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XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

An experimental anti-inflammatory drug can protect vulnerable neurons and reduce motor deficits in a rat model of Parkinson's disease, researchers at Emory University School of Medicine have shown. [More]
BU researchers find possible way to prevent Alzheimer's disease

BU researchers find possible way to prevent Alzheimer's disease

Boston University School of Medicine researchers may have found a way to delay or even prevent Alzheimer's disease (AD). They discovered that pre-treatment of neurons with the anti-aging protein Klotho can prevent neuron death in the presence of the toxic amyloid protein and glutamate. [More]
Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system. [More]
Astrocytes may be behind mental disorders, new research reveals

Astrocytes may be behind mental disorders, new research reveals

Astrocytes, the cells that make the background of the brain and support neurons, might be behind mental disorders such as depression and schizophrenia, according to new research by a Portuguese team from the ICVS at the University of Minho. [More]
Study reveals novel epilepsy pathway linked to neurodegenerative diseases

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

A recent scientific discovery showed that mutations in prickle genes cause epilepsy, which in humans is a brain disorder characterized by repeated seizures over time. However, the mechanism responsible for generating prickle-associated seizures was unknown. [More]
Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children - Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome. [More]
New study explores processes that establish connections between nerve cells in the brain

New study explores processes that establish connections between nerve cells in the brain

New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These connections, or synapses, allow nerve cells to transmit and process information involved in thinking and moving the body. [More]
Impaired inhibition of medium spiny neurons linked to depression-like behavior in juvenile WKY rats

Impaired inhibition of medium spiny neurons linked to depression-like behavior in juvenile WKY rats

Accumulating evidence suggests that the nucleus accumbens, which is involved in mechanisms of reward and addiction, plays a role in the pathogenesis of depression and in the action of antidepressants. [More]
Research leads to better understanding of neurodegenerative, neurodevelopmental diseases

Research leads to better understanding of neurodegenerative, neurodevelopmental diseases

Throughout our lives, our brains adapt to what we learn and memorise. The brain is indeed made up of complex networks of neurons and synapses that are constantly re-configured. [More]
Study illustrates how domino effect of one genetic error can contribute to hydrocephalus

Study illustrates how domino effect of one genetic error can contribute to hydrocephalus

The mysterious condition once known as "water on the brain" became just a bit less murky this week thanks to a global research group led in part by a Case Western Reserve researcher. [More]
Findings fuel idea that processes of active movement and sensory processing are connected

Findings fuel idea that processes of active movement and sensory processing are connected

A new study by researchers at the University of Oregon published today in the journal Neuron describes a brainstem circuit in mice that may help explain how active movement impacts the way the brain processes sensory information. [More]
Study reveals way to alleviate memory deficits for Alzheimer's disease patients

Study reveals way to alleviate memory deficits for Alzheimer's disease patients

A new study from the Gladstone Institutes has revealed a way to alleviate the learning and memory deficits caused by apoE4, the most important genetic risk factor for Alzheimer's disease, improving cognition to normal levels in aged mice. [More]
Research finding could provide better understanding of severe mental illness

Research finding could provide better understanding of severe mental illness

A neuroscientist at Rutgers University-Newark says the human brain operates much the same whether active or at rest - a finding that could provide a better understanding of schizophrenia, bipolar disorder and other serious mental health conditions that afflict an estimated 13.6 million Americans. [More]
New study sheds light on role of RPM-1 protein in neuron development

New study sheds light on role of RPM-1 protein in neuron development

In a new study, scientists from the Florida campus of The Scripps Research Institute have shed new light on these complex processes, showing that a particular protein plays a far more sophisticated role in neuron development than previously thought. [More]
Gene therapy can improve regenerative capacity of injured RGCs

Gene therapy can improve regenerative capacity of injured RGCs

Because the adult mammalian central nervous system has only limited intrinsic capacity to regenerate connections after injury, due to factors both intrinsic and extrinsic to the mature neuron, therapies are required to support the survival of injured neurons and to promote the long-distance regrowth of axons back to their original target structures. [More]
Dental pulp stem cells can protect retinal ganglion cells from death following injury

Dental pulp stem cells can protect retinal ganglion cells from death following injury

Researchers at the University of Birmingham, UK, led by Dr. Ben Scheven, Dr. Wendy Leadbeater and Ben Mead have discovered that stem cells isolated from the teeth, termed dental pulp stem cells (DPSC), can protect retinal ganglion cells (RGCs) from death following injury and promote regeneration of their axons along the optic nerve. [More]
MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain. [More]

Brain uses varying strategies to filter out distractions

You know the feeling? You are trying to dial a phone number from memory… you have to concentrate…. then someone starts shouting out other numbers nearby. [More]
Research finding may accelerate development of treatments for PTSD

Research finding may accelerate development of treatments for PTSD

Scientists at Yerkes National Primate Research Center, Emory University have identified a drug that appears to make memories of fearsome events less durable in mice. [More]
Novel method to measure neuron response to transcranial magnetic stimulation of the brain

Novel method to measure neuron response to transcranial magnetic stimulation of the brain

Engineers and neuroscientists at Duke University have developed a method to measure the response of an individual neuron to transcranial magnetic stimulation (TMS) of the brain. The advance will help researchers understand the underlying physiological effects of TMS -- a procedure used to treat psychiatric disorders -- and optimize its use as a therapeutic treatment. [More]