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Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD). [More]
Symptom trends may help predict recovery of patients suffering from post-concussion syndrome

Symptom trends may help predict recovery of patients suffering from post-concussion syndrome

Researchers at the Krembil Neuroscience Centre's Canadian Concussion Centre have identified symptom trends that may not only help predict how soon patients suffering from post-concussion syndrome (PCS) will recover, but also provide insight on how to treat those who experience persistent concussion symptoms. [More]
HD is myopathy as well as neurodegenerative disease, study suggests

HD is myopathy as well as neurodegenerative disease, study suggests

Researchers have discovered that mice with Huntington's disease (HD) suffer defects in muscle maturation that may explain some symptoms of the disorder. [More]
Johns Hopkins researchers find evidence of brain injury in young NFL players

Johns Hopkins researchers find evidence of brain injury in young NFL players

In a small study of young or recently retired NFL players, researchers at Johns Hopkins report finding evidence of brain injury and repair that is visible on imaging from the players compared to a control group of men without a history of concussion. [More]
Study finds way to detect early signs of AD by looking at retina of patients' eyes

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain. [More]
Research reveals mechanism behind progression of neurodegenerative diseases in the brain

Research reveals mechanism behind progression of neurodegenerative diseases in the brain

Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. This allows neurodegenerative diseases such as Alzheimer's to spread through the brain. [More]
Research reveals new molecular mechanisms of Huntington's disease

Research reveals new molecular mechanisms of Huntington's disease

The research just published by a group of scientists from the Centre for Genomic Regulation (CRG) in Barcelona, Spain, led by Eulàlia Martí, in cooperation with researchers from the University of Barcelona (UB) and August Pi i Sunyer Biomedical Research Institute (IDIBAPS), has brought to light new information on the molecular mechanisms that cause Huntington’s disease, and defines new pathways to therapy discovery. [More]
Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Amyotrophic lateral sclerosis (ALS) is an adult onset, fetal neurodegenerative disease that selectively affects motor neurons. [More]
Scientists investigate role of mitochondria in Alzheimer's disease pathology

Scientists investigate role of mitochondria in Alzheimer's disease pathology

On Nov. 25, 1901, a 51-year-old woman is admitted to a hospital in Frankfurt, Germany, displaying a bizarre constellation of symptoms. [More]
Virtual reality plus treadmill training may help reduce falls linked to aging, Parkinson's disease

Virtual reality plus treadmill training may help reduce falls linked to aging, Parkinson's disease

A combination of virtual reality and treadmill training may prove effective in preventing dangerous falls associated with aging, Parkinson's disease, mild cognitive impairment or dementia, according to a new Tel Aviv University-Tel Aviv Sourasky Medical Center study published in The Lancet. [More]
Distinct structures of tau protein aggregates may help determine type of dementia, study shows

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

The distinct structures of toxic protein aggregates that form in degenerating brains determine which type of dementia will occur, which regions of brain will be affected, and how quickly the disease will spread, according to a study from the Peter O'Donnell Jr. Brain Institute. [More]
Ionizing radiation may be confounding factor in Alzheimer's disease, study suggests

Ionizing radiation may be confounding factor in Alzheimer's disease, study suggests

More humans than ever are exposed to higher levels of ionizing radiation from medical equipment, airplanes, etc. A new study suggests that this kind of radiation may be a confounding factor in the neurodegenerative disease Alzheimer´s. [More]
Novel C. elegans worm strain could serve as tool for testing interventions against AD

Novel C. elegans worm strain could serve as tool for testing interventions against AD

Researchers from Yale-NUS College have partnered with researchers from the National University of Singapore and SingHealth Group to develop a novel Caenorhabditis elegans (C. elegans) worm strain which expresses an amyloid beta protein fragment involved in the development of human Alzheimer's Disease (AD). [More]
Researchers design small compounds with potential to correct mitochondrial dysfunction

Researchers design small compounds with potential to correct mitochondrial dysfunction

Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria. [More]
UA neuroscientists receive $10.3 million grant to find cause for heightened risk of Alzheimer's in women

UA neuroscientists receive $10.3 million grant to find cause for heightened risk of Alzheimer's in women

Why do more women than men get Alzheimer's disease? In their quest to find the answer, neuroscientist Roberta Diaz Brinton, PhD, and her collegues in the Center for Innovation in Brain Science at the University of Arizona Health Sciences, have been awarded a $10.3 million five-year Program Project Grant from the National Institute on Aging at the National Institutes of Health. [More]
URMC scientists receive award to explore new treatments for Huntington's disease

URMC scientists receive award to explore new treatments for Huntington's disease

A new award from the CHDI Foundation will advance promising research that aims to slow the progression of Huntington's disease. [More]
RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

In a study using Real-time intraoperative magnetic resonance imaging (RT-IMRI) to guide the transplantation of induced pluripotent stem cell (iPSC)-derived neurons into the brains of non-human primates modeled with Parkinson's disease, researchers found that RT-IMRI guidance not only allows for better visualization and monitoring of the procedure, but also helps cell survival. [More]
Researchers develop novel approach to reverse effects of Alzheimer's disease

Researchers develop novel approach to reverse effects of Alzheimer's disease

For the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's research. But the pace of progress in treating -- not to mention curing -- the debilitating, neurodegenerative disease has been painfully slow. [More]
BGU researchers elucidate molecular mechanism that could lead to new therapies for ALS

BGU researchers elucidate molecular mechanism that could lead to new therapies for ALS

Researchers from Ben-Gurion University of the Negev have published a new study that describes a novel molecular mechanism that could lead to the development of new therapies for Amyotrophic Lateral Sclerosis (ALS). [More]
GUMC receives FDA clearance to begin clinical study of cancer drug in patients with Alzheimer's disease

GUMC receives FDA clearance to begin clinical study of cancer drug in patients with Alzheimer's disease

Georgetown University Medical Center today announces the U.S. Food and Drug Administration has completed its review of an investigational new drug application (IND) for the use of nilotinib in a phase II clinical trial for patients with mild to moderate Alzheimer's disease. [More]
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