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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
New osteoporosis drug may also be useful for treating brittle bone disease

New osteoporosis drug may also be useful for treating brittle bone disease

New research at the University of Michigan offers evidence that a drug being developed to treat osteoporosis may also be useful for treating osteogenesis imperfecta or brittle bone disease, a rare but potentially debilitating bone disorder that that is present from birth. [More]
FLS could reduce healthcare costs associated with osteoporotic fractures

FLS could reduce healthcare costs associated with osteoporotic fractures

Using a simulation model, Swedish researchers have shown that the implementation of Fracture Liaison Services (FLS) could considerably reduce the human and healthcare costs associated with osteoporotic fractures. The results from the model were presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Milan. [More]
New study estimates UK hospital costs of hip fracture

New study estimates UK hospital costs of hip fracture

A new study presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases reveals the high cost of first and subsequent hip fractures to the healthcare system in the UK. [More]
UAB scientist explores the bone development function of runx2 gene

UAB scientist explores the bone development function of runx2 gene

Amjad Javed, Ph.D., of the University of Alabama at Birmingham, has taken a major step forward in understanding the bone development function of a gene called runx2, which could lead to future ways to speed bone healing, aid bone bioengineering, stem osteoporosis and reduce arthritis. [More]
Top experts focus on musculoskeletal disorders in open key Congress in Milan

Top experts focus on musculoskeletal disorders in open key Congress in Milan

Musculoskeletal conditions, which affect over 1.7 billion people worldwide, will be the focus of a major four-day Congress which opens today in Milan, Italy. [More]
Arthritis & Osteoporosis NSW to hold Clinical Update for 2015 for health professionals

Arthritis & Osteoporosis NSW to hold Clinical Update for 2015 for health professionals

Arthritis is a condition that affects over 1.1 million people in NSW and over 3 million people across Australia and with an ageing population, that figure is projected to reach 7 million by 2050. Arthritis is a condition which affects people across all ages, backgrounds, men and women alike. [More]
VIVA physician selected as new Fellows in the Society of Interventional Radiology

VIVA physician selected as new Fellows in the Society of Interventional Radiology

Dr. John D. Statler, a board-certified, fellowship-trained Interventional Radiologist with Virginia Interventional & Vascular Associates, is one of only 23 physicians nationwide selected this year as new Fellows in the Society of Interventional Radiology. [More]
Bisphosphonate treatment following distal radius fracture associated with atypical femur fractures

Bisphosphonate treatment following distal radius fracture associated with atypical femur fractures

Osteoporosis is a disease of progressive bone loss affecting more than 44 million Americans and contributing to an estimated 2 million bone fractures each year. [More]

Arthritis Awareness Week capped off with amazing William's Walk event

Hundreds of people joined Arthritis & Osteoporosis NSW in walking Parramatta Park in aid of juvenile arthritis, a condition that is rarely discussed in the community. William’s Walk was crucial in getting the word out that juvenile arthritis affects 6000+ children throughout NSW, raising over $50,000 in the process. [More]
Oxis Biotech executes licensing agreement with MCIT for development of antibody-drug conjugates

Oxis Biotech executes licensing agreement with MCIT for development of antibody-drug conjugates

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of a definitive licensing and development agreement with MultiCell Immunotherapeutics, Inc. concerning the development of certain antibody-drug conjugates (ADCs). [More]
Fracture prevention project could help save millions

Fracture prevention project could help save millions

Bone fractures affect millions of people across the UK with 1 in 2 women and 1 in 5 men over the age of 50 suffering from them . The cost of fragility fractures place a substantial economic burden on the health and social care system with the costs of fragility fractures in the region of £2.3bn . [More]

Camp Twinkletoes educates, supports and inspires children and teenagers with arthritis

Each year, Arthritis & Osteoporosis NSW is proud to host two special camps for children and teenagers with arthritis. Camp Twinkletoes is one of these camps and we visited Stanwell Tops on 20-22 February to set about educating, supporting and inspiring some very special families and their children with arthritis. [More]
TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Pharmaceuticals, Inc. today announced that its fully owned subsidiary, TWi Biotechnology, Inc., has received the designation of Rare Disease Drug by Taiwan FDA for use of AC-203 to treat Epidermolysis Bullosa Simplex (EBS), and is eligible for applying for coverage under National Health Insurance Administration. [More]
Researchers identify new class of drugs that slows aging process

Researchers identify new class of drugs that slows aging process

A research team from The Scripps Research Institute, Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan. [More]
Investigational drug for postmenopausal osteoporosis reduces rate of new spinal fractures

Investigational drug for postmenopausal osteoporosis reduces rate of new spinal fractures

Abaloparatide-SC, an injectable drug being studied for the treatment of postmenopausal osteoporosis, reduces the rate of new spinal fractures by a statistically significant 86 percent and as well as statistically significant reductions in the fracture rate at other parts of the body, a phase 3 clinical trial finds. Results of the ACTIVE fracture prevention trial will be described in a late-breaking oral presentation Thursday at the Endocrine Society's 97th annual meeting in San Diego. [More]
Severe mortality-associated diseases less prevalent in members of long-lived families

Severe mortality-associated diseases less prevalent in members of long-lived families

Recent research from the Long Life Family Study (LLFS) confirms that severe mortality-associated diseases are less prevalent in the families of long-lived individuals than in the general population. The Journals of Gerontology, Series A will publish these findings in the article titled, "Are Members of Long-Lived Families Healthier than Their Equally Long-Lived Peers? Evidence from the Long Life Family Study" on March 5, 2015. [More]
New guidance to prevent bisphosphonate-related atypical femoral fractures

New guidance to prevent bisphosphonate-related atypical femoral fractures

Physicians worldwide frequently prescribe bisphosphonates such as alendronate (Fosamax) and ibandronate (Boniva) to treat osteoporosis and prevent fragility fractures. Unfortunately, long-term bisphosphonate use has been linked to an increased risk of atypical femoral fractures. [More]
Study debunks false reports surrounding risk of hormone therapy

Study debunks false reports surrounding risk of hormone therapy

For over a decade, hormone therapy (HT) has been a hot topic in medicine. Unfortunately, women are still confused and concerned about using HT after two federally-funded studies linked HT to potentially serious health risks. [More]
Scientists discover DNA vaccine that alleviates chronic inflammation in the body

Scientists discover DNA vaccine that alleviates chronic inflammation in the body

An international team of scientists including CureLab Oncology, Inc. (Boston), University of Camerino (Italy), and Boston University have serendipitously discovered a DNA vaccine, which systemically alleviates chronic inflammation in the body. Since osteoporosis is an inflammatory disease, preventive and therapeutic effects of the new vaccine were demonstrated on mouse models with osteoporosis. [More]
High-impact exercise improves patellar cartilage quality of postmenopausal women at risk of osteoporosis

High-impact exercise improves patellar cartilage quality of postmenopausal women at risk of osteoporosis

Progressive high-impact training improved the patellar cartilage quality of the postmenopausal women who may be at risk of osteoporosis (bone loss) as well as at risk of osteoarthritis. [More]
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