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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Research redefines role of Spop protein during bone development

Research redefines role of Spop protein during bone development

Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes -- a condition known as brachydactyly. T [More]
Griffith research aims to reduce complications, high costs with nano-engineered dental implants

Griffith research aims to reduce complications, high costs with nano-engineered dental implants

The complications and high costs associated with dental implants could be a thing of the past as Griffith research aims to reduce the associated risks of infection using new cutting edge nanotechnology. [More]
Menopausal women may experience accelerated decline in lung function, research shows

Menopausal women may experience accelerated decline in lung function, research shows

Menopausal women appear to experience an accelerated decline in lung function, according to new research published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. [More]
Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Increased risk of fracture has been shown to be one of the complications arising from longstanding diabetes. With the worldwide increase in Type 2 Diabetes (T2D), in part due to aging populations, there is also increasing concern about how to identify and manage patients with diabetes who are at high risk of osteoporotic fracture. [More]
Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD). [More]
New guidelines recommend evaluation of osteoporosis risk for all postmenopausal women

New guidelines recommend evaluation of osteoporosis risk for all postmenopausal women

Osteoporosis is preventable and treatable, but only a small proportion of people at risk for fractures are evaluated and treated, according to new osteoporosis guidelines written by an expert panel headed by Loyola Medicine endocrinologist Pauline M. Camacho, MD, FACE. [More]
Already available drug accelerates healing process after hip fracture

Already available drug accelerates healing process after hip fracture

An already available drug can help patients get back on their feet more rapidly after a hip fracture, according to an international study published in the Journal of Bone Joint Surgery. [More]
Study shows menopausal hormone therapy can improve bone mass and structure

Study shows menopausal hormone therapy can improve bone mass and structure

Women who undergo hormone therapy for menopausal symptoms such as hot flashes can not only increase bone mass, but also can improve bone structure, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

The length of your telomeres appears to be a window into your heart health and longevity, and scientists are measuring them to see if vitamin D and omega-3 supplements really improve both. [More]
Benefits of consuming dried fruits and nuts

Benefits of consuming dried fruits and nuts

A 2015 study observed that tree nut intake was associated with a decrease in total cholesterol, LDL, "bad", cholesterol and triglycerides. [More]
Biologic drugs may help prevent progressive bone loss in patients with RA

Biologic drugs may help prevent progressive bone loss in patients with RA

A new review by the International Osteoporosis Foundation Chronic Inflammation and Bone Structure Working Group concludes that early and aggressive treatment of Rheumatoid Arthritis (RA) with biologic drugs, specifically biological disease-modifying anti-rheumatic drugs (DMARDs), may be most effective in halting progressive bone loss in patients with RA. [More]
Suppressing bone specific protein can alleviate radiotherapy-induced osteoporosis

Suppressing bone specific protein can alleviate radiotherapy-induced osteoporosis

Radiotherapy destroys cancer cells using high-energy ionizing radiation to damage DNA and induce cell death. About two million patients per year in the United States - more than 50 percent of all cancer patients -- receive radiotherapy at some stage during their illness, either alone or in combination with chemotherapy, surgery, and targeted medicines. [More]
Risk of fracture still higher among women experiencing early menopause

Risk of fracture still higher among women experiencing early menopause

If you're in menopause before the age of 40, you have a higher fracture risk. That fact has already been proven by the Women's Health Initiative clinical trials. Now a new study evaluating the same WHI data further concludes that, even with calcium and vitamin D supplements, your risk of fracture is still higher. [More]
Study shows promise for successful ovarian transplantation in future

Study shows promise for successful ovarian transplantation in future

Approximately 11% of women worldwide suffer from premature ovarian failure. This can have many different causes: chemotherapy administered for a malignant disease might irreversibly damage the ovaries and, because of the advances in modern cancer therapy, the number of young women surviving cancer is on the increase. [More]
HSS conducts survey to assess musculoskeletal health needs of surrounding communities

HSS conducts survey to assess musculoskeletal health needs of surrounding communities

Hospital for Special Surgery, which has an Outpatient Center in Stamford, plans to increase outreach and educational programs to meet the needs of surrounding communities. [More]
Individualized vitamin D supplementation may benefit women during pregnancy

Individualized vitamin D supplementation may benefit women during pregnancy

Individualized supplement doses help protect pregnant women from vitamin D deficiency, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
New minimally invasive approach to diagnose hyperparathyroidism

New minimally invasive approach to diagnose hyperparathyroidism

Almost all of us have four parathyroid glands, located next to the thyroid gland in the neck. They are an organ only the size of a grain of rice, but critical for controlling our body's calcium levels. [More]
Simple treatment can help relieve majority of back pain

Simple treatment can help relieve majority of back pain

During their lifetime, as many as eight out of ten people experience back pain that lasts more than three days. However, for a vast majority of these people, the pain goes away with simple treatment. [More]
Molecular signaling pathway could be basis of potential new treatment for osteoporosis

Molecular signaling pathway could be basis of potential new treatment for osteoporosis

A molecular signaling pathway identified by an international research team could be the basis of improved treatment for osteoporosis. [More]
Study finds adequate levels of vitamin D among adolescents in the UK

Study finds adequate levels of vitamin D among adolescents in the UK

A study, published in the American Journal of Clinical Nutrition, has shown high levels of vitamin D inadequacy in UK adolescents, and - for the first time - identified the intake needed by adolescents in order to maintain adequate serum vitamin D levels during the winter time. [More]
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