Multiple Sclerosis News and Research RSS Feed - Multiple Sclerosis News and Research

Multiple sclerosis (MS) is a severe autoimmune disease of the central nervous system that affects the brain and spinal cord, causing problems with muscle movement, balance and vision.

In MS, the protein coating called myelin, which protects nerves and helps electrical signals travel from the brain to the rest of the body, is damaged. The immune system, which usually fights infection, mistakes myelin for a foreign body and attacks it, stripping it from around the nerves. Exactly what causes this abnormal immune response is unclear, but research suggests a combination of both genetic and environmental factors.

The damaged myelin disrupts the transfer of nerve signals which may slow down, become distorted or stop altogether. This can cause severe symptoms ranging from vision loss through to muscle stiffness, loss of control over muscle movement, difficulties with balance and poor co-ordination.

Around 100,000 people in the UK have MS and it affects about three times as many women as men. The usual age at which diagnosis occurs is around 30, however, symptoms often first develop between the ages of 15 and 45.

Currently, there is no cure for MS but therapeutic approaches such as physiotherapy and steroid injections are used to manage the condition and ease symptoms.
Perrigo: Shareholders may reject Mylan' offer

Perrigo: Shareholders may reject Mylan' offer

Perrigo Company plc today commented on the Mylan N.V. shareholder vote regarding its planned unsolicited offer to acquire Perrigo. [More]

Perrigo closes acquisition of leading OTC brands from GSK

Perrigo Company plc today announced that it has completed the acquisition of leading OTC brands from GSK in an all cash transaction valued at €200 million. The transaction is a clear demonstration of Perrigo's unique ability to maximize brand value across the Company's leading European distribution network spanning 36 countries. [More]

Cryoport to support future clinical trials for Opexa's personalized T-cell immunotherapy programs for MS, NMO

Cryoport, Inc., the leading provider of advanced cryogenic logistics solutions for the life sciences industry, today announced that its validated cryogenic logistics solution will support future clinical trials for Opexa Therapeutics' lead personalized T-cell immunotherapy programs for Multiple Sclerosis ("MS") and Neuromyelitis Optica ("NMO"). [More]
Dementia sufferers may begin to lose awareness of memory problems 2-3 years before onset

Dementia sufferers may begin to lose awareness of memory problems 2-3 years before onset

People who will develop dementia may begin to lose awareness of their memory problems two to three years before the actual onset of the disease, according to a new study published in the August 26, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Mental visual imagery training may improve AM/EFT functioning in RR-MS patients

Mental visual imagery training may improve AM/EFT functioning in RR-MS patients

Patients with relapsing-remitting multiple sclerosis (RR-MS), the most common form of the disease, often have deficits in two neuropsychological functions, autobiographical memory (AM) and episodic future thinking (EFT), which impact quality of life. [More]
Cognitive factors associated with activity, participation in everyday life among people with MS

Cognitive factors associated with activity, participation in everyday life among people with MS

Kessler Foundation researchers found that processing speed is the primary limiting factor associated with activity and participation in everyday life among people with multiple sclerosis (MS). "Factors that moderate activity limitation and participation restriction in people with multiple sclerosis" was published in the American Journal of Occupational Therapy. [More]
Stress hormone cortisol tied to thinking problems in healthy older people

Stress hormone cortisol tied to thinking problems in healthy older people

Testing the saliva of healthy older people for the level of the stress hormone cortisol may help identify individuals who should be screened for problems with thinking skills, according to a study published in the August 19, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Early exposure to inflammatory cytokines can paralyze CD4 T cells

Early exposure to inflammatory cytokines can paralyze CD4 T cells

In a discovery that is likely to rewrite immunology text books, researchers at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can "paralyze" CD4 T cells, immune components that help orchestrate the body's response to pathogens and other invaders. [More]
Survey identifies key factors linked to pediatric safety events in out-of-hospital emergent care situations

