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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Prune consumption may prevent bone mineral density loss in older population

Prune consumption may prevent bone mineral density loss in older population

As the demographic shift to an older population continues, a growing number of men and women will be diagnosed with osteoporosis. In addition to existing drug therapies, certain lifestyle and nutritional factors are known to reduce its risk. [More]
Exercise helps mitigate side effects of AIs in breast cancer survivors

Exercise helps mitigate side effects of AIs in breast cancer survivors

A researcher at Syracuse University has simple advice for breast cancer survivors struggling with the side effects of Aromatase Inhibitors (AIs): exercise. [More]

Researchers develop promising method for producing nanofibres to aid healing of bone fractures

In future, it may be possible to use nanofibres to improve the attachment of bone implants, or the fibres may be used directly to scaffold bone regeneration. This would aid the healing of fractures and may enable the care of osteoporosis. This is detailed in a new dissertation. [More]
Chemotherapy-induced senescent cells promote side effects and cancer relapse

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body. [More]
Antidepressant use doubles hip fracture risk among elders with Alzheimer's disease

Antidepressant use doubles hip fracture risk among elders with Alzheimer's disease

Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer's disease, according to a new study from the University of Eastern Finland. [More]
SLU expert suggests viewing exercise as daily contribution that offers cumulative health benefits

SLU expert suggests viewing exercise as daily contribution that offers cumulative health benefits

Have you already faltered on your New Year's resolution to exercise regularly in 2017? Joined a gym, but only worked out two days so far? New workout gear still neatly folded with tags attached? Don't give up your admirable ambition just yet. Instead, consider a new attitude to refocus your approach toward your exercise goal. [More]
Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

If you're 65 or older and taking more than four medications, resolve to talk to your doctor about doing a New Year's triage to make sure too many pills aren't making you sick, advises Milta Little, D.O., associate professor of geriatrics at Saint Louis University. [More]
New review explores approaches for prevention of hip fracture in very high risk patients

New review explores approaches for prevention of hip fracture in very high risk patients

Hip fractures are of great concern as they are the most severe type of fracture in osteoporotic patients, associated with premature death, and commonly leading to long-term physical disability, impaired capacity to perform daily activities and live independently, and reduced quality of life. [More]
NIH-funded scientists work with three ‘omes’ to understand human health

NIH-funded scientists work with three ‘omes’ to understand human health

Have you ever collected coins, cards, toy trains, stuffed animals? Did you feel the need to complete the set? If so, then you may be a completist. A completist will go to great lengths to acquire a complete set of something. [More]
Researchers use worms as model system to study how gut microbiome influences disease

Researchers use worms as model system to study how gut microbiome influences disease

The billions of microorganisms living within the human digestive tract appear to play a significant role in health and disease, notably metabolic syndrome, autoimmune disorders and diabetes - but how these organisms do so is not well understood. [More]
Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Women with inherited mutations in the BRCA1 or BRCA2 genes are at substantially higher risk of breast cancer. For these women, effective prevention strategies are their best hope to reduce their breast cancer risk. [More]
Research redefines role of Spop protein during bone development

Research redefines role of Spop protein during bone development

Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes -- a condition known as brachydactyly. T [More]
Griffith research aims to reduce complications, high costs with nano-engineered dental implants

Griffith research aims to reduce complications, high costs with nano-engineered dental implants

The complications and high costs associated with dental implants could be a thing of the past as Griffith research aims to reduce the associated risks of infection using new cutting edge nanotechnology. [More]
Menopausal women may experience accelerated decline in lung function, research shows

Menopausal women may experience accelerated decline in lung function, research shows

Menopausal women appear to experience an accelerated decline in lung function, according to new research published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. [More]
Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Increased risk of fracture has been shown to be one of the complications arising from longstanding diabetes. With the worldwide increase in Type 2 Diabetes (T2D), in part due to aging populations, there is also increasing concern about how to identify and manage patients with diabetes who are at high risk of osteoporotic fracture. [More]
Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD). [More]
New guidelines recommend evaluation of osteoporosis risk for all postmenopausal women

New guidelines recommend evaluation of osteoporosis risk for all postmenopausal women

Osteoporosis is preventable and treatable, but only a small proportion of people at risk for fractures are evaluated and treated, according to new osteoporosis guidelines written by an expert panel headed by Loyola Medicine endocrinologist Pauline M. Camacho, MD, FACE. [More]
Already available drug accelerates healing process after hip fracture

Already available drug accelerates healing process after hip fracture

An already available drug can help patients get back on their feet more rapidly after a hip fracture, according to an international study published in the Journal of Bone Joint Surgery. [More]
Study shows menopausal hormone therapy can improve bone mass and structure

Study shows menopausal hormone therapy can improve bone mass and structure

Women who undergo hormone therapy for menopausal symptoms such as hot flashes can not only increase bone mass, but also can improve bone structure, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

The length of your telomeres appears to be a window into your heart health and longevity, and scientists are measuring them to see if vitamin D and omega-3 supplements really improve both. [More]
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