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Myelin is the fatty substance that covers and protects nerves.
Stroke can cause long-term damage to blood-spinal cord barrier, study finds

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

A team of researchers at the University of South Florida investigating the short and long-term effects of ischemic stroke in a rodent model has found that stroke can cause long-term damage to the blood-spinal cord barrier (BSCB), creating a "toxic environment" in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology. [More]
PET imaging can help identify autoimmune inflammation in MS

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging. [More]
Rare DNA  alteration may increase rsk of multiple sclerosis

Rare DNA alteration may increase rsk of multiple sclerosis

Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation - a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease. [More]
New study sheds light on link between gut microbiome and the brain

New study sheds light on link between gut microbiome and the brain

Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the "gut-brain axis" for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract. [More]
Fasting-mimicking diet may help decrease multiple sclerosis symptoms

Fasting-mimicking diet may help decrease multiple sclerosis symptoms

Evidence is mounting that a diet mimicking the effects of fasting has health benefits beyond weight loss, with a new USC-led study indicating that it may reduce symptoms of multiple sclerosis. [More]
Technical advances in neuroimaging offer new promise to clinicians

Technical advances in neuroimaging offer new promise to clinicians

The current special issue of Technology and Innovation, Journal of the National Academy of Inventors, Volume 18, Number 1 (all open access), is devoted to the evolution of neuroimaging technology, with seven articles chronicling the latest advances in this critical area. [More]
Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

A new study shows that repeated radiation therapy used to target tumors in the brain may not be as safe to healthy brain cells as previously assumed. [More]
Scientists use non-invasive way to track rapid myelination of nerve fibers in children's brains

Scientists use non-invasive way to track rapid myelination of nerve fibers in children's brains

Much like electricity traveling down wires, nerve impulses in our brain travel along nerve fibers. And just as wires need insulation to function well, nerve fibers, too, rely on a kind of insulation called myelin, a fatty substance that protects them and increases the speed at which nerve impulses travel. [More]
More neurological resources needed to manage Zika virus infections

More neurological resources needed to manage Zika virus infections

WFN Zika-Info-Service: World Federation of Neurology establishes Work Group on Zika virus to support international efforts - Lack of neurological resources in countries most concerned by the virus. [More]
Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

To me the most exciting aspect of pre-clinical imaging is its broad range, from very basic science up to applied science. You deal with a range of disciplines including biology, chemistry, physics, biochemistry, biophysics, cell biology and of course medicine, as the aim is the translation of research to humans. [More]
Bacteria-derived gut metabolites can affect brain’s myelin content and induce depression-like symptoms

Bacteria-derived gut metabolites can affect brain’s myelin content and induce depression-like symptoms

Specific combinations of gut bacteria produce substances that affect myelin content and cause social avoidance behaviors in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal eLife. This research suggests that targeting intestinal bacteria, or their metabolites, could be one way to treat debilitating psychiatric disorders and demyelinating diseases, like multiple sclerosis. [More]
Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans. [More]
Innate Immunotherapeutics announces clinical trial fully enrolled and receives strong interest from potential Pharma partners

Innate Immunotherapeutics announces clinical trial fully enrolled and receives strong interest from potential Pharma partners

Innate Immunotherapeutics Limited has closed enrolment into the Company's Phase 2B placebo controlled efficacy trial of MIS416 in patients with secondary progressive multiple sclerosis (SPMS). The study has exceeded the original recruitment target of 90 subjects with the successful enrolment this week of the 93rd patient. [More]
Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

A common antihistamine used to treat symptoms of allergies and the common cold, called clemastine fumarate, partially reversed damage to the visual system in people with multiple sclerosis (MS) in a preliminary study released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016. [More]
Zika virus may be linked to autoimmune disorder that attacks the brain's myelin

Zika virus may be linked to autoimmune disorder that attacks the brain's myelin

The Zika virus may be associated with an autoimmune disorder that attacks the brain's myelin similar to multiple sclerosis, according to a small study that is being released today and will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016. [More]
Oral administration of cyclotide may improve symptoms of multiple sclerosis

Oral administration of cyclotide may improve symptoms of multiple sclerosis

MedUni Vienna has made a crucial development in the treatment of Multiple Sclerosis (MS): Together with his team and the research group led by Gernot Schabbauer, international partners from Australia, Germany and Sweden, Christian Gruber, Chief Researcher at the Center for Physiology and Pharmacology has demonstrated in an animal model that, following treatment with a specially synthesized plant peptide (cyclotide), there is no further progression of the usual clinical signs of multiple sclerosis. [More]
Penn neurologists uncover new genetic cause of Charcot-Marie-Tooth Disease

Penn neurologists uncover new genetic cause of Charcot-Marie-Tooth Disease

Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small set of causative genes. [More]
Taste deficits appear to be more prevalent in MS patients

Taste deficits appear to be more prevalent in MS patients

Taste deficits appear to be more prevalent among multiple sclerosis (MS) patients than previously reported and correlate with brain lesions left by the debilitating disease, a new study from the University of Pennsylvania's Smell and Taste Center and the department of Radiology found. [More]
Low-oxygen exposure shortly after birth may increase learning and behavioral disorder risks

Low-oxygen exposure shortly after birth may increase learning and behavioral disorder risks

New research published in the Journal of Leukocyte Biology, shows that the development of white matter in the mouse brains is delayed when they are exposed to chronic low oxygen levels shortly after birth. [More]
Novoron Bioscience receives NIH grant to study novel therapeutic approach for multiple sclerosis

Novoron Bioscience receives NIH grant to study novel therapeutic approach for multiple sclerosis

Novoron Bioscience, Inc., a private biotech company dedicated to developing new therapeutics for disorders of the central nervous system, today announced that the company has been awarded a National Institutes of Health grant under the Small Business Innovation Research (SBIR) Program. [More]
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