Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Exeter scientists discover how two cell organelles interact at molecular level

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

20 Jan 2017

Selonterra publishes article on novel APOE4 mechanism linked to Alzheimer’s disease

Selonterra LLC, a biotechnology company discovering therapies for Alzheimer’s disease and Parkinson’s disease announced the publication of the article “Identification of a Nuclear Respiratory Factor 1 Recognition Motif in the Apolipoprotein E Variant APOE4 linked to Alzheimer’s Disease” in Scientific Reports, a peer-reviewed journal of the Nature Publishing Group.

19 Jan 2017

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

New research has found concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline in people who are at genetic risk for the condition.

12 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Protein aggregation may trigger inflammatory response linked to neurodegenerative diseases

A recent review article published online in The FASEB Journal points to the "trigger" for the inflammatory response, caused by the immune system, that precedes Alzheimer's disease and other neurological conditions.

11 Jan 2017

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

Our ability to memorize our first kiss or the last day at school as most other functions of the brain relies on communication between nerve cells at special contacts called synapses, where chemical signals are conveyed from one nerve cells to the next.

6 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

A new Tel Aviv University study finds that a popular food supplement called phosphatidylserine may be instrumental in reversing the detrimental effects of Familial Dysautonomia (FD), a debilitating neurodegenerative disorder that affects approximately 1 in 31 Jewish people of Eastern European, or Ashkenazi, ancestry.

21 Dec 2016

Scientists identify potential drug treatment in fight against Alzheimer’s disease

An international team of scientists has announced a new advance in the fight against Alzheimer’s disease by identifying a new drug target for not only improving symptoms of brain degeneration – but also to extend the life-span of the terminally ill mice.

21 Dec 2016

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease.

21 Dec 2016

Landmark clinical trial to test third investigational drug for Alzheimer's disease

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer's disease.

20 Dec 2016

Research into common congenital brain defect identifies molecular basis

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have discovered a molecular cause of hydrocephalus, a common, potentially life-threatening birth defect in which the head is enlarged due to excess fluid surrounding the brain.

14 Dec 2016

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

In a new study published online today in the journal Neurology, a research team led by neurologists at Beth Israel Deaconess Medical Center and neuropsychologists at Boston University has shown that when patients with Parkinson's disease experience a drop in blood pressure upon standing up - a condition known as orthostatic hypotension (OH) - they exhibit significant cognitive deficits.

30 Nov 2016

Researchers uncover neural progenitors in protective membranes covering the brain

In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges.

24 Nov 2016

TMDU researchers identify novel type of cell death in Huntington's disease

In Huntington's disease (HD), the huntingtin gene is mutated, causing progressive neuronal death.

22 Nov 2016

Researchers develop new mouse model to study Zika virus and find potential treatments

Researchers have developed a new mouse model that could be used in Zika research to better understand the virus and find new treatments, according to a study published in PLOS Pathogens.

18 Nov 2016

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain.

18 Nov 2016

Testing ability to recognize, remember odors may help identify people at risk for Alzheimer's disease

A non-invasive protocol testing the ability to recognize, remember and distinguish between odors was able to identify older individuals who - according to genetic, imaging and more detailed memory tests - were at increased risk of Alzheimer's disease.

15 Nov 2016

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists at the University of Sussex, trying to uncover how the common Epstein-Barr virus causes blood cancer in adults and children, have discovered how the virus takes control of two genes involved in cancer development so it can switch them on or off.

10 Nov 2016

Neurodegeneration News and Research

Further Reading

Exeter scientists discover how two cell organelles interact at molecular level

Selonterra publishes article on novel APOE4 mechanism linked to Alzheimer’s disease

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

Could pathogen infection really lead to Alzheimer’s?

Protein aggregation may trigger inflammatory response linked to neurodegenerative diseases

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

How does the brain control appetite?

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

Scientists identify potential drug treatment in fight against Alzheimer’s disease

Scientists detail structure of molecule implicated in Alzheimer's disease

Landmark clinical trial to test third investigational drug for Alzheimer's disease

Research into common congenital brain defect identifies molecular basis

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

Researchers uncover neural progenitors in protective membranes covering the brain

TMDU researchers identify novel type of cell death in Huntington's disease

Researchers develop new mouse model to study Zika virus and find potential treatments

Study finds way to detect early signs of AD by looking at retina of patients' eyes

Testing ability to recognize, remember odors may help identify people at risk for Alzheimer's disease

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Aneuro: A Year of Neuroscience in Review eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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