Survey identifies key factors linked to pediatric safety events in out-of-hospital emergent care situations

A national survey of more than 750 emergency medical services providers conducted by researchers at Oregon Health & Science University identified airway management skills, personal anxiety and limited pediatric care proficiency among key factors that may contribute to pediatric safety events for children in out-of-hospital emergent care situations. [More]
Physical activity linked to reduced paediatric MS burden

Physical activity linked to reduced paediatric MS burden

A cross-sectional study has found an association between moderate or strenuous physical activity and reduced fatigue, lesion volumes and relapse rates in children and adolescents with multiple sclerosis. [More]
Nuclear process in the brain may play critical role in health and disease

Nuclear process in the brain may play critical role in health and disease

Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped brain cell, called an astrocyte, may play a critical role in health and disease. [More]
Kessler Foundation researcher confirms link between sleep disturbances and MS-related fatigue

Kessler Foundation researcher confirms link between sleep disturbances and MS-related fatigue

Kessler Foundation's Lauren Strober, PhD, explores the association of secondary fatigue and sleep disturbances in multiple sclerosis (MS). "Fatigue in multiple sclerosis: a look at the role of poor sleep" was published in Frontiers in Neurology. [More]
Inhibikase Therapeutics launches observational clinical study in patients who survived PML

Inhibikase Therapeutics launches observational clinical study in patients who survived PML

Inhibikase Therapeutics, Inc. announces the launch of an observational clinical study in patients who contracted Progressive Multifocal Leukoencephalopathy (PML), the rare and often fatal brain infection that arises as an unintended side effect of some medications used for treatment of Multiple Sclerosis, Crohn's disease, Ulcerative Colitis and certain cancers of the blood and lymph. [More]
Netrin1 protein acts as cellular "marriage broker"

Netrin1 protein acts as cellular "marriage broker"

Scientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and the McGill University Health Centre, have made a breakthrough in understanding an important protein that appears to act as a kind of cellular "marriage broker." [More]
Regular exercise benefits children with multiple sclerosis

Regular exercise benefits children with multiple sclerosis

A new study suggests children with multiple sclerosis (MS) who exercise regularly may have a less active disease. The research is published in the August 12, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Intrexon, Synthetic Biologics form ECC to develop and commercialize novel biotherapeutics for phenylketonuria

Intrexon, Synthetic Biologics form ECC to develop and commercialize novel biotherapeutics for phenylketonuria

Intrexon Corporation, a leader in synthetic biology, and Synthetic Biologics, Inc., a clinical-stage company focused on developing therapeutics to protect the microbiome while targeting pathogen-specific diseases, today announced an Exclusive Channel Collaboration (ECC) to pursue the development and commercialization of novel biotherapeutics for the treatment of patients with phenylketonuria (PKU), a serious and debilitating metabolic disorder. [More]
Researchers develop new technology to track DNA-protein binding in live cells

Researchers develop new technology to track DNA-protein binding in live cells

Researchers have developed a new technology that precisely marks where groups of regulatory proteins called transcription factors bind DNA in the nuclei of live cells. [More]
Diets high in sodium could be a novel risk factor in development of multiple sclerosis

Diets high in sodium could be a novel risk factor in development of multiple sclerosis

Here's another reason to put the salt shaker down: New research in mice shows that diets high in sodium may be a novel risk factor in the development of multiple sclerosis (MS) by influencing immune cells that cause the disease. Although this research does implicate salt intake as a risk factor, it is important to note that dietary salt is likely just one of the many environmental factors contributing to this complex disease, and very much influenced by one's genetic background. [More]
Poor relapse recovery heralds progressive MS

Poor relapse recovery heralds progressive MS

Multiple sclerosis patients with poor recovery from relapses develop the progressive form faster than those with good recovery, research shows. [More]
Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Half of patients referred to a specialist centre with a diagnosis of chronic inflammatory demyelinating polyneuropathy do not actually have the condition, report researchers. [More]
Advertisement