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OHSU scientists identify potential target for preventing and treating Alzheimer's disease

OHSU scientists identify potential target for preventing and treating Alzheimer's disease

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer's disease. [More]
Aerobic activity offers greater preservation of brain volume, improves cognitive performance

Aerobic activity offers greater preservation of brain volume, improves cognitive performance

Using a new MRI technique, researchers found that adults with mild cognitive impairment (MCI) who exercised four times a week over a six-month period experienced an increase in brain volume in specific, or local, areas of the brain, but adults who participated in aerobic exercise experienced greater gains than those who just stretched. [More]
Recessive gene mutations could cause debilitating neurological disease in children

Recessive gene mutations could cause debilitating neurological disease in children

Researchers have linked a debilitating neurological disease in children to mutations in a gene that regulates neuronal development through control of protein movement within neuronal cells. [More]
Researchers develop new mouse model to study Zika virus and find potential treatments

Researchers develop new mouse model to study Zika virus and find potential treatments

Researchers have developed a new mouse model that could be used in Zika research to better understand the virus and find new treatments, according to a study published in PLOS Pathogens. [More]
New mouse models may open ways to develop therapies for ALS patients

New mouse models may open ways to develop therapies for ALS patients

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, fatal neurological disease that attacks the nerve cells controlling voluntary muscles. No effective treatments have been found. [More]
Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient's own stem cells showed that the therapy appears to dampen the body's neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston. [More]
New review highlights promises and challenges of nanotechnology in neuroscience

New review highlights promises and challenges of nanotechnology in neuroscience

Despite the numerous challenges associated with the application of nanotechnology in neuroscience, it promises to have a significant impact on our understanding of how the nervous system works, how it fails in disease, and the development of earlier and less-invasive diagnostic procedures so we can intervene in the pre-clinical stage of neurological disease before extensive neurological damage has taken place. [More]
New bionic hybrid neuro chip records brain cell activity at higher resolution

New bionic hybrid neuro chip records brain cell activity at higher resolution

Brain functions are controlled by millions of brain cells. However, in order to understand how the brain controls functions, such as simple reflexes or learning and memory, we must be able to record the activity of large networks and groups of neurons. [More]
Rare neurological syndromes linked to variations in ATAD3A gene

Rare neurological syndromes linked to variations in ATAD3A gene

A team of scientists from a number of institutions around the world, including Baylor College of Medicine, has discovered that rare neurological syndromes for which there was no cause can be the result of variations in the gene ATAD3A. [More]
UA neuroscientists receive $10.3 million grant to find cause for heightened risk of Alzheimer's in women

UA neuroscientists receive $10.3 million grant to find cause for heightened risk of Alzheimer's in women

Why do more women than men get Alzheimer's disease? In their quest to find the answer, neuroscientist Roberta Diaz Brinton, PhD, and her collegues in the Center for Innovation in Brain Science at the University of Arizona Health Sciences, have been awarded a $10.3 million five-year Program Project Grant from the National Institute on Aging at the National Institutes of Health. [More]
Cedars-Sinai receives FDA approval to examine safety of combination stem cell-gene therapy in ALS patients

Cedars-Sinai receives FDA approval to examine safety of combination stem cell-gene therapy in ALS patients

Cedars-Sinai regenerative medicine investigators have received approval from the U.S. Food and Drug Administration to test a combination stem cell-gene therapy they developed to stall the progression of amyotrophic lateral sclerosis, a neurological disease that causes progressive paralysis and ultimately death. [More]
Researchers discover how toxic proteins linked to neurological diseases impair membrane-less organelles

Researchers discover how toxic proteins linked to neurological diseases impair membrane-less organelles

Researchers at St. Jude Children's Research Hospital have discovered the way toxic proteins linked to the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) incapacitate membrane-less organelles inside cells. [More]
Study shows how damage to RNA-binding protein contributes to ALS

Study shows how damage to RNA-binding protein contributes to ALS

Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic material. [More]
UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

While successful treatment of HIV with antiretroviral medications leads to undetectable levels of virus in the blood, controls the disease and leads to much longer lifespans, scientists know that HIV continues to reside in tissues. [More]
BUSM researcher receives nearly $20 million grant to support dementia and AD research

BUSM researcher receives nearly $20 million grant to support dementia and AD research

Sudha Seshadri, MD, professor of neurology at Boston University School of Medicine, has been awarded three grants this year totaling nearly $20 million from the National Institute on Aging and the National Institute of Neurological Disorders and Stroke. [More]
New study unravels cause of cognitive loss in tauopathy disorders

New study unravels cause of cognitive loss in tauopathy disorders

Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. [More]
Study to examine efficacy of orally administered medication in treating stuttering

Study to examine efficacy of orally administered medication in treating stuttering

Stuttering, an interruption in the flow of speech, affects about three million Americans. It begins most often in childhood, affecting four men for every woman. A precise cause of this complex communicative disorder is not known. [More]
Researchers discover mass migration of inhibitory neurons into the brain's frontal cortex after birth

Researchers discover mass migration of inhibitory neurons into the brain's frontal cortex after birth

Researchers at UC San Francisco have discovered a previously unknown mass migration of inhibitory neurons into the brain's frontal cortex during the first few months after birth, revealing a stage of brain development that had previously gone unrecognized. [More]
Scientists find evidence of link between coronavirus and neurological disease

Scientists find evidence of link between coronavirus and neurological disease

For the first time, researchers have found proof of a direct association between strain OC 43 of the human coronavirus (HCoV) and neurological disease in humans. [More]
UEF research shows retinal changes may be detected earlier than brain changes

UEF research shows retinal changes may be detected earlier than brain changes

Diseases of the central nervous system (CNS) may manifest as pathological changes in the retina of the eye. [More]
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