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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
New ultrasound method offers increasingly personalised and earlier assessment of fracture risk

New ultrasound method offers increasingly personalised and earlier assessment of fracture risk

In people over 50 years of age, fractures are so common that for example one in three women will suffer a wrist, ankle or hip fracture during their life. Low-energy fractures caused by bone weakening are one manifestation of osteoporosis. [More]
Moderate calcium intake not linked to coronary artery calcification, says UAB cardiologist

Moderate calcium intake not linked to coronary artery calcification, says UAB cardiologist

A study recently published in the Journal of the American Heart Association is prompting headlines like "Calcium supplements might hurt your heart." [More]
Heavy cannabis users have large reduction in bone density, increased risk of bone fractures

Heavy cannabis users have large reduction in bone density, increased risk of bone fractures

People who regularly smoke large amounts of cannabis have reduced bone density and are more prone to fractures, research has found. [More]
Calcium supplements may raise risk of plaque buildup in arteries and heart damage

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

After analyzing 10 years of medical tests on more than 2,700 people in a federally funded heart disease study, researchers at Johns Hopkins Medicine and elsewhere conclude that taking calcium in the form of supplements may raise the risk of plaque buildup in arteries and heart damage, although a diet high in calcium-rich foods appears be protective. [More]
New casting technique could help avoid surgery in elderly patients with unstable ankle fractures

New casting technique could help avoid surgery in elderly patients with unstable ankle fractures

Elderly patients with unstable ankle fractures could avoid surgery, according to research by a UK team led by Oxford University. [More]
Watching fat-derived stem cells transform offers clues to combating osteoporosis in older women

Watching fat-derived stem cells transform offers clues to combating osteoporosis in older women

For years, scientists have studied how stem cells might be used to treat many diseases, including osteoporosis. [More]
New review shows both types of diabetes increase risk of fragility fractures

New review shows both types of diabetes increase risk of fragility fractures

Recent research has shown that bone health is compromised in people with diabetes, resulting in a significantly higher risk of fragility fracture. [More]
Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

A Mayo Clinic research team has found evidence suggesting that the controversial practice of ovary removal in premenopausal women to prevent ovarian cancer should be discontinued in women who are not at high risk of cancer. [More]
Does exercise eliminate the ill effects of sitting? An interview with Prof. Ulf Ekelund

Does exercise eliminate the ill effects of sitting? An interview with Prof. Ulf Ekelund

In short, the detrimental effects of sitting for prolonged hours can be divided into acute, or short-term, and long-term effects. [More]
New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide-SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with osteoporosis regardless of their baseline bone density, age, and previous history of fracture. [More]
Incorporating laughter into exercise program could provide health benefits to older adults

Incorporating laughter into exercise program could provide health benefits to older adults

Incorporating laughter into a physical activity program that is focused on strength, balance and flexibility could improve older adults' mental health, aerobic endurance and confidence in their ability to exercise, according to a study led by Georgia State University. [More]
Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model. [More]
Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

Chemists from Trinity College Dublin in collaboration with RCSI have devised a revolutionary new scanning technique that produces extremely high-res 3D images of bones -- without exposing patients to X-ray radiation. [More]
International conference on longevity to be held in Brussels for 3 days

International conference on longevity to be held in Brussels for 3 days

The Eurosymposium on Healthy Ageing is an international event that provides a unique opportunity for researchers, government officials, biotech executives, entrepreneurs, and non-governmental institutions from around the world to meet, network, and forge new scientific collaborations. [More]
Researchers discover risk factors that contribute to fracture nonunion in adults

Researchers discover risk factors that contribute to fracture nonunion in adults

Dr. Robert Zura, the Robert D'Ambrosia Professor and Head of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team that identified risk factors which may help orthopaedic surgeons better predict a serious complication of bone fractures. [More]
School-based exercises may benefit bone mass, strength in growing children

School-based exercises may benefit bone mass, strength in growing children

Moderate to high impact sports such as gymnastics, basketball, or football have been shown to benefit bone mass, structure and strength - with benefits particularly apparent during pre-and early adolescence. [More]
Beta-blockers can help treat bone loss caused by antidepressants in mice

Beta-blockers can help treat bone loss caused by antidepressants in mice

The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found. [More]
JMU scientists crystallize new inhibitory antibodies targeting sclerostin

JMU scientists crystallize new inhibitory antibodies targeting sclerostin

Osteoporosis particularly affects elderly women: the bone's structure weakens and the risk of suffering fractures rises. [More]
Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Supplementing with soluble corn fiber at two critical times in a woman's life - adolescence and post-menopause - can help build and retain calcium in bone, according to new research from Purdue University. [More]
Vertebroplasty helps decrease acute pain in patients with osteoporotic fractures

Vertebroplasty helps decrease acute pain in patients with osteoporotic fractures

Vertebroplasty is a safe and effective procedure to reduce acute pain and disability in patients who have experienced spinal fractures within a 6-week period, according to a new study published this week in The Lancet. [More]
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