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According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.
Heptares Therapeutics, AstraZeneca report significant progress in drug discovery collaboration

Heptares Therapeutics, AstraZeneca report significant progress in drug discovery collaboration

Heptares Therapeutics, the clinical-stage GPCR structure-guided drug discovery and development company, announces significant progress in its drug discovery collaboration with AstraZeneca. [More]
QMUL researchers develop new 'microcapsule' method to treat osteoarthritis

QMUL researchers develop new 'microcapsule' method to treat osteoarthritis

A new 'microcapsule' treatment delivery method developed by researchers at Queen Mary University of London could reduce inflammation in cartilage affected by osteoarthritis and reverse damage to tissue. The research was funded by Arthritis Research UK and the AO Foundation. [More]
Study finds early symptoms of knee osteoarthritis in people who use stairs

Study finds early symptoms of knee osteoarthritis in people who use stairs

People who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new study by University of Leeds experts. [More]
CUMC researchers identify that OCR stem cells can regenerate bone and cartilage in mice

CUMC researchers identify that OCR stem cells can regenerate bone and cartilage in mice

A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice. The discovery by researchers at Columbia University Medical Center is reported today in the online issue of the journal Cell. [More]
Novastem uses Stemedica's stem cell products to treat patient in ischemic stroke study

Novastem uses Stemedica's stem cell products to treat patient in ischemic stroke study

Novastem, a leader in regenerative medicine, announces the treatment of its first patient in its study for ischemic stroke at Clinica Santa Clarita. [More]
Injection technique provides pain relief following knee replacement surgery

Injection technique provides pain relief following knee replacement surgery

It's estimated that more than half of adults in the United States diagnosed with knee osteoarthritis will undergo knee replacement surgery. [More]
Older adults participating in hospital-based exercise program report less pain, stiffness and fatigue

Older adults participating in hospital-based exercise program report less pain, stiffness and fatigue

It may seem counterintuitive, but exercise can be beneficial for people suffering from arthritis and other muscle and joint conditions. A new study at Hospital for Special Surgery finds that older adults experienced less pain, reduced stiffness and less fatigue after participating in a hospital-based exercise program. [More]
Mylan announces U.S. launch of Celecoxib Capsules

Mylan announces U.S. launch of Celecoxib Capsules

Mylan Inc. today announced the U.S. launch of its Celecoxib Capsules, 50 mg, 100 mg, 200 mg, and 400 mg, one of the first available generic versions of Pfizer's Celebrex Capsules, which is indicated for the relief of the signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute pain in adults. [More]
Meniscal surgery may increase risk of osteoarthritis, cartilage loss

Meniscal surgery may increase risk of osteoarthritis, cartilage loss

A popular surgery to repair meniscal tears may increase the risk of osteoarthritis and cartilage loss in some patients, according to research presented today at the annual meeting of the Radiological Society of North America. The findings show that the decision for surgery requires careful consideration in order to avoid accelerated disease onset, researchers said. [More]
Perrigo receives final FDA approval for diclofenac sodium topical solution 1.5% w/w

Perrigo receives final FDA approval for diclofenac sodium topical solution 1.5% w/w

Perrigo Company plc today announced that it has received final approval from the U.S. Food and Drug Administration on its Abbreviated New Drug Application (ANDA) for diclofenac sodium topical solution 1.5% w/w. Shipments to our pharmacy customers have commenced. [More]
Two medical research bodies announce new research centre to tackle musculoskeletal disorders

Two medical research bodies announce new research centre to tackle musculoskeletal disorders

A major new research centre to tackle the impact of musculoskeletal disorders on people's ability to work has been announced by two leading medical research bodies. [More]
Total hip replacement: An excellent option for younger patients with juvenile idiopathic arthritis

Total hip replacement: An excellent option for younger patients with juvenile idiopathic arthritis

When you think of hip replacement surgery, you generally envision an older adult with painful osteoarthritis. But the procedure is also used for younger patients with juvenile idiopathic arthritis (JIA) whose joints have been severely damaged by the disease. [More]
Health benefits of modified formulation of curcumin supplements

Health benefits of modified formulation of curcumin supplements

The health benefits of over-the-counter curcumin supplements might not get past your gut, but new research shows that a modified formulation of the spice releases its anti-inflammatory goodness throughout the body. [More]
Researchers explore why many patients opt out of bariatric surgical procedure

Researchers explore why many patients opt out of bariatric surgical procedure

Researchers from the University Health Network in Toronto are hoping to improve the operational efficiency of bariatric surgery programs to increase access to care. Studies have shown that bariatric operations can alleviate chronic health issues like diabetes and arthritis for extremely obese people. [More]
Medical illness common in bipolar disorder

Medical illness common in bipolar disorder

Patients with bipolar disorder have high rates of medical illness, which often exceeds the levels observed in patients with unipolar depression, show results of a UK-based study. [More]
Mayo Clinic orthopedic surgeon explains how scoliosis affects Baby Boomers

Mayo Clinic orthopedic surgeon explains how scoliosis affects Baby Boomers

For many adults, the word scoliosis conjures up childhood memories of lining up in gym class for an examination by the school nurse. But scoliosis isn't just a pediatric condition. Curvature of the spine can develop in adults too, and the osteoporosis that can accompany menopause is a risk factor. [More]
Calchan, Galapagos partner to discover and develop novel target for osteoarthritic pain

Calchan, Galapagos partner to discover and develop novel target for osteoarthritic pain

Calchan Holdings Limited, a UK company focused on the development of novel medicines based on calcium ion channel modulators, and Galapagos NV, a clinical stage biotech company focused on developing novel mode of action medicines, today announce that they have entered into a research collaboration in the area of osteoarthritis pain. [More]
Bone mineral density not linked to musculoskeletal pain

Bone mineral density not linked to musculoskeletal pain

Bone mineral density does not contribute to musculoskeletal pain, researchers report in findings that shed light on the controversy over whether osteoporosis is a painless disease. [More]
Acupuncture fails to hit the mark for chronic knee pain

Acupuncture fails to hit the mark for chronic knee pain

Research findings do not support the use of needle or laser acupuncture for treating chronic knee pain in patients older than 50 years. [More]
Antibiotic exposure in infancy linked to childhood obesity

Antibiotic exposure in infancy linked to childhood obesity

Repeated exposure to broad-spectrum antibiotics in the first two years of life is associated with early childhood obesity, say researchers from The Children's Hospital of Philadelphia in a retrospective study based on data from electronic health records from the extensive CHOP Care Network. [More]