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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Embryonic stem cell gene Nanog holds potential for reversing effects of aging

Embryonic stem cell gene Nanog holds potential for reversing effects of aging

The fountain of youth may reside in an embryonic stem cell gene named Nanog. [More]
Study finds older adults who sustain wrist fractures more likely to have poor balance

Study finds older adults who sustain wrist fractures more likely to have poor balance

Elderly patients suffering a low energy wrist (distal radius) fracture are more likely to have difficulties with balance, placing them at risk for future injuries, according to a new study appearing in the July 20, 2016 issue of the Journal of Bone and Joint Surgery. [More]
Study finds low rates of baseline BMD testing among older women with breast cancer

Study finds low rates of baseline BMD testing among older women with breast cancer

Aromatase inhibitors (AIs)—drugs that stop the production of estrogen in women—are standard adjuvant therapy for post-menopausal women with hormone-receptor positive breast cancer. [More]
Maturitas provides new holistic model of care for healthy menopause

Maturitas provides new holistic model of care for healthy menopause

A new position statement by the European Menopause and Andropause Society published in the journal Maturitas provides a holistic model of care for healthy menopause. [More]
Study shows twice daily exercise intervention improves bone strength in VLBW pre-term infants

Study shows twice daily exercise intervention improves bone strength in VLBW pre-term infants

Because of their low weight and premature birth, very low birth weight (VLBW) pre-term infants have lower bone mineral mass and a greater need for bone nutrients compared to most new-born infants. [More]
Watching TV for long hours during childhood linked to lower bone mineral content

Watching TV for long hours during childhood linked to lower bone mineral content

Consistently watching high levels of television during childhood and adolescence were linked with lower peak bone mass at age 20 years in a recent study. [More]
Fraunhofer scientists show how seaweed has potential to substitute salt

Fraunhofer scientists show how seaweed has potential to substitute salt

Salt (sodium chloride) is an essential nutrient, but one that is often present in surprising quantities in industrially processed foods. [More]
Buck researchers find new way for possible treatment of AMD

Buck researchers find new way for possible treatment of AMD

Buck researchers boosted the potency of a broccoli-related compound by ten times and identified it as a possible treatment for age-related macular degeneration (AMD), the leading cause of vision loss affecting more than 10 million older Americans. [More]
Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine. [More]
Menopause symptoms: can a healthcare professional help? An interview with Dr Heather Currie

Menopause symptoms: can a healthcare professional help? An interview with Dr Heather Currie

The survey showed that only 50% of women consulted a healthcare professional about their symptoms, despite the fact that many women said their symptoms were having a significant effect on their work life, social life, home life and sex life. [More]
Study finds delayed onset of illness for centenarians than younger counterparts

Study finds delayed onset of illness for centenarians than younger counterparts

Research has shown that the human lifespan has the potential to be extended. But would this merely mean people living longer in poor health? The upbeat findings from a new study in the Journal of the American Geriatrics Society indicate that those extra years could well be healthy ones [More]
Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses. [More]

JBMR article highlights controversies in treating high-risk osteoporosis patients

The remarkable progress made over the past 30 years to reduce fractures and dramatically improve the quality of life for millions of osteoporosis patients is rapidly being reversed, say two bone health experts in a Journal of Bone and Mineral Research article published online today. [More]
Bone Balance Index may help predict bone loss in women during menopause transition

Bone Balance Index may help predict bone loss in women during menopause transition

Researchers have developed an index to better predict which women may experience faster bone loss across the menopause transition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
IOF urges clinicians in Asia to prepare for escalating crisis of osteoporosis among elderly people

IOF urges clinicians in Asia to prepare for escalating crisis of osteoporosis among elderly people

The International Osteoporosis Foundation is calling on doctors in the Asia-Pacific region to prepare for an immense rise in the number of elderly people suffering broken bones as a result of osteoporosis. [More]
Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development. [More]
Study examines effectiveness of high-load resistance training in improving older men’s bone strength

Study examines effectiveness of high-load resistance training in improving older men’s bone strength

Big improvements in bone and muscle strength with no injuries is expected to be the outcome of a Griffith University study training men aged over 50 with low bone mass. [More]
Complex 36-point therapeutic personalized program can help reverse memory loss in early AD patients

Complex 36-point therapeutic personalized program can help reverse memory loss in early AD patients

Results from quantitative MRI and neuropsychological testing show unprecedented improvements in ten patients with early Alzheimer's disease (AD) or its precursors following treatment with a programmatic and personalized therapy. Results from an approach dubbed metabolic enhancement for neurodegeneration are now available online in the journal Aging. [More]
Researchers explore why women have ubiquitous survival advantage than men

Researchers explore why women have ubiquitous survival advantage than men

Women live longer than men. This simple statement holds a tantalizing riddle that Steven Austad, Ph.D., and Kathleen Fischer, Ph.D., of the University of Alabama at Birmingham explore in a perspective piece published in Cell Metabolism on June 14. [More]
Rehabilitation programmes can help reverse frailty in older COPD patients

Rehabilitation programmes can help reverse frailty in older COPD patients

One in four patients with COPD referred for exercise rehabilitation are frail, but nevertheless can respond favourably to rehabilitation and their frailty can be reversed, finds a new study led by King's College London and Royal Brompton & Harefield NHS Foundation Trust. [More]
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