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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

A Mayo Clinic research team has found evidence suggesting that the controversial practice of ovary removal in premenopausal women to prevent ovarian cancer should be discontinued in women who are not at high risk of cancer. [More]
Does exercise eliminate the ill effects of sitting? An interview with Prof. Ulf Ekelund

Does exercise eliminate the ill effects of sitting? An interview with Prof. Ulf Ekelund

In short, the detrimental effects of sitting for prolonged hours can be divided into acute, or short-term, and long-term effects. [More]
New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide-SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with osteoporosis regardless of their baseline bone density, age, and previous history of fracture. [More]
Incorporating laughter into exercise program could provide health benefits to older adults

Incorporating laughter into exercise program could provide health benefits to older adults

Incorporating laughter into a physical activity program that is focused on strength, balance and flexibility could improve older adults' mental health, aerobic endurance and confidence in their ability to exercise, according to a study led by Georgia State University. [More]
Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model. [More]
Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

Chemists from Trinity College Dublin in collaboration with RCSI have devised a revolutionary new scanning technique that produces extremely high-res 3D images of bones -- without exposing patients to X-ray radiation. [More]
International conference on longevity to be held in Brussels for 3 days

International conference on longevity to be held in Brussels for 3 days

The Eurosymposium on Healthy Ageing is an international event that provides a unique opportunity for researchers, government officials, biotech executives, entrepreneurs, and non-governmental institutions from around the world to meet, network, and forge new scientific collaborations. [More]
Researchers discover risk factors that contribute to fracture nonunion in adults

Researchers discover risk factors that contribute to fracture nonunion in adults

Dr. Robert Zura, the Robert D'Ambrosia Professor and Head of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team that identified risk factors which may help orthopaedic surgeons better predict a serious complication of bone fractures. [More]
School-based exercises may benefit bone mass, strength in growing children

School-based exercises may benefit bone mass, strength in growing children

Moderate to high impact sports such as gymnastics, basketball, or football have been shown to benefit bone mass, structure and strength - with benefits particularly apparent during pre-and early adolescence. [More]
Beta-blockers can help treat bone loss caused by antidepressants in mice

Beta-blockers can help treat bone loss caused by antidepressants in mice

The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found. [More]
JMU scientists crystallize new inhibitory antibodies targeting sclerostin

JMU scientists crystallize new inhibitory antibodies targeting sclerostin

Osteoporosis particularly affects elderly women: the bone's structure weakens and the risk of suffering fractures rises. [More]
Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Supplementing with soluble corn fiber at two critical times in a woman's life - adolescence and post-menopause - can help build and retain calcium in bone, according to new research from Purdue University. [More]
Vertebroplasty helps decrease acute pain in patients with osteoporotic fractures

Vertebroplasty helps decrease acute pain in patients with osteoporotic fractures

Vertebroplasty is a safe and effective procedure to reduce acute pain and disability in patients who have experienced spinal fractures within a 6-week period, according to a new study published this week in The Lancet. [More]
Scientists discover way to visualize function of bone-resorbing cells in living mice

Scientists discover way to visualize function of bone-resorbing cells in living mice

Researchers of Osaka University have discovered a way to visualize sites where bone-resorbing cells (osteoclasts) were in the process of resorbing bone in living mice. [More]
Mayo Clinic, Geroscience Network researchers aim to accelerate pace of aging research

Mayo Clinic, Geroscience Network researchers aim to accelerate pace of aging research

Mayo Clinic, along with other members of the Geroscience Network, has published six manuscripts that map strategies for taking new drugs that target processes underlying aging into clinical trials. [More]
IMS provides global recommendations for care of women at menopause

IMS provides global recommendations for care of women at menopause

The International Menopause Society has brought together 7 international Societies to provide harmonised, global recommendations for the care of women at menopause [More]
New Griffith study aims to determine optimum mode of exercise to improve bone strength of young women

New Griffith study aims to determine optimum mode of exercise to improve bone strength of young women

Young women may think osteoporosis is an older person’s problem but a new study at Griffith University is helping show them that prevention is better than cure. [More]
New review highlights usefulness of BTMs in monitoring efficacy of osteoporosis treatment

New review highlights usefulness of BTMs in monitoring efficacy of osteoporosis treatment

A new review published by a joint scientific working group of the International Federation of Clinical Chemistry and Laboratory Medicine and the International Osteoporosis Foundation finds that current evidence continues to support the potential for bone turnover markers (BTMs) to provide clinically useful information for monitoring osteoporosis treatment. [More]
PolyU researchers discover inadequate intakes of micronutrients among Hong Kong lactating women

PolyU researchers discover inadequate intakes of micronutrients among Hong Kong lactating women

While breastfeeding has become more common across the globe in recent years, lactating women may not be aware of the nutrient adequacy of their breast milk and how their daily diet affects their nutrition intakes. [More]
TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

In addition to its more obvious ills, type 2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options. [More]
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