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According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.
Research unlocks potential new therapies for inflammatory diseases

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue. [More]
Active older population, better technology may be cause for more hip and knee replacement surgeries

Active older population, better technology may be cause for more hip and knee replacement surgeries

An active aging population is a good thing for society. It also keeps John Shields, M.D., very busy. [More]
Decision aid for OA helps increase rate of total knee replacement among black patients

Decision aid for OA helps increase rate of total knee replacement among black patients

A decision aid that consisted of a video that describes the risks and benefits of total knee replacement surgery significantly increased the rate of this surgery among black patients, according to a study published online by JAMA Surgery. [More]
Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis (PsA) is an inflammatory condition closely related to and most often co-occurring with psoriasis. [More]
Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

A new study shows a link between mothers with rheumatoid arthritis and children with epilepsy. [More]
HSS conducts survey to assess musculoskeletal health needs of surrounding communities

HSS conducts survey to assess musculoskeletal health needs of surrounding communities

Hospital for Special Surgery, which has an Outpatient Center in Stamford, plans to increase outreach and educational programs to meet the needs of surrounding communities. [More]
Scientists pinpoint the brain region responsible for ‘placebo effect’ in pain relief

Scientists pinpoint the brain region responsible for ‘placebo effect’ in pain relief

Scientists have identified for the first time the region in the brain responsible for the "placebo effect" in pain relief, when a fake treatment actually results in substantial reduction of pain, according to new research from Northwestern Medicine and the Rehabilitation Institute of Chicago. [More]
Researchers develop new blood test for diagnosis of early-stage osteoarthritis

Researchers develop new blood test for diagnosis of early-stage osteoarthritis

Patients could soon be diagnosed with early-stage arthritis several years before the onset of physical and irreversible symptoms, thanks to a new test developed by researchers at the University of Warwick. [More]

Prolotherapy linked to improved knee-specific symptoms in patients with osteoarthritis

Prolotherapy, an injection-based complementary treatment for symptomatic knee osteoarthritis, was associated with improved knee-specific symptoms, quality of life, and ability to participate in daily activities among the majority of individuals who participated in several small clinical studies. [More]
Swiss specialists report success of new cell-based repair technology for articular cartilage defects

Swiss specialists report success of new cell-based repair technology for articular cartilage defects

Writing in The Lancet, Swiss doctors report that cartilage cells harvested from patients’ own noses have been used to successfully produce cartilage transplants for the treatment of the knees of 10 adults (aged 18-55 years) whose cartilage was damaged by injury. [More]
Research finds no change in patient’s physical activity after hip replacement surgery

Research finds no change in patient’s physical activity after hip replacement surgery

New research from the University of East Anglia (UEA) shows that, surprisingly, patients' physical activity does not increase following hip replacement surgery. [More]
Two leading non-profit organizations sign strategic affiliation to hasten drug development

Two leading non-profit organizations sign strategic affiliation to hasten drug development

The Scripps Research Institute and the California Institute for Biomedical Research - two leading non-profit research organizations - today announced the signing of a strategic affiliation that combines the two organizations into a new biomedical research entity with the tools and know-how to rapidly translate its scientific discoveries into life-saving medicines for the public benefit. [More]
New gait analysis laboratory and equipment installed at Bournemouth University’s Orthopaedic Research Institute

New gait analysis laboratory and equipment installed at Bournemouth University’s Orthopaedic Research Institute

A new world-class orthopaedic gait analysis laboratory - the ‘GRAIL’ (gait real-time analysis interactive laboratory) - and state-of-the-art virtual reality training equipment have been installed at Bournemouth University’s Orthopaedic Research Institute thanks to a £700,000 local growth fund investment secured by Dorset Local Enterprise Partnership. [More]
U-M investigators awarded $7.5 million NIH grant to expand chronic pain research

U-M investigators awarded $7.5 million NIH grant to expand chronic pain research

In order to better understand the disparity between identifiable damage and chronic pain, the National Institutes of Health has awarded $7.5 million over five years to physician-scientists at the University of Michigan Health System. [More]
Researchers seek to shed light on link between ACL and osteoarthritis

Researchers seek to shed light on link between ACL and osteoarthritis

Every year, about 250,000 people in the U.S. sustain injuries to the anterior cruciate ligament (ACL), and about half of these individuals end up having reconstructive surgery. [More]
Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

High cholesterol might harm more than our cardiovascular systems. New research using animal models, published online in The FASEB Journal, suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis. [More]
Nanoparticle injections may help prevent cartilage degeneration in osteoarthritis patients

Nanoparticle injections may help prevent cartilage degeneration in osteoarthritis patients

Osteoarthritis is a debilitating condition that affects at least 27 million people in the United States, and at least 12 percent of osteoarthritis cases stem from earlier injuries. [More]
New NJR report highlights that patient factors can have major impact on revision of hip replacements

New NJR report highlights that patient factors can have major impact on revision of hip replacements

Younger joint replacement patients, who are likely to be more active, may put more strain on their implants and increase the risk of revision, a new report published today (Tuesday 13 September 2016) has said. [More]
X-rays can be effective diagnostic tool for screening knee pain in patients older than 40

X-rays can be effective diagnostic tool for screening knee pain in patients older than 40

Knee pain is common among Americans age 40 and up. Nearly 1 in 17 people visit doctors' offices each year for knee pain or injuries from osteoarthritis--a progressive "wear and tear" disease of the joints. [More]
Researchers discover risk factors that contribute to fracture nonunion in adults

Researchers discover risk factors that contribute to fracture nonunion in adults

Dr. Robert Zura, the Robert D'Ambrosia Professor and Head of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team that identified risk factors which may help orthopaedic surgeons better predict a serious complication of bone fractures. [More]
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