Neurodegenerative Diseases News and Research

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Key synaptic proteins could be targets for early interventions in patients with dementias

One of the most intriguing properties of the brain is its means to undergo synaptic plasticity which represents the basis for learning and memory, abilities that severely decline in the case of a dementia.

9 Jan 2018

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Neurodegeneration in ALS/FTD may be caused by TDP-43 aggregation in the cytoplasm, causing cellular traffic jams. The trial drug can sequester TDP-43.

9 Jan 2018

New understanding of how molecules regulate enzyme could lead to potential cancer targets

New understandings of how molecules affect the activity of an enzyme could lead to potential targets for the treatment of cancers and neurodegenerative diseases.

5 Jan 2018

Researchers find more precise, neuroprotective approach to fix MS-damaged nerves

Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases.

26 Dec 2017

UW study finds how tightly bound protein complexes are broken apart to become inactivated

A new study by University of Wisconsin-Madison researchers identified the structural basis for how tightly bound protein complexes are broken apart to become inactivated.

22 Dec 2017

FDA-approved drug to treat high blood pressure increases life span in worms

UT Southwestern Medical Center researchers find that an FDA-approved drug to treat high blood pressure seems to extend lifespan in worms via a cell signaling pathway that may mimic caloric restriction.

21 Dec 2017

Two studies show how cells adapt to stressors by reprogramming internal signaling networks

In a pair of publications, researchers have shown how cells adapt to stressors--like water loss--by reprogramming their internal signaling networks.

20 Dec 2017

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells.

12 Dec 2017

Research brings scientists one step closer to understanding development of ALS

University of Michigan-led research brings scientists one step closer to understanding the development of neurodegenerative disorders such as ALS.

8 Dec 2017

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health.

7 Dec 2017

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

Laser techniques could help revolutionize understanding of neurodegenerative diseases

Boulder researchers are embarking on a new project to study the progression of neurodegenerative diseases like Alzheimer's by using a new technique to measure neurons firing deep inside animal brains.

1 Dec 2017

Postnova’s AF2000 FFF system used to unlock mystery of neurodegenerative diseases

Postnova Analytics reports that the Department of Molecular Biology & Biotechnology at the University of Sheffield is using their AF2000 Field Flow Fractionation system to investigate the mechanism of amyloid formation, a protein mis-folding process implicated to be the cause of Alzheimer’s and other neurodegenerative diseases.

From Postnova Analytics 1 Dec 2017

Nanowires could be potential drug delivery tools for neurodegenerative diseases

Millions of Americans suffer from neurodegenerative diseases such as Alzheimer's and Parkinson's. Researchers have identified promising new treatments, such as cerebrolysin, but current clinical approaches are ineffective because critical concentrations of the drug dissipate within the body before reaching the blood-brain barrier and central nervous system.

15 Nov 2017

Study points at lysosomal storage disorder genes as potential key contributors to Parkinson's

An international study has shed new light on the genetic factors associated with Parkinson's disease, pointing at a group of lysosomal storage disorder genes as potential major contributors to the onset and progression of this common neurodegenerative disorder. The study appears in the journal Brain.

14 Nov 2017

Researchers shed light on link between cholera outbreaks affecting African and American continents

Researchers at the Institut Pasteur and the Wellcome Trust Sanger Institute, in collaboration with several other international institutions, recently published two studies tracing the history of cholera outbreaks in Africa, Latin America and the Caribbean from the last 60 years.

13 Nov 2017

Researchers find efficient way to produce neurons from pluripotent stem cells

Since their discovery in 2006, induced pluripotent stem cells are a glimmer of hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity revealed unexpected difficulties.

13 Nov 2017

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and death of nerve cells, which leads to problems with movement or mental functioning. Examples include Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

13 Nov 2017

Mushrooms contain high amounts of antioxidants that combat aging and promote health

A researcher team from Penn State has found mushrooms to contain high levels of two antioxidants that could promote good health and also lead to anti-aging benefits. The results of the study were published in the latest issue of Food Chemistry.

9 Nov 2017

Neurodegenerative Diseases News and Research

Key synaptic proteins could be targets for early interventions in patients with dementias

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

New understanding of how molecules regulate enzyme could lead to potential cancer targets

Researchers find more precise, neuroprotective approach to fix MS-damaged nerves

UW study finds how tightly bound protein complexes are broken apart to become inactivated

FDA-approved drug to treat high blood pressure increases life span in worms

Two studies show how cells adapt to stressors by reprogramming internal signaling networks

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Research brings scientists one step closer to understanding development of ALS

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Laser techniques could help revolutionize understanding of neurodegenerative diseases

Postnova’s AF2000 FFF system used to unlock mystery of neurodegenerative diseases

Nanowires could be potential drug delivery tools for neurodegenerative diseases

Study points at lysosomal storage disorder genes as potential key contributors to Parkinson's

Researchers shed light on link between cholera outbreaks affecting African and American continents

Researchers find efficient way to produce neurons from pluripotent stem cells

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Mushrooms contain high amounts of antioxidants that combat aging and promote health

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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