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New cancer panel holds promise in detection of previously undetected viral, cancer mutations

New cancer panel holds promise in detection of previously undetected viral, cancer mutations

Researchers from Sanford Health and Chronix Biomedical today announced that results from a pilot study demonstrating the utility of a new cancer panel to detect previously undetected viral and cancer mutations are to be reported in a poster presentation titled "Detection of novel HPV mutations and chromosomal number imbalance (CNI) in oropharyngeal and laryngeal cancer using next-generation sequencing (NGS)" (Abstract #6072) at the American Society of Clinical Oncology Annual Meeting (ASCO 2014) being held from May 30 through June 3, 2014 in Chicago. [More]
No increased HPV-linked oral cancer risk for long-term partners, says study

No increased HPV-linked oral cancer risk for long-term partners, says study

Partners of patients diagnosed with human papilloma virus (HPV)-positive oropharyngeal cancer (OPC) were no more likely to test positive for oral HPV infection than people in the general population, according to a study published in the April 28 online edition of the Journal of Clinical Oncology. [More]
People urged to undergo oral cancer screenings as part of Oral Cancer Awareness Month

People urged to undergo oral cancer screenings as part of Oral Cancer Awareness Month

Oral and oropharyngeal cancer (cancer of the mouth and upper throat) collectively kill nearly one person every hour of every day of the year. [More]
Transgene raises €65.5M via two-step capital increase

Transgene raises €65.5M via two-step capital increase

Transgene SA, a French biopharmaceutical company focused on discovering, developing and manufacturing targeted immunotherapies for the treatment of cancer and infectious diseases, announces that it has raised a total of €65.5 million via a two-step capital increase. [More]
Japanese mushroom extract active hexose correlated compound (AHCC) may have role in prevention HPV-related cancers

Japanese mushroom extract active hexose correlated compound (AHCC) may have role in prevention HPV-related cancers

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Researchers use "big data" analytics to predict triple-negative breast cancer and other cancers with 95% accuracy

Researchers use "big data" analytics to predict triple-negative breast cancer and other cancers with 95% accuracy

Researchers at Case Western Reserve University and colleagues used "big data" analytics to predict if a patient is suffering from aggressive triple-negative breast cancer, slower-moving cancers or non-cancerous lesions with 95 percent accuracy. [More]
Oropharyngeal cancer patients treated with CRT show decrease in voice and speech quality

Oropharyngeal cancer patients treated with CRT show decrease in voice and speech quality

Oropharyngeal cancer patients treated with combined chemotherapy and radiation therapy reported a decrease in their voice and speech quality (VSQ) for up to one year after the completion of treatment, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium. [More]
HPV-positive oropharyngeal cancer patients show longer survival pattern than those related to smoking

HPV-positive oropharyngeal cancer patients show longer survival pattern than those related to smoking

People with late-stage cancer at the back of the mouth or throat that recurs after chemotherapy and radiation treatment are twice as likely to be alive two years later if their cancer is caused by the human papillomavirus (HPV), new research led by a Johns Hopkins scientist suggests. [More]
Reduction of RT to IB lymph nodes may result in better salivary function in head, neck cancer patients

Reduction of RT to IB lymph nodes may result in better salivary function in head, neck cancer patients

For head and neck cancer patients undergoing radiation therapy, a reduction in the amount of radiation treatment volume to the submandibular (level IB) lymph nodes resulted in better patient-reported salivary function, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium. [More]
Study reveals alarming increase in oropharyngeal cancers among young adults

Study reveals alarming increase in oropharyngeal cancers among young adults

A new study reveals an alarming increase in oropharyngeal cancers among young adults. While the exact cause for this phenomenon is unknown, the human papillomavirus (HPV) may be to blame. [More]
Transgene welcomes SillaJen’s intention to acquire Jennerex

Transgene welcomes SillaJen’s intention to acquire Jennerex

Transgene SA (Paris:TNG) said today that it welcomed the announcement by SillaJen, Inc. of its intention to acquire Jennerex, Inc. and has consequently given its consent to the definitive merger agreement. [More]
Incidence of oropharyngeal cancer on the rise

Incidence of oropharyngeal cancer on the rise

NCI scientists report that the incidence of oropharyngeal cancer significantly increased during the period 1983-2002 among people in countries that are economically developed. [More]
Use of feeding tubes in OPC cancer patients treated with IMPT decreased by 50%

Use of feeding tubes in OPC cancer patients treated with IMPT decreased by 50%

A new study from researchers at The University of Texas MD Anderson Proton Therapy Center found that the use of feeding tubes in oropharyngeal carcinoma cancer patients treated with intensity modulated proton therapy decreased by more than 50 percent compared to patients treated with intensity modulated radiation therapy. [More]
Researchers blame HPV for increased number of young adults with oropharyngeal cancer

Researchers blame HPV for increased number of young adults with oropharyngeal cancer

The human papillomavirus (HPV) may be to blame for the alarming increase of young adults with oropharyngeal cancer, according to researchers from Henry Ford Hospital in Detroit. [More]
Study shows smokers, single men more likely to acquire cancer-causing oral HPV

Study shows smokers, single men more likely to acquire cancer-causing oral HPV

​Smokers and single men are more likely to acquire cancer-causing oral human papillomavirus (HPV), according to new results from the HPV Infection in Men (HIM) Study. Researchers from Moffitt Cancer Center, the National Cancer Institute, Mexico and Brazil also report that newly acquired oral HPV infections in healthy men are rare and when present, usually resolve within one year. [More]
HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils. [More]
Partners of HPV-related oral cancer patients have no increased prevalence of oral infections: Study

Partners of HPV-related oral cancer patients have no increased prevalence of oral infections: Study

Spouses and long-term partners of patients with mouth and throat cancers related to infection with the human papilloma virus (HPV) appear to have no increased prevalence of oral HPV infections, according to results of a multicenter, pilot study led by Johns Hopkins investigators. [More]
New clinical trial may help reduce radiation dose for patients with HPV-positive oropharyngeal cancer

New clinical trial may help reduce radiation dose for patients with HPV-positive oropharyngeal cancer

Researchers from Fox Chase Cancer Center and other institutions have completed a phase II clinical trial that may help identify those patients with HPV-positive oropharyngeal cancer who do not require the full radiation dose given in a standard regimen of Intensity-Modulated Radiation Therapy (IMRT). Preliminary findings will be presented by Shanthi Marur, first author on the study and an oncologist at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, at the 49th Annual Meeting of the American Society of Clinical Oncology on Sunday, June 2. [More]
Study finds HPV improves survival in African Americans with oropharyngeal cancer

Study finds HPV improves survival in African Americans with oropharyngeal cancer

Even though the human papillomavirus (HPV) is a risk factor for certain head and neck cancers, its presence could make all the difference in terms of survival, especially for African Americans with throat cancer, according to a newly published study from Henry Ford Hospital in Detroit. [More]
Overall cancer death rates continue to decline in the U.S.: Report

Overall cancer death rates continue to decline in the U.S.: Report

The Annual Report to the Nation on the Status of Cancer, 1975-2009, shows that overall cancer death rates continued to decline in the United States among both men and women, among all major racial and ethnic groups, and for all of the most common cancer sites, including lung, colon and rectum, female breast, and prostate. [More]