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According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.
Research findings provide new hope for people suffering from dry eye disease

Research findings provide new hope for people suffering from dry eye disease

Natural lubricants play an important role in health, including a well-known effect to help prevent osteoarthritis in knee and ankle joints. However, much is still unknown about their role and function in other areas of the body. [More]
University of Florence professor awarded ESCEO-IOF Servier Pierre D. Delmas Prize

University of Florence professor awarded ESCEO-IOF Servier Pierre D. Delmas Prize

Today, at the opening of the European Congress on Osteoporosis & Osteoarthritis in Rome, Italy, Professor Maria Luisa Brandi MD, Professor of Endocrinology and Metabolic Diseases at the University of Florence, Florence, Italy was presented with ESCEO-IOF Servier Pierre D. Delmas Prize. [More]
Running or jumping may worsen cartilage damage, MIT engineers find

Running or jumping may worsen cartilage damage, MIT engineers find

Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together. [More]

ESCEO and IOF honor Dr. Mary L. Bouxsein with ESCEO-IOF Herbert Fleisch Medal

Dr. Mary L. Bouxsein has been awarded the ESCEO-IOF Herbert Fleisch Medal in honor of her work in the field of skeletal fragility. [More]

European Congress on Osteoporosis & Osteoarthritis starts in Rome

The world's largest congress dedicated to the epidemiology, pathogenesis, prevention, and treatment of osteoporosis and osteoarthritis has opened today in Rome, Italy with 4500 delegates. [More]
Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros Corporation today announced positive data in the most commonly used model for studying the clinical and pathological features of multiple sclerosis (MS), further advancing its development program of GPR17-targeting compounds for the treatment of MS. Compounds previously discovered by Omeros that inhibit GPR17, an orphan G protein-coupled receptor (GPCR) unlocked by Omeros, significantly improved function from experimental autoimmune encephalomyelitis (EAE) in mice. [More]
Orthopaedic surgeons should recommend weight loss to patients prior to joint replacement

Orthopaedic surgeons should recommend weight loss to patients prior to joint replacement

The obesity epidemic in America and its impact on musculoskeletal health, as well as related treatment outcomes and costs, was discussed during the AAOS Now forum, "Obesity, Orthopaedics and Outcomes," at the 2013 Annual Meeting of the American Academy of Orthopaedic Surgeons at McCormick Place in Chicago. [More]

Research: Mobility shoes improve knee loading for osteoarthritis patients

New research suggests that patients with knee osteoarthritis (OA) who wear flat, flexible footwear (mobility shoes) had significant reduction in knee loading-the force placed upon the joint during daily activities. [More]
Study offers new insights into how nervous system processes hot and cold temperatures

Study offers new insights into how nervous system processes hot and cold temperatures

A study from the University of North Carolina School of Medicine offers new insights into how the nervous system processes hot and cold temperatures. The research led by neuroscientist Mark J. Zylka, PhD, associate professor of cell biology and physiology, found an interaction between the neural circuits that detect hot and cold stimuli: cold perception is enhanced when nerve circuitry for heat is inactivated. [More]
Nektar Therapeutics presents positive results for NKTR-214 at AACR Annual Meeting

Nektar Therapeutics presents positive results for NKTR-214 at AACR Annual Meeting

Nektar Therapeutics today presented positive preclinical data for NKTR-214, a novel cancer immunotherapy which targets the IL-2 receptor complex, at the 2013 American Association for Cancer Research Annual Meeting. [More]

Only 50% people with arthritis report significant improvement after hip or knee replacement

Only half of people with arthritis who had a hip or knee replacement reported a significant improvement in pain and mobility after surgery, according to a new study led by Women's College Hospital and the Institute for Clinical and Evaluative Sciences (ICES). [More]
Ampio Pharmaceuticals receives FDA IND approval to start clinical trial of Ampion

Ampio Pharmaceuticals receives FDA IND approval to start clinical trial of Ampion

Ampio Pharmaceuticals, Inc. today announced FDA acceptance of its IND and the treatment of the first fifteen (15) patients in its clinical trial using Ampion™ to treat osteoarthritis of the knee. [More]
Adding lubricin to fluid in our joints may prevent osteoarthritis, researchers find

Adding lubricin to fluid in our joints may prevent osteoarthritis, researchers find

Think new discoveries are the bee's knees? This one is even better -- this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, to the fluid in our joints may reduce the risk of or even prevent osteoarthritis. [More]

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

A new Guidance recently published by the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the International Osteoporosis Foundation (IOF) reflects the most current advances in the diagnosis and management of osteoporosis, the 'silent disease' which affects up to one in two postmenopausal women. [More]
New data shows overall effectiveness of ACL surgery

New data shows overall effectiveness of ACL surgery

Orthopaedic surgeons have debated the effectiveness of the single versus double-bundle method of anterior cruciate ligament repair for years. However new data shows both techniques lead to similarly effective outcomes for patients, according to researchers presenting their work today at the American Orthopaedic Society for Sports Medicine's Specialty Day in Chicago, IL. [More]

OATS treatment for knee defects may not allow military patients to return to full duty, say researchers

Treatment of large cartilage knee defects with an allograft osteoarticular transplant may not allow some military personnel to return to full active duty status, say researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Specialty Day in Chicago, IL. [More]

Adult stem cells improve cartilage repair

Using adult stem cells is a good way of culturing better-quality cartilage to repair worn hips and knees. New cartilage that has good properties can be grown in particular by cultivating adult stem cells in combination with a small quantity of cells from the patient's own cartilage. [More]
Ill health and retirement: an interview with Dr Sabrina Pit, University Centre for Rural Health, University of Sydney

Ill health and retirement: an interview with Dr Sabrina Pit, University Centre for Rural Health, University of Sydney

In our study population, which was drawn from NSW Australia only, the proportion of working aged men who were fully retired due to ill-health in cities is five percent, eight percent for inner regional areas and nine for outer regional areas. [More]

European Congress on Osteoporosis & Osteoarthritis to start in April

Attend the European Congress on Osteoporosis & Osteoarthritis Rome, Italy from April 17-20, 2013 and earn up to 19 European Accreditation Council for Continuing Medical Education credits. [More]
Study: Total knee replacements in younger patients with juvenile arthritis last for 10 years

Study: Total knee replacements in younger patients with juvenile arthritis last for 10 years

When you think of knee replacement surgery, you generally envision an older adult with painful arthritis. But the procedure is also used for younger patients with juvenile idiopathic arthritis whose joints have been severely damaged by the disease. Because the surgery in younger patients is relatively rare, little data exist on the longevity of knee replacements in JIA patients. [More]