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New gene therapy shows promise in reversing chronic pain

Researchers at NYU College of Dentistry's Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings of the National Academy of Sciences.

27 Jul 2023

Pain clinic chain to pay $11.4M to settle Medicare and Medicaid fraud claims

The owner of one of California's largest chains of pain management clinics has agreed to pay nearly $11.4 million to California, Oregon, and the federal government to settle allegations of Medicare and Medicaid fraud.

26 Jul 2023

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

The ECOG-ACRIN Cancer Research Group has enrolled the first patient in a new treatment trial to evaluate the effectiveness of adding nilotinib to standard paclitaxel chemotherapy.

20 Jul 2023

UC Davis MIND Institute receives 24th consecutive year of NIH funding for FXTAS research

It's been 22 years since UC Davis MIND Institute Medical Director Randi Hagerman and her husband, researcher Paul Hagerman, discovered the neurodegenerative condition called FXTAS (fragile X-associated tremor ataxia syndrome).

19 Jul 2023

Study finds link between DHX9 gene mutations and neurodevelopmental disorders

A group of 20 patients with undiagnosed neurodevelopmental disorders ranging from severe to mild has now received a genetic diagnosis thanks to an international team of researchers at the GREGoR Research Center at Baylor College of Medicine, the Chinese University of Hong Kong, the German Mouse Clinic and collaborating institutions.

18 Jul 2023

Researchers develop first therapy of its kind to treat cisplatin-resistant prostate cancer

Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -; cisplatin.

12 Jul 2023

Routine testing may help to reduce health disparities for people with peripheral artery disease

Low-cost, routine testing may help to reduce disparities and health care costs for people with peripheral artery disease (PAD), according to a new scientific statement from the American Heart Association, published today in the Association's flagship peer-reviewed journal Circulation.

15 Jun 2023

Study: One in three people with Type 2 diabetes in Austria suddenly stop treatment

A research team led by the Complexity Science Hub Vienna and the Medical University of Vienna has analyzed the actual prevalence of Type 2 diabetes in Austria for the first time as part of a study.

7 Jun 2023

Breast cancer patients experience more severe CIPN symptoms with paclitaxel

Chemotherapy-induced peripheral neuropathy (CIPN) – nerve pain, tingling, or numbness in the hands or feet – is a common side effect of certain cancer treatments, including two drugs frequently used to treat cancer – the taxanes paclitaxel and docetaxel.

31 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Magnetic stimulation therapy can help reduce the debilitating symptoms of diabetic gastroparesis

Magnetic stimulation of a group of nerves key to how our gut and brain communicate may help correct the conversation that goes awry in painful, debilitating diabetic gastroparesis, researchers say.

16 May 2023

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

University of Arizona Health Sciences researchers are taking the foot off the brake in their quest to improve opioid therapy while decreasing its side effects.

15 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

Study shows strong association between mastication and blood glucose levels among T2D patients

If you're a health care provider treating people with Type 2 diabetes (T2D), University at Buffalo researcher Mehmet A. Eskan has this suggestion for you: check your patients' teeth.

8 May 2023

Swedish research offers insights to improve the treatment of type 2 diabetes in India

Researchers at Lund University have shown that diabetes can be divided into five subgroups, and that there are genetic differences between the four subgroups relating to type 2 diabetes.

3 May 2023

Spinal cord stimulation may help reduce chronic pain in people undergoing active cancer treatment

Researchers at Johns Hopkins University School of Medicine say they have evidence from a new study in rats that spinal cord stimulation (SCS) may be useful in reducing chronic pain in people undergoing active treatment with a common anti-cancer drug.

From Elekta 27 Apr 2023

How alcohol intake contributes to increased pain and hypersensitivity

Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms-;one driven by alcohol intake and one by alcohol withdrawal.

21 Apr 2023

U-M to launch a population-based study on Alzheimer’s disease and related dementias in India

The University of Michigan is looking to launch a population-based study on Alzheimer’s disease and related dementias in India.

21 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

Bariatric surgery may be an effective treatment for obese people at risk of diabetes, peripheral neuropathy

For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a Michigan Medicine study shows.

10 Apr 2023