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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Unhealthy diet, lack of exercise speed up onset of age-related conditions in mice

Unhealthy diet, lack of exercise speed up onset of age-related conditions in mice

Could an unhealthy diet and lack of exercise be making you age faster? Researchers at Mayo Clinic believe there is a link between these modifiable lifestyle factors and the biological processes of aging. In a recent study, researchers demonstrated that a poor diet and lack of exercise accelerated the onset of cellular senescence and, in turn, age-related conditions in mice. [More]
Psoriasis patients experience widespread bone loss

Psoriasis patients experience widespread bone loss

Researchers from the Genes, Development and Disease Group, headed by Erwin Wagner at the Spanish National Cancer Research Centre have discovered that psoriasis patients experience a widespread bone loss as a result of the disease. [More]
Fertility problems put men at increased risk of metabolic diseases

Fertility problems put men at increased risk of metabolic diseases

Men with fertility problems are at risk of metabolic diseases as they age, according to work being presented at the European Association of Urology conference in Munich [More]
Indego exoskeleton receives FDA certification for U.S. use

Indego exoskeleton receives FDA certification for U.S. use

The U.S. Food and Drug Administration (FDA) has given clearance to market and sell the powered lower-limb exoskeleton created by a team of Vanderbilt engineers and commercialized by the Parker Hannifin Corporation for both clinical and personal use in the United States. [More]
Low bone mass higher in HIV-infected males than in females

Low bone mass higher in HIV-infected males than in females

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals - assessed by sex and HIV status - to try to determine causes of this differential bone loss. [More]
Antidepressants may play role in dental implant failure

Antidepressants may play role in dental implant failure

Antidepressants, commonly used to treat anxiety, pain and other disorders, may play a role in dental implant failure, according to a new pilot study by University at Buffalo researchers. [More]
BetterYou’s DLuxPregnancy oral spray could boost vitamin D levels of expectant mums

BetterYou’s DLuxPregnancy oral spray could boost vitamin D levels of expectant mums

An innovative way of boosting the vitamin D levels of expectant mums could help to improve their babies’ bone health, say health pioneers BetterYou. [More]
Vitamin D supplements during pregnancy do not improve babies' bone health, but may have seasonal effect

Vitamin D supplements during pregnancy do not improve babies' bone health, but may have seasonal effect

Taking vitamin D supplements during pregnancy, as recommended for all women under UK guidelines, has no significant effect on the bone density of babies, according to the first randomised controlled trial of its kind, published in The Lancet Diabetes & Endocrinology journal. [More]
Kids who take ADHD medications show decreased bone density

Kids who take ADHD medications show decreased bone density

Children and adolescents who take medication for attention-deficit hyperactivity disorder (ADHD) show decreased bone density, according to a large cross-sectional study presented today at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons. [More]
Osteoporosis drugs linked to unusual fractures of the femur

Osteoporosis drugs linked to unusual fractures of the femur

Osteoporosis drugs have significantly reduced the risk of bone fractures for millions of people, but also have been linked to unusual fractures of the femur (thigh bone). [More]
Vitamin D supplementation during pregnancy can help increase bone strength in babies born in winter months

Vitamin D supplementation during pregnancy can help increase bone strength in babies born in winter months

Vitamin D supplementation during pregnancy may lead to stronger bones in babies born during the winter months, a new Southampton study has shown. [More]
Report: One in two Americans affected by musculoskeletal condition

Report: One in two Americans affected by musculoskeletal condition

An estimated 126.6 million Americans (one in two adults) are affected by a musculoskeletal condition--comparable to the total percentage of Americans living with a chronic lung or heart condition--costing an estimated $213 billion in annual treatment, care and lost wages, according to a new report issued today by the United States Bone and Joint Initiative. [More]
Low-sodium intake has little impact on bone health in postmenopausal women

Low-sodium intake has little impact on bone health in postmenopausal women

A low-salt diet does not necessarily translate to stronger bones in postmenopausal women, physician-scientists report. [More]
Single dose of zoledronic acid can inhibit bone loss in HIV-infected patients

Single dose of zoledronic acid can inhibit bone loss in HIV-infected patients

A single dose of the drug zoledronic acid was found to inhibit the bone loss that is common in HIV-infected patients and that is increased during the first two years of treatment with antiretroviral therapy (ART). [More]
Consuming dried plums can protect from radiation-induced bone loss

Consuming dried plums can protect from radiation-induced