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New study examines efficacy of brace application for treatment of spinal compression fractures

New study examines efficacy of brace application for treatment of spinal compression fractures

Compression fractures in the spine due to osteoporosis, a common condition causing progressive bone loss and increased fracture risk, are especially common in older women. A new study appearing in the December 3rd issue of the Journal of Bone & Joint Surgery found that patients who wore a brace as treatment for a spinal compression fracture had comparable outcomes in terms of pain, function and healing when compared to patients who did not wear a brace. [More]
Adequate levels of vitamin E critical for young, elderly and pregnant women

Adequate levels of vitamin E critical for young, elderly and pregnant women

Amid conflicting reports about the need for vitamin E and how much is enough, a new analysis published today suggests that adequate levels of this essential micronutrient are especially critical for the very young, the elderly, and women who are or may become pregnant. [More]
Comprehensive fitness and nutrition regimens may prevent bone and muscle deterioration

Comprehensive fitness and nutrition regimens may prevent bone and muscle deterioration

Being physically active may significantly improve musculoskeletal and overall health, and minimize or delay the effects of aging, according to a review of the latest research on senior athletes (ages 65 and up) appearing in the September issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS). [More]
Novogen receives funding support to commence studies in muscular dystrophy

Novogen receives funding support to commence studies in muscular dystrophy

The Australian biotechnology company, Novogen Limited today announced receipt of funding from the FSHD Global Research Foundation as part of the Company’s efforts to find effective treatments for a range of musculo-degenerative diseases including facioscapulohumeral dystrophy (FSHD). [More]
Sildenafil may help boys suffering from muscular dystrophy disease

Sildenafil may help boys suffering from muscular dystrophy disease

Drugs used to treat erectile dysfunction may be able to slow disease progression in boys who suffer from the muscle wasting disease Duchenne muscular dystrophy. [More]
IRB Barcelona scientists develop new drug target to prevent muscle deterioration in certain diseases

IRB Barcelona scientists develop new drug target to prevent muscle deterioration in certain diseases

​In the study published today in the Journal of Clinical Investigation (JCI), one of the journals with highest impact in experimental medicine, the researchers associate the activity of the DOR protein with muscle atrophy and point to DOR as a plausible target against which to develop a drug to prevent muscle deterioration in certain diseases. [More]
Muscle atrophy therapy: an interview with Dr. Levine, Clinical Associate Professor at Temple University School of Medicine

Muscle atrophy therapy: an interview with Dr. Levine, Clinical Associate Professor at Temple University School of Medicine

Atrophy is loss of muscle which can occur in response to either pain or trauma. When you stop using something like muscle it gets weaker. [More]
Duke researchers find novel way to repair gene responsible for Duchenne muscular dystrophy

Duke researchers find novel way to repair gene responsible for Duchenne muscular dystrophy

Using a novel genetic 'editing' technique, Duke University biomedical engineers have been able to repair a defect responsible for one of the most common inherited disorders, Duchenne muscular dystrophy, in cell samples from Duchenne patients. [More]
Ceramide might play a leading role in muscle deterioration in older adults

Ceramide might play a leading role in muscle deterioration in older adults

As men and women age, increasing quantities of fat tissue inevitably take up residence in skeletal muscle. A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults. [More]
Autoimmune disease myasthenia gravis halted in mice

Autoimmune disease myasthenia gravis halted in mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body. [More]
Gadd45a protein plays a key role in skeletal muscle atrophy

Gadd45a protein plays a key role in skeletal muscle atrophy

Whether you're old, have been ill, or suffered an injury, you've watched gloomily as your muscles have atrophied. The deterioration of muscle-even slight or gradual-is about as common to the human condition as breathing. [More]
Promising drug for Duchenne muscular dystrophy

Promising drug for Duchenne muscular dystrophy

Duchenne muscular dystrophy is a severely debilitating and lethal condition that affects 1 in 3,000. Females and males are affected, though females are rarely affected and are more often carriers. It is caused due to a defective gene that normally codes for the protein dystrophin, which helps provide a protective membrane around muscle fibers. Without this skin, muscle fibers become damaged and eventually die. [More]
Losartan therapy improves muscle injury regeneration and prevents disuse atrophy

Losartan therapy improves muscle injury regeneration and prevents disuse atrophy

Using geriatric mice, a Johns Hopkins research team has shown that losartan, a commonly used blood pressure drug, not only improves regeneration of injured muscle but also protects against its wasting away from inactivity. [More]
Tweaking gene in satellite cells may increase lifespan of people with muscular dystrophy

Tweaking gene in satellite cells may increase lifespan of people with muscular dystrophy

Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain. [More]
Nutritional supplements and seniors: New study

Nutritional supplements and seniors: New study

The University of Adelaide will be embarking on a new study that will look into the benefits of providing nutritional supplements and small doses of hormones to elderly people. [More]
Tel Aviv University uncovers muscle-stem cell mechanism in aging

Tel Aviv University uncovers muscle-stem cell mechanism in aging

Working out can help you shed pounds ― but that's just the beginning. New research from Tel Aviv University has found that "endurance exercises," like a Central Park jog or a spinning class, can make us look younger. The key, exercise, unlocks the stem cells of our muscles. [More]
Sangamo presents Phase 2 clinical data in ALS at Society for Neuroscience Meeting

Sangamo presents Phase 2 clinical data in ALS at Society for Neuroscience Meeting

Sangamo BioSciences, Inc. announced today the presentation of Phase 2 clinical data from its ZFP Therapeutic program to develop SB-509, a zinc finger protein transcriptional activator (ZFP-TF) of the vascular endothelial growth factor (VEGF)-A gene as a treatment for ALS. [More]
Northumbria University to host workshop on space exercise countermeasures and post mission rehabilitation

Northumbria University to host workshop on space exercise countermeasures and post mission rehabilitation

Space travel experts from around the world will gather at Northumbria University to discuss ways to tackle health issues faced by astronauts during lengthy extra terrestrial missions. [More]

Brown grants exclusive intellectual property license to Tivorsan Pharmaceuticals

Development of a potential treatment for the most common form of muscular dystrophy is moving into a new phase at Brown University. Brown has granted an exclusive license for the intellectual property to Tivorsan Pharmaceuticals, a startup firm that will strive to see it through human trials. [More]
Sticky protein protects cells from mechanical stress

Sticky protein protects cells from mechanical stress

A new study by scientists at the University of Iowa shows why muscle membranes don't rupture when healthy people exercise. [More]