Muscle Deterioration News and Research

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First comprehensive atlas sheds new light on processes underlying age-related muscle changes

How muscle changes with aging, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of aging muscles in humans.

15 Apr 2024

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

In a recent review published in Cell, a group of authors delved into the complexities of menopause, assessed its global impacts on health, and evaluated the effectiveness and safety of current treatments, emphasizing the importance of further research.

6 Sep 2023

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

10 Mar 2022

Study finds early stages of sarcopenia could be counteracted with timely interventions

Weakening muscles are a natural part of the ageing process, but for some people with a condition called sarcopenia the decline is abnormally fast.

30 Nov 2021

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Analysis of medical data from around 1800 65-year-old residents of Kobe, a large Japanese city, has shown that at least 3% have possible sarcopenia (*1), revealing that the risks are higher in those who are underweight and don't exercise enough.

24 Aug 2021

FDA approval provides targeted treatment option for patients with rare DMD mutation

Today, the U.S. Food and Drug Administration granted approval for Amondys 45 (casimersen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping (Exons are pieces of DNA that provide information for making proteins in a person's genome).

25 Feb 2021

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

Today, the U.S. Food and Drug Administration granted accelerated approval to Viltepso (viltolarsen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 53 skipping.

12 Aug 2020

Simple accelerometers improve diagnosis of Duchenne muscular dystrophy

Duchenne muscular dystrophy is the most common type of muscular dystrophy, affecting more than 10,000 males at birth per year in the United States with severe physical disability, chronic wasting and muscle deterioration.

11 Feb 2020

Carnegie biologists discover possible therapeutic target for slow healing of aged muscles

An age-related decline in recovery from muscle injury can be traced to a protein that suppresses the special ability of muscle stem cells to build new muscles, according to work from a team of current and former Carnegie biologists led by Chen-Ming Fan and published in Nature Metabolism.

30 Sep 2019

Physical activity may help fight depression in seniors

The benefits of exercise are widely known but kinesiologists at McMaster University have for the first time found that physical activity may help fight depression in seniors by stimulating muscle-generated mood boosters.

8 Feb 2019

NIH-funded tissue chips that model aspects of the human immune system sent to space

When traveling in space, astronauts experience physiological changes normally associated with aging, such as bone loss, muscle deterioration and altered immune systems. When the astronauts return to Earth, the changes often reverse.

5 Dec 2018

Researchers discover biomarker for most common type of heart failure

A team led by a Cedars-Sinai physician-scientist has discovered a biomarker--a protein found in the blood--for the most common type of heart failure, a new study published today in JAMA Cardiology shows.

1 Nov 2018

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Once funding is obtained, researchers can perform a clinical trial to test the efficacy of transplanting bone marrow cells into muscles to stop deterioration caused by the illness. The method has already yielded positive results on mice.

16 Mar 2018

Muscle genetics plays crucial role in success of marathon runners, study shows

For a few years, running has been fashionable. But there is a great difference between the physical demands of running a few kilometres and doing a marathon. Now Spanish researchers have concluded that genetics plays an essential role in success when completing this long distance.

6 Apr 2017

FDA approves new treatment for wide range of patients with Duchenne muscular dystrophy

The U.S. Food and Drug Administration today approved Emflaza (deflazacort) tablets and oral suspension to treat patients age 5 years and older with Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes progressive muscle deterioration and weakness.

9 Feb 2017

Muscle Deterioration News and Research

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

Study finds early stages of sarcopenia could be counteracted with timely interventions

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

FDA approval provides targeted treatment option for patients with rare DMD mutation

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

Simple accelerometers improve diagnosis of Duchenne muscular dystrophy

Carnegie biologists discover possible therapeutic target for slow healing of aged muscles

Physical activity may help fight depression in seniors

NIH-funded tissue chips that model aspects of the human immune system sent to space

Researchers discover biomarker for most common type of heart failure

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Muscle genetics plays crucial role in success of marathon runners, study shows

FDA approves new treatment for wide range of patients with Duchenne muscular dystrophy

Researchers provide insights into effects of microgravity on bone tissue

Improving muscle health could enhance response to insulin in Type 1 diabetes patients

Sarepta Therapeutics wins accelerated approval from FDA for Duchenne muscular dystrophy drug

New gene therapeutic approach could save people suffering from muscle wasting disease

Researchers find link between clu and genes that cause Parkinson's disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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