve cell damage that occurs with the disease. [More]