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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
WSU researchers working on better bone-like materials used in hip and knee replacements

WSU researchers working on better bone-like materials used in hip and knee replacements

Washington State University researchers are working to improve materials used in hip and knee replacements so that they last longer and allow patients to quickly get back on their feet after surgery. [More]
New study examines efficacy of brace application for treatment of spinal compression fractures

New study examines efficacy of brace application for treatment of spinal compression fractures

Compression fractures in the spine due to osteoporosis, a common condition causing progressive bone loss and increased fracture risk, are especially common in older women. A new study appearing in the December 3rd issue of the Journal of Bone & Joint Surgery found that patients who wore a brace as treatment for a spinal compression fracture had comparable outcomes in terms of pain, function and healing when compared to patients who did not wear a brace. [More]
Endocrinologist examines benefits and harms of testosterone therapy

Endocrinologist examines benefits and harms of testosterone therapy

An article in the latest edition of Australian Prescriber looks at the prescribing of testosterone, often used for ‘male menopause’ symptoms such as reduced energy, poor concentration and increased body fat. Over the past decade there has been a steep rise in the amount of testosterone dispensed in Australia and globally. [More]
Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases

Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases

Alizé Pharma III SAS, an Alizé Pharma group company specialized in the development of biopharmaceuticals to treat metabolic disorders and rare diseases, today announces that it has acquired exclusive worldwide rights to develop and commercialize a new family of peptides with bone anabolic properties. [More]
Study explores use of bisphosphonates for men receiving androgen deprivation therapy

Study explores use of bisphosphonates for men receiving androgen deprivation therapy

Although some guidelines recommend use of bisphosphonates (a class of drugs used to strengthen bone) for men on androgen deprivation therapy, an analysis finds that prescriptions for these drugs remains low, even for those men at high risk of subsequent fractures, according to a study in the December 3 issue of JAMA. [More]
Researchers use MRI techniques to study consequences of anorexia nervosa on brain structure

Researchers use MRI techniques to study consequences of anorexia nervosa on brain structure

Researchers from the Translational Developmental Neuroscience Lab led by Professor Stefan Ehrlich at the Department of Child and Adolescent Psychiatry and Psychotherapy of the University Hospital Carl Gustav Carus at the TU Dresden (Faculty of Medicine) used state-of-the-art magnetic resonance imaging (MRI) techniques to investigate the consequences of anorexia nervosa on brain structure. [More]
Commonly used osteoporosis medications may also prevent lung, breast and colon cancers

Commonly used osteoporosis medications may also prevent lung, breast and colon cancers

The most commonly used medications for osteoporosis worldwide, bisphosphonates, may also prevent certain kinds of lung, breast and colon cancers, according to two studies led by researchers at the Icahn School of Medicine at Mount Sinai and published today in the Proceedings of the National Academy of Sciences. [More]
Researchers discover molecular switch that triggers stress processes in the brain

Researchers discover molecular switch that triggers stress processes in the brain

At the Center for Brain Research at the MedUni Vienna an important factor for stress has been identified in collaboration with the Karolinska Institutet in Stockholm (Sweden). This is the protein secretagogin that plays an important role in the release of the stress hormone CRH and which only then enables stress processes in the brain to be transmitted to the pituitary gland and then onwards to the organs. [More]

Astronaut Koichi Wakata carried out live cell experiments with Leica Microsystems’ inverted research microscope

Astronaut Koichi Wakata of the Japan Aerospace Exploration Agency (JAXA) studied the effect of microgravity on bone density as well as on plants building their shape during his stay in the International Space Station (ISS) with an inverted research microscope by Leica Microsystems, the Leica DMI6000 B. He returned to earth with new data from several experiments at the ISS module "Kibo" which will now be evaluated and analyzed by him and collaborating scientists at Japanese research institutions. [More]
A practical toolkit to implement coordinator-based fracture liaison services

A practical toolkit to implement coordinator-based fracture liaison services

Health authorities worldwide are coping with rising costs and disability resulting from fragility fractures in the older population. [More]
Surprise WHI finding points to age, not menopause, as a risk factor for pelvic organ prolapse

Surprise WHI finding points to age, not menopause, as a risk factor for pelvic organ prolapse

Removing ovaries at hysterectomy does not increase a woman's risk of pelvic organ prolapse after menopause. In fact, removing ovaries lowers the risk of prolapse. This surprising finding from a Women's Health Initiative study was published online this week in Menopause, the journal of The North American Menopause Society. [More]
New Mayo Clinic study shows impact of long-term use of proton pump inhibitors

New Mayo Clinic study shows impact of long-term use of proton pump inhibitors

Before reaching for that daily antacid, you might consider what it's doing to the trillions of bugs living in your gut. A new Mayo Clinic study in the open access journal Microbiome shows that people who regularly take proton pump inhibitors (PPIs) have less diversity among their gut bacteria, putting them at increased risk for infections like clostridium difficile and pneumonia, in addition to vitamin deficiencies and bone fractures. [More]
Researchers make significant breakthrough for sufferers of bone disease

Researchers make significant breakthrough for sufferers of bone disease

Researchers in bone tissue regeneration believe they have made a significant breakthrough for sufferers of bone trauma, disease or defects such as osteoporosis. [More]
Endocrine Society issues Clinical Practice Guideline on rare bone condition

Endocrine Society issues Clinical Practice Guideline on rare bone condition

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of Paget's disease of the bone, a condition where one or more bones in the body become oversized and weak. [More]
Juvenile Arthritis Campaign launched to raise awareness about arthritis

Juvenile Arthritis Campaign launched to raise awareness about arthritis

Arthritis & Osteoporosis NSW has recently launched the Juvenile Arthritis Campaign aimed at raising much needed awareness and funds for the thousands of children struggling with arthritis throughout NSW. More than 6,000 children live with the condition and there are many more yet to be diagnosed. [More]
Study finds link between body weight change and hip fracture risk among Singapore Chinese

Study finds link between body weight change and hip fracture risk among Singapore Chinese

While a low body mass index (BMI) of less than 20 kg/m2 has been shown to be an independent risk factor for hip fractures, far less is known about the relationship of body weight changes on hip fracture risk. [More]
Hip fracture patients have lower mortality rate in smaller hospital departments

Hip fracture patients have lower mortality rate in smaller hospital departments

For several years the Danish health service has been moving towards increased centralisation and specialisation in large hospital departments based on the thesis that this provides better results for patients. [More]
Effective health interventions needed to increase life expectancy of older people

Effective health interventions needed to increase life expectancy of older people

A major new Series on health and ageing, published in "The Lancet", warns that unless health systems find effective strategies to address the problems faced by an ageing world population, the growing burden of chronic disease will greatly affect the quality of life of older people. As people across the world live longer, soaring levels of chronic illness and diminished wellbeing are poised to become a major global public health challenge. [More]
Osteoporosis drugs may also benefit patients with tumours outside the skeleton

Osteoporosis drugs may also benefit patients with tumours outside the skeleton

Australian researchers have shown why calcium-binding drugs commonly used to treat people with osteoporosis, or with late-stage cancers that have spread to bone, may also benefit patients with tumours outside the skeleton, including breast cancer. [More]
Dietary supplement KoACT is superior to calcium, vitamin D for bone health, study reveals

Dietary supplement KoACT is superior to calcium, vitamin D for bone health, study reveals

A new study by a Florida State University researcher reveals that a new dietary supplement is superior to calcium and vitamin D when it comes to bone health. [More]