Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism -; the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Sotagliflozin provides kidney and heart benefits in patients with diabetes and chronic kidney disease

Sodium-glucose cotransporter-2 (SGLT2) inhibitors, which are medications that lower blood sugar levels among other effects, provide kidney- and heart-related benefits to patients with and without diabetes.

3 Nov 2023

New atlas of fetal kidney reveals cell trajectories and disease signatures

Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

3 Nov 2023

Albuminuria associated with subclinical coronary artery pathology in type 2 diabetes

Advances in non-invasive imaging have allowed clinicians to assess both the structure and function of coronary arteries.

3 Nov 2023

High-impact clinical trial results to be presented at ASN Kidney Week 2023

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2023 November 1–November 5.

3 Nov 2023

Modifying the gut microbiota can ameliorate hypertensive kidney damage and inflammation

New research in rodents indicates that altering gut microbes may affect the development of organ damage associated with hypertension.

2 Nov 2023

Study highlights safety concerns of SGLT2i in patients with diabetes and cancer

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have heart- and kidney-related benefits for patients with and without diabetes that go beyond their initial indication for lowering blood sugar levels.

2 Nov 2023

New automated tool improves kidney disease screening in type 2 diabetes

Investigators have implemented an automated health maintenance tool created by the National Kidney Foundation into electronic medical records to prompt primary care physicians to screen for chronic kidney disease (CKD) in adult patients with type 2 diabetes.

2 Nov 2023

Higher participation in Specific Health Checkups associated with lower prevalence of kidney disease

A new Japanese ecological study revealed that prefecture-specific participation rates for Specific Health Checkups (SHC participation rates) had significant negative effects on prefecture-specific standardized incidence rates (SIRs) of treated ESKD and prefecture-specific prevalence of chronic kidney disease (CKD).

18 Oct 2023

Hackensack University Medical Center establishes new Center for Weight Loss and Metabolic Health

Hackensack University Medical Center has established the Center for Weight Loss and Metabolic Health, an integrated program to help people who have struggled to lose weight to achieve and maintain their weight loss goals.

13 Oct 2023

Study discovers protective genetic mutation for kidney disease

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt University Medical Center (VUMC) researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.

6 Oct 2023

Acute kidney injury patients on dialysis may be overtreated

Patients with acute kidney injury requiring outpatient dialysis after hospital discharge receive the same care as those with the more common end-stage kidney disease, according to a study led by UC San Francisco.

28 Sep 2023

Loss of abdominal fat may be key to reversing prediabetes

Prediabetes is a condition that precedes type 2 diabetes and increases the risk of heart attack, kidney and eye disease, and several types of cancer. Currently, there is no approved drug therapy for prediabetes available.

27 Sep 2023

Study finds risk factors linked to lower flu vaccine uptake in people with kidney disease

Among adults with chronic kidney disease (CKD) enrolled in the Chronic Renal Insufficiency Cohort (CRIC), young age, Black race, and low levels of education and income were associated with lower likelihood of getting an annual flu shot.

19 Sep 2023

Researchers develop first electronic device for continuously monitoring health of transplanted organs

Northwestern University researchers have developed the first electronic device for continuously monitoring the health of transplanted organs in real time.

8 Sep 2023

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation.

24 Aug 2023

Virtual reality-based exercises found to reduce depression and anxiety among individuals treated with hemodialysis

Researchers determined the association between regular physical exercise based on virtual reality (VR) and the development of depression.

3 Aug 2023

New kidney tissue atlas could advance understanding of kidney injury and disease

Researchers at Washington University School of Medicine in St. Louis helped lead a major study, funded by the National Institutes of Health (NIH), that uncovered rich cellular and molecular diversity in healthy and diseased kidneys, creating a kidney tissue atlas that will help further understanding of kidney injury and disease.

19 Jul 2023

‘It was a bloodbath’: Rare dialysis complication can kill, and more could be done to stop it

Nieltje Gedney was half-asleep in her West Virginia home, watching murder mysteries over the hum of a bedside hemodialysis machine, when she felt something warm and wet in her armpit.

7 Jul 2023

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

In a study led by Johns Hopkins Medicine, in collaboration with Yale School of Medicine, researchers have identified a biomarker found via a simple urine test that can be used to diagnose acute tubulointerstitial nephritis (AIN), a medical condition that causes inflammation of the kidneys and can lead to acute kidney injury (AKI) — a sudden loss of kidney function.

5 Jul 2023

Nephrology News and Research

Further Reading

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Sotagliflozin provides kidney and heart benefits in patients with diabetes and chronic kidney disease

New atlas of fetal kidney reveals cell trajectories and disease signatures

Albuminuria associated with subclinical coronary artery pathology in type 2 diabetes

High-impact clinical trial results to be presented at ASN Kidney Week 2023

Modifying the gut microbiota can ameliorate hypertensive kidney damage and inflammation

Study highlights safety concerns of SGLT2i in patients with diabetes and cancer

New automated tool improves kidney disease screening in type 2 diabetes

Higher participation in Specific Health Checkups associated with lower prevalence of kidney disease

Hackensack University Medical Center establishes new Center for Weight Loss and Metabolic Health

Study discovers protective genetic mutation for kidney disease

Acute kidney injury patients on dialysis may be overtreated

Loss of abdominal fat may be key to reversing prediabetes

Study finds risk factors linked to lower flu vaccine uptake in people with kidney disease

Researchers develop first electronic device for continuously monitoring health of transplanted organs

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Virtual reality-based exercises found to reduce depression and anxiety among individuals treated with hemodialysis

New kidney tissue atlas could advance understanding of kidney injury and disease

‘It was a bloodbath’: Rare dialysis complication can kill, and more could be done to stop it

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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