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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Research suggests effective role for natural steroid hormones in treating breast cancer

Research suggests effective role for natural steroid hormones in treating breast cancer

A new study supports a growing body of research suggesting a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard anti-hormone therapies. [More]
Chemclin's Vitamin D assay helps in quantitative determination of 25-OH Vitamin D in human serum

Chemclin's Vitamin D assay helps in quantitative determination of 25-OH Vitamin D in human serum

Chemclin's new Vitamin D assay provides components for in-vitro quantitative determination of 25-Hydroxy Vitamin D (25-OH Vitamin D) in human serum by a competitive chemiluminescent assay method. [More]
Study examines mechanism of bone-protective properties of California dried plums

Study examines mechanism of bone-protective properties of California dried plums

Fifty-seven million Americans suffer from low bone density or osteoporosis, a disease which causes bones to become so weak and brittle that even a minor fall or other stresses may cause fractures. [More]

Reducing the risk of fractures in older women

Reducing the risk of fractures in older women is the aim of a research study at Griffith University. [More]
Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemopre­vention is to arrest or reverse the progression of pre­malignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells. [More]
Study: People with mobility impairments under age 65 have higher rates of smoking

Study: People with mobility impairments under age 65 have higher rates of smoking

Researchers from The Miriam Hospital have found that people with mobility impairments under age 65 have significantly higher rates of smoking than those without mobility impairments. [More]
Medical treatment guidelines for diabetes

Medical treatment guidelines for diabetes

Medical treatment guidelines are suggestions that international organizations such as the American Diabetes Association, the European Society for the Study of Diabetes and the American Association of Clinical Endocrinologists, used to set the tone in the control of the disease and how to apply a better therapy, depending on the physical condition of the person. [More]
New class of anti-arthritic drugs reduce arthritic joint inflammation and periodontitis

New class of anti-arthritic drugs reduce arthritic joint inflammation and periodontitis

Inflammatory diseases can occur simultaneously in distinct sites in the same patient, complicating treatment because a medication effective for one disorder may exacerbate the other. [More]
Complications from partial knee replacement is very small than total knee replacement

Complications from partial knee replacement is very small than total knee replacement

Partial knee replacement surgery is safer than total knee replacement, according to a new study published in The Lancet today (July 8). [More]
KoACT supplement optimal for bone strength, flexibility in post-menopausal women

KoACT supplement optimal for bone strength, flexibility in post-menopausal women

Data presented at April's Experimental Biology 2014 Annual Scientific Meeting shows that KoACT, a dietary supplement that combines a proprietary formulation of calcium and collagen is optimal for bone strength and flexibility in post-menopausal women. [More]
High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

It has been known for its flavorful addition to soups and as a delicacy for dogs but bone marrow fat may also have untapped health benefits, new research finds. [More]
Menopause-related changes in sex hormones linked to greater risk for heart disease

Menopause-related changes in sex hormones linked to greater risk for heart disease

As hormone levels change during the transition to menopause, the quality of a woman's cholesterol carriers degrades, leaving her at greater risk for heart disease, researchers at the University of Pittsburgh Graduate School of Public Health discovered. [More]
Molecule that blocks bone destruction could provide potential therapeutic target for osteoporosis

Molecule that blocks bone destruction could provide potential therapeutic target for osteoporosis

UT-Southwestern cancer researchers have identified a promising molecule that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone metastases of cancer. [More]
Ligand Pharmaceuticals, TG Therapeutics sign global license agreement for IRAK-4 inhibitors

Ligand Pharmaceuticals, TG Therapeutics sign global license agreement for IRAK-4 inhibitors

Ligand Pharmaceuticals Incorporated announced the signing of an exclusive global license agreement with TG Therapeutics, Inc. for the development and commercialization of Ligand's Interleukin-1 Receptor Associated Kinase-4 (IRAK-4) inhibitors. [More]
Guide to treating endocrine and metabolic emergencies released at ICE/ENDO 2014

Guide to treating endocrine and metabolic emergencies released at ICE/ENDO 2014

The Endocrine Society's publishing imprint Endocrine Press released its first original title, Endocrine and Metabolic Medical Emergencies, today during the Society's annual meeting, ICE/ENDO 2014. [More]
Patients continue to lose bone at least 2 years after bariatric surgery, shows study

Patients continue to lose bone at least 2 years after bariatric surgery, shows study

A new study shows that for at least two years after bariatric surgery, patients continue to lose bone, even after their weight stabilizes. [More]
Denosumab increases bone density for postmenopausal women with osteoporosis

Denosumab increases bone density for postmenopausal women with osteoporosis

Postmenopausal women with osteoporosis who take denosumab long-term have increased bone density, sustained low rate of fractures, and a favorable benefit/risk profile, a new multinational study finds. [More]
Researchers develop tissue engineered bone grafts for healing large bone defects

Researchers develop tissue engineered bone grafts for healing large bone defects

Bone is one of the most frequently transplanted tissues. And the demand is rising. Transplants treat large defects like those caused by trauma, complicated fractures, tumour resection or osteoporosis. [More]
New approach promises better drugs for diabetes and osteoporosis

New approach promises better drugs for diabetes and osteoporosis

By swapping replacement parts into the backbone of a synthetic hormone, UW-Madison graduate student Ross Cheloha and his mentor, Sam Gellman, along with collaborators at Harvard Medical School, have built a version of a parathyroid hormone that resists degradation in laboratory mice. [More]
Cranial ultrasound has greater sensitivity than temporal artery biopsy in diagnosis of GCA

Cranial ultrasound has greater sensitivity than temporal artery biopsy in diagnosis of GCA

A new study presented for the first time today at the European League Against Rheumatism Annual Congress (EULAR 2014), shows that cranial ultrasound has a greater sensitivity than temporal artery biopsy,* and a comparable specificity in the diagnosis of Giant Cell Arteritis (GCA). [More]