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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.
Combined public health intervention could help manage CKD in developing countries

Combined public health intervention could help manage CKD in developing countries

A simple and inexpensive public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan. The intervention, which is described in a study in the Clinical Journal of the American Society of Nephrology, will be especially helpful for protecting the kidney health of people living in developing countries. [More]
Potential marker of disease activity identified for eosinophilic esophagitis

Potential marker of disease activity identified for eosinophilic esophagitis

Researchers have identified a potential marker of disease activity for a severe and often painful food allergic disease called eosinophilic esophagitis (EoE) - possibly sparing children with EoE the discomfort and risk of endoscopic procedures to assess whether their disease is active. [More]
Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

The motor protein Myo1c binds to Neph1, a protein crucial for ensuring effective filtration by the kidney, and serves as one mode of its cellular transport, according to findings by investigators at the Medical University of South Carolina and their collaborators reported in the May 16, 2016 issue of Molecular and Cellular Biology. [More]
'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

Investigators have uncovered a "weekend effect" contributing to the worsening availability of donor kidneys in the United States. They found that kidneys that would normally be made available for transplantation were less likely to be procured from donors over the weekend (89.5% on the weekend vs. 90.2% during the week). [More]
Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas. [More]
Climate change may be key factor for increasing rates of chronic kidney disease

Climate change may be key factor for increasing rates of chronic kidney disease

Climate change may be accelerating rates of chronic kidney disease caused by dehydration and heat stress, according to research appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology. [More]
Fish oil supplements combined with anti-cancer therapy can reduce renal cell carcinoma

Fish oil supplements combined with anti-cancer therapy can reduce renal cell carcinoma

Researchers at UC Davis have shown that docosahexaenoic acid (DHA), a fatty acid commonly found in fish and fish oil supplements, reduces renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib. The study was published in the journal Molecular Cancer Therapeutics. [More]
Female hormones may be responsible for decreased risk of kidney failure in women than men

Female hormones may be responsible for decreased risk of kidney failure in women than men

Female hormones may play a role in women's decreased risk of developing kidney failure relative to men, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings may be helpful for future attempts at safeguarding women's and men's kidney health in sex-specific ways. [More]
More cautious blood pressure-lowering strategy may be reasonable for elderly CKD patients

More cautious blood pressure-lowering strategy may be reasonable for elderly CKD patients

New research indicates that higher systolic blood pressure is linked with poor outcomes in patients with kidney disease, although the association diminishes with advanced age. The findings, which come from a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), provide valuable information concerning patients who are often excluded from blood pressure-lowering clinical trials. [More]
Scientists develop new drug for life-threatening lung disease treatment

Scientists develop new drug for life-threatening lung disease treatment

Researchers are developing a new drug to treat life-threatening lung damage and breathing problems in people with severe infections like pneumonia, those undergoing certain cancer treatments and premature infants with underdeveloped, injury prone lungs. [More]
Scientists identify underlying cause of immune suppression in people with high level spinal cord injuries

Scientists identify underlying cause of immune suppression in people with high level spinal cord injuries

Scientists report in Nature Neuroscience they have identified an underlying cause of dangerous immune suppression in people with high level spinal cord injuries and they propose a possible treatment. [More]
Kidney possesses circadian clock that regulates, coordinates variety of organ's functions

Kidney possesses circadian clock that regulates, coordinates variety of organ's functions

An internal clock within the kidneys plays an important role in maintaining balance within the body, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. [More]
HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant. [More]
Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

A novel mouse model of a highly lethal form of acute myeloid leukemia (AML) offers a new tool for scientists working to better understand this disease and research new therapeutic targets. [More]
New thematic issue highlights link between hyperuricemia, gout and kidney disease

New thematic issue highlights link between hyperuricemia, gout and kidney disease

The increasing prevalence of both gout and chronic kidney disease has led to a growing interest in the association between hyperuricemia (an abnormally high level of uric acid in the blood) and kidney disease. [More]
Children with cardiomyopathy may benefit from family-linked treatment

Children with cardiomyopathy may benefit from family-linked treatment

A newly published national study by the Children's Hospital of Michigan and Wayne State University School of Medicine researchers shows that "parental impact and family functioning" become increasingly abnormal when children with cardiomyopathy-related chronic heart disease are more severely ill than children less affected by the disease. [More]
Manipulation of NAD could lead to potential therapy for acute kidney injury

Manipulation of NAD could lead to potential therapy for acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood. [More]
Study: Conservative care could be a reasonable choice for selected kidney failure patients

Study: Conservative care could be a reasonable choice for selected kidney failure patients

A new study found no significant survival advantage among elderly kidney failure patients who chose dialysis over conservative management. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology, indicate that conservative care may be a reasonable choice for selected older patients. [More]
Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Building upon earlier research, investigators at UT Southwestern Medical Center and their collaborators have identified a new innate immunity pathway that protects mammals from viral oncogenesis, the process by which viruses cause normal cells to become cancerous. [More]
EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

On World Kidney Day, leading experts from the European ADPKD Forum today issue a collaborative letter to over 350 European decision makers (European Parliament, European Commission, Council representatives) celebrating the year one progress of the Brussels Declaration on ADPKD, while calling for urgent backing from policy makers to reduce the widespread inequalities and variations in care that remain. [More]
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