Oropharyngeal Cancer News and Research

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Urine-based test developed for early detection of head and neck tumors

Researchers from the University of Michigan Health Rogel Cancer Center have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors.

16 Apr 2024

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

The University of Texas MD Anderson Cancer Center today was awarded 16 grants totaling over $25.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer screening, early detection and prevention programs, faculty recruitment, and groundbreaking cancer research across all areas of the institution.

21 Feb 2024

Patients with HPV-related head and neck cancers treated in community centers less likely to survive

Care for patients with human papillomavirus (HPV)-related squamous cell cancers of the oropharynx (an area in back of the throat) is shifting toward community cancer centers, but patients treated in this setting may be less likely to survive, according to new research by investigators from the Johns Hopkins Kimmel Cancer Center and its Head and Neck Cancer Center.

3 Jan 2024

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023

Is obesity associated with risk of head and neck cancer?

The association between obesity and head and neck cancer risk.

29 Aug 2023

Study examines the link between oropharyngeal cancer and high-risk sexual behavior

The development of head and neck cancer is increasingly linked to HPV infection, which is a sexually transmitted disease.

14 Jul 2023

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases. Fortunately, HPV-positive oropharynx cancers have an improved survival rate compared to other head and neck cancers, allowing for less intensive treatment options, especially if diagnosed at early stages.

1 Nov 2022

HPV-related cancers increase in U.S. counties with low-income, high smoking prevalence

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, finds increases in both men and women for several HPV-related cancers in low-income counties or those with high smoking rates. Increases were slower in the highest-income US counties or those with low smoking rates.

3 Mar 2022

DNA biomarker test helps predict recurrence of HPV-driven oropharyngeal cancer after treatment

A large, multi-institutional study demonstrates that a blood test to detect circulating tumor DNA can accurately predict recurrence of HPV-driven oropharyngeal cancer following treatment.

25 Feb 2022

Study reveals rising oropharyngeal cancer incidence and mortality trends in all 50 states

Oropharyngeal cancer incidence among men is continuing to rise rapidly in nearly all 50 states and among women living in states in the Midwest and Southeast regions, according to a new study by investigators at The University of Texas Health Science Center at Houston School of Public Health in JAMA Otolaryngology-Head & Neck Surgery.

16 Dec 2021

Trial positions single-dose HPV vaccination as a high impact public health intervention

In the push to eliminate cervical cancer, researchers delivered hopeful news Nov. 17 at the 34th International Papillomavirus Conference in Toronto.

20 Nov 2021

JunD promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

Oncotarget published "JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA" which reported that the effects of low and high concentrations of arecoline on the stability of tight junctions and EMT induction were studied.

3 Sep 2021

HPV16 ctDNA assay predicts treatment response in metastatic head and neck cancer

Oncotarget published "Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma" which reported that despite the rising incidence of human papillomavirus related oropharyngeal squamous cell carcinoma, treatment of metastatic disease remains palliative.

2 Aug 2021

Same-day screening and health education program seeks to reduce disparities of preventable cancers

Evidence shows that early detection and treatment of cancer can significantly improve health outcomes, however women in Mississippi, particularly in underserved populations, experience the worst health outcomes for cervical, breast, and oropharyngeal cancer.

20 Jul 2021

U-M study finds low HPV vaccination rate among young adult men in the U.S.

The COVID-19 vaccine isn't having any trouble attracting suitors. But there's another, older model that's been mostly ignored by the young men of America: the HPV vaccine.

27 Apr 2021

Reduced-dose radiotherapy with cisplatin produces good outcomes for HPV-associated oropharyngeal cancer

A combination of reduced-dose radiotherapy using intensity-modulated radiotherapy (IMRT) combined with concurrent cisplatin met the threshold for disease control and quality of life compared to the standard of care for good-risk patients with HPV-associated oropharyngeal squamous cell carcinoma on the NRG Oncology clinical trial NRG-HN002.

29 Jan 2021

Study reveals connection between oral sex and oropharyngeal cancer

A wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated head and neck cancer that can be spread through this route, a new study led by researchers at the Johns Hopkins Kimmel Cancer Center suggests.

15 Jan 2021

Study: Oral sex can increase risk of HPV-related oropharyngeal cancer

Human papillomavirus (HPV) can infect the mouth and throat to cause cancers of the oropharynx. A new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, has found that having more than 10 prior oral sex partners was associated with a 4.3-times greater likelihood of having HPV-related oropharyngeal cancer.

11 Jan 2021

Robotic surgery for oropharyngeal cancer associated with improved health outcomes

Robotic surgery for patients with early stage, oropharyngeal squamous cell cancer is associated with improved health outcomes, including better long-term survival, according to a Cedars-Sinai study published Thursday in JAMA Oncology.

20 Aug 2020

Simple saliva test detects early throat cancer

A simple saliva test developed by QUT biomedical scientists has detected early throat cancer in a person who had no symptom and no clinical signs of cancer.

12 May 2020