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MU researchers make new breakthrough in spinal muscular atrophy drug

MU researchers make new breakthrough in spinal muscular atrophy drug

According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time. [More]
Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Alzheimer's disease experts at NYU Langone Medical Center and elsewhere are reporting success in specifically harnessing a mouse's immune system to attack and remove the buildup of toxic proteins in the brain that are markers of the deadly neurodegenerative disease. [More]
Regulation of stem cells in zebrafish embryos results in surprising insights into Alzheimer's Disease

Regulation of stem cells in zebrafish embryos results in surprising insights into Alzheimer's Disease

New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. [More]
Researchers uncover role of epigenetic changes in Alzheimer's disease

Researchers uncover role of epigenetic changes in Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease. [More]
Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Neurotrope, Inc. (OTCQB: NTRP) today announced that results from a new study, entitled, "PKCe Deficits in Alzheimer's Disease Brains and Skin Fibroblasts," published in the recent edition of the peer-reviewed Journal of Alzheimer's Disease and co-authored by Tapan K. Khan, Ph.D.; Abhik Sen, Ph.D.; Jarin Hongpaisan, Ph.D.; Chol S. Lim, Ph.D.; Thomas J. Nelson, Ph.D., and; Dr. Daniel L. Alkon, each of the Blanchette Rockefeller Neurosciences Institute (BRNI), provide further indication of the role that protein kinase C epsilon (PKCe) may play in the potential treatment of Alzheimer's disease (AD). [More]

ALS Association surpasses $10 million in "Ice Bucket" donations

Today, The ALS Association announced it has surpassed $10 million in "Ice Bucket" donations. Specifically, as of Saturday, August 16, 2014, The ALS Association has received $11.4 million in donations compared to $1.7 million during the same time period last year (July 29 to August 16). [More]
Novogen receives funding support to commence studies in muscular dystrophy

Novogen receives funding support to commence studies in muscular dystrophy

The Australian biotechnology company, Novogen Limited today announced receipt of funding from the FSHD Global Research Foundation as part of the Company’s efforts to find effective treatments for a range of musculo-degenerative diseases including facioscapulohumeral dystrophy (FSHD). [More]
Nigral neuronal loss and α-synuclein pathology scrutinised in PD

Nigral neuronal loss and α-synuclein pathology scrutinised in PD

The severity of neurodegeneration and local burden of α-synuclein are closely coupled during disease progression in Parkinson’s disease, a post-mortem study has found. [More]
ALS Association awards 21 new research grants to find cure for amyotrophic lateral sclerosis

ALS Association awards 21 new research grants to find cure for amyotrophic lateral sclerosis

The ALS Association announced today that it has awarded 21 new research grants totaling nearly $3.5 million to find treatments and a cure for amyotrophic lateral sclerosis (ALS). The grants were awarded to scientists from laboratories located in nine different states in the United States as well as from the United Kingdom, France, Canada, Switzerland, Israel and Australia. [More]
Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility. [More]
Researchers take major step forward in developing real ALS treatments

Researchers take major step forward in developing real ALS treatments

A series of studies begun by Harvard Stem Cell Institute scientists eight years ago has lead to a report published today that may be a major step forward in the quest to develop real treatments for amyotrophic lateral sclerosis, ALS, or Lou Gehrig's disease. [More]
PLXNA4 gene may increase risk of developing Alzheimer's disease

PLXNA4 gene may increase risk of developing Alzheimer's disease

Researchers from Boston University School of Medicine report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer's disease (AD). The discovery of this novel genetic association may lead to new drug treatment options that target PLXNA4 specifically. [More]
Brain network measures placebo effects in Parkinson's disease patients

Brain network measures placebo effects in Parkinson's disease patients

Investigators at The Feinstein Institute for Medical Research have utilized a new image-based strategy to identify and measure placebo effects in randomized clinical trials for brain disorders. The findings are published in the August issue of The Journal of Clinical Investigation. [More]
Deadly neurodegenerative disease treated in worms gives hope for humans

Deadly neurodegenerative disease treated in worms gives hope for humans

An untreatable and deadly neurodegenerative disease has been modelled and treated in worms by University of Liverpool researchers, suggesting a cure could be found for humans. [More]
Sleep problems in PD patients can worsen in later stages of disease

Sleep problems in PD patients can worsen in later stages of disease

Up to 70% of Parkinson's disease (PD) patients experience sleep problems that negatively impact their quality of life. [More]
Cinnamon can be used to halt disease progression in Parkinson's patients

Cinnamon can be used to halt disease progression in Parkinson's patients

Neurological scientists at Rush University Medical Center have found that using cinnamon, a common food spice and flavoring material, can reverse the biomechanical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease (PD). [More]
Amyotrophic lateral sclerosis in veterans: an interview with Milan Michael Karol, The Robert Packard Center for ALS Research at Johns Hopkins

Amyotrophic lateral sclerosis in veterans: an interview with Milan Michael Karol, The Robert Packard Center for ALS Research at Johns Hopkins

ALS stands for Amyotrophic Lateral Sclerosis, better known as “Lou Gehrig’s Disease”. It is a progressive neurodegenerative disease characterized by the death of motor neurons in the brain and spinal cord. [More]
Increasing clearance of ALS misfolded protein from neurons improves their survival

Increasing clearance of ALS misfolded protein from neurons improves their survival

In work supported by The ALS Association, researchers have shown that increasing the clearance of misfolded protein from neurons improves their survival. The study was published today in the journal Nature Chemical Biology. [More]

American Pain Society, Pain Research Forum provide grant support for PRF's "Papers of the Week"

The American Pain Society announced today it has begun a collaboration with the Pain Research Forum in which APS will provide grant support for PRF's "Papers of the Week" website postings of new papers in pain research, which are published in peer-reviewed journals covering pain, neuroscience and related disciplines. [More]
REM sleep disorder: A sign of impending neurodegenerative disease

REM sleep disorder: A sign of impending neurodegenerative disease

How many millions of people suffer from sleep disturbance? One sleep disorder in particular, called REM behavior disorder, could be a sign of impending neurodegenerative disease, including Parkinson's and dementia, say scientists presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting. [More]