Organelle News and Research

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Researchers unveil a novel strategy for identifying key proteins in organelle communication

A collaboration between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University unveils a novel strategy for identifying key proteins in organelle communication.

13 Apr 2024

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain various specialized structures - such as the nucleus, mitochondria or peroxisomes - known as "organelles''.

12 Apr 2024

Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Discovery of new organelle could improve the understanding of chronic liver diseases

Scientists have identified a new organelle in liver cells called the mitochondria-lysosome-related organelle (MLRO).

12 Mar 2024

Kobe University study identifies FAM81A as key player for synaptic function

A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation.

7 Mar 2024

Study uncovers a biological role of transmembrane protein TMEM208

A recent study conducted in the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a biological role of a specific transmembrane protein called TMEM208.

23 Feb 2024

Researchers discover protein key to toxoplasmosis pathogen multiplication

Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

16 Feb 2024

New drug kills tumor cells by triggering a deadly calcium storm

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Viruses have limited genetic material-;and few proteins-;so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.

8 Dec 2023

Scientists unravel the mystery of how cells keep glutathione levels in check

If a delivery person leaves a package on your front step without pinging you, you likely won't know it's there.

8 Nov 2023

New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

13 Oct 2023

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants' actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

12 Oct 2023

Stress-induced ribosome dysregulation may underlie depression

A group of ribosomal protein genes connects animal models of depression to human patients with major depressive disorder.

10 Oct 2023

Midbody remnant found to play role in cancer spread

Once thought to be the trash can of the cell, a little bubble of cellular stuff called the midbody remnant is actually packing working genetic material with the power to change the fate of other cells -; including turning them into cancer.

9 Oct 2023

BU professor receives grant to study endothelial cell health in cardiometabolic disease

Naomi Hamburg, MD, the Joseph A. Vita Professor of Medicine at Boston University Chobanian & Avedisian School of Medicine, has been awarded a five-year, $3.7 million grant from the National Heart, Lung and Blood Institute for her research study, "Endothelial Cell Health Across the Spectrum of Cardiometabolic Disease."

6 Oct 2023

Organelle News and Research

Researchers unveil a novel strategy for identifying key proteins in organelle communication

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Novel signaling pathway identified in lysosome damage response

Discovery of new organelle could improve the understanding of chronic liver diseases

Kobe University study identifies FAM81A as key player for synaptic function

Study uncovers a biological role of transmembrane protein TMEM208

Researchers discover protein key to toxoplasmosis pathogen multiplication

New drug kills tumor cells by triggering a deadly calcium storm

Shedding new light on the hidden organization of the cytoplasm

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Scientists unravel the mystery of how cells keep glutathione levels in check

New insights into coronavirus E channel could lead to antiviral drugs

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Stress-induced ribosome dysregulation may underlie depression

Midbody remnant found to play role in cancer spread

BU professor receives grant to study endothelial cell health in cardiometabolic disease

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Researchers find a promising drug candidate for the treatment of ALS

University of Arkansas receives $3.1 million NIH award to study pediatric mitochondrial disorders

New research offers insight about the reason mitochondrial DNA is maternally inherited

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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