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According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.
Two medical research bodies announce new research centre to tackle musculoskeletal disorders

Two medical research bodies announce new research centre to tackle musculoskeletal disorders

A major new research centre to tackle the impact of musculoskeletal disorders on people's ability to work has been announced by two leading medical research bodies. [More]
Total hip replacement: An excellent option for younger patients with juvenile idiopathic arthritis

Total hip replacement: An excellent option for younger patients with juvenile idiopathic arthritis

When you think of hip replacement surgery, you generally envision an older adult with painful osteoarthritis. But the procedure is also used for younger patients with juvenile idiopathic arthritis (JIA) whose joints have been severely damaged by the disease. [More]
Health benefits of modified formulation of curcumin supplements

Health benefits of modified formulation of curcumin supplements

The health benefits of over-the-counter curcumin supplements might not get past your gut, but new research shows that a modified formulation of the spice releases its anti-inflammatory goodness throughout the body. [More]
Researchers explore why many patients opt out of bariatric surgical procedure

Researchers explore why many patients opt out of bariatric surgical procedure

Researchers from the University Health Network in Toronto are hoping to improve the operational efficiency of bariatric surgery programs to increase access to care. Studies have shown that bariatric operations can alleviate chronic health issues like diabetes and arthritis for extremely obese people. [More]
Medical illness common in bipolar disorder

Medical illness common in bipolar disorder

Patients with bipolar disorder have high rates of medical illness, which often exceeds the levels observed in patients with unipolar depression, show results of a UK-based study. [More]
Mayo Clinic orthopedic surgeon explains how scoliosis affects Baby Boomers

Mayo Clinic orthopedic surgeon explains how scoliosis affects Baby Boomers

For many adults, the word scoliosis conjures up childhood memories of lining up in gym class for an examination by the school nurse. But scoliosis isn't just a pediatric condition. Curvature of the spine can develop in adults too, and the osteoporosis that can accompany menopause is a risk factor. [More]
Calchan, Galapagos partner to discover and develop novel target for osteoarthritic pain

Calchan, Galapagos partner to discover and develop novel target for osteoarthritic pain

Calchan Holdings Limited, a UK company focused on the development of novel medicines based on calcium ion channel modulators, and Galapagos NV, a clinical stage biotech company focused on developing novel mode of action medicines, today announce that they have entered into a research collaboration in the area of osteoarthritis pain. [More]
Bone mineral density not linked to musculoskeletal pain

Bone mineral density not linked to musculoskeletal pain

Bone mineral density does not contribute to musculoskeletal pain, researchers report in findings that shed light on the controversy over whether osteoporosis is a painless disease. [More]
Acupuncture fails to hit the mark for chronic knee pain

Acupuncture fails to hit the mark for chronic knee pain

Research findings do not support the use of needle or laser acupuncture for treating chronic knee pain in patients older than 50 years. [More]
Antibiotic exposure in infancy linked to childhood obesity

Antibiotic exposure in infancy linked to childhood obesity

Repeated exposure to broad-spectrum antibiotics in the first two years of life is associated with early childhood obesity, say researchers from The Children's Hospital of Philadelphia in a retrospective study based on data from electronic health records from the extensive CHOP Care Network. [More]
Studies explain why some people are at greater risk for ACL injury than others

Studies explain why some people are at greater risk for ACL injury than others

The successful rise and fall of an athlete's moving body relies on an orchestrated response of bones, joints, ligaments and tendons, putting the many angles and intersecting planes - literally the geometry - of a critical part like a knee joint to the test. But it's more than just a footfall error at the root of one of the most devastating of sports injuries: the ACL or anterior cruciate ligament tear. [More]

Neuropathic pain phenotype identified in knee osteoarthritis

Some patients with knee osteoarthritis may experience neuropathic-like symptoms associated with central pain processing, reflecting a discrete phenotype, study findings suggest. [More]
Fat mass contributes to musculoskeletal pain risk

Fat mass contributes to musculoskeletal pain risk

People with high fat mass could be at an increased risk of musculoskeletal pain, say researchers. [More]
MOVANTIK tablets get FDA approval for treatment of OIC in patients with chronic, non-cancer pain

MOVANTIK tablets get FDA approval for treatment of OIC in patients with chronic, non-cancer pain

Nektar Therapeutics reported today that partner AstraZeneca today announced that the US Food and Drug Administration (FDA) approved MOVANTIK (naloxegol) tablets as the first once-daily oral peripherally-acting mu-opioid receptor antagonist (PAMORA) medication for the treatment of opioid-induced constipation (OIC), in adult patients with chronic, non-cancer pain. [More]
Inadequate pain relief common in knee osteoarthritis

Inadequate pain relief common in knee osteoarthritis

Patients with knee osteoarthritis requiring analgesic therapy are often not receiving adequate pain relief, researchers report. [More]
Research for better understanding of pathology of severe form of dwarfism

Research for better understanding of pathology of severe form of dwarfism

A better understanding of the pathology of a severe form of dwarfism as well as a possible window of treatment have been discovered by researchers at The University of Texas Health Science Center at Houston (UTHealth). [More]
Around 9.6% of women diagnosed with dry eye disease, treated with artificial tear eye drops

Around 9.6% of women diagnosed with dry eye disease, treated with artificial tear eye drops

The symptoms of dry eye disease include the sensation of grit in the eye, frequently accompanied by itching, burning and visual disturbance. The causes are poorly understood. [More]
Ampio updates phase III, multicenter, double-blind STEP study of Ampion for knee osteoarthritis

Ampio updates phase III, multicenter, double-blind STEP study of Ampion for knee osteoarthritis

Ampio Pharmaceuticals, Inc. today announced an update on the phase III, multicenter, double-blind STEP study of Ampion™ for osteoarthritis of the knee. [More]
Comprehensive fitness and nutrition regimens may prevent bone and muscle deterioration

Comprehensive fitness and nutrition regimens may prevent bone and muscle deterioration

Being physically active may significantly improve musculoskeletal and overall health, and minimize or delay the effects of aging, according to a review of the latest research on senior athletes (ages 65 and up) appearing in the September issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS). [More]
Research roundup: Benefits of hip surgery; preventing surgical infections; assessing ACOs' predecessors

Research roundup: Benefits of hip surgery; preventing surgical infections; assessing ACOs' predecessors

Surgical treatment of hip fractures can achieve better survival and functional outcomes than nonoperative treatment, but less is known about its economic benefits. ... We estimated the effects of surgical treatment for displaced hip fractures through a Markov cohort analysis of patients 65 years and older. ... Estimated average lifetime societal benefits per patient exceeded the direct medical costs of hip fracture surgery by $65,000 to $68,000 for displaced hip fractures. With the exception of the assumption of nursing home use, the sensitivity analyses show that surgery produces positive net societal savings (Gu, Koenig, Mather and Tongue, 8/5). [More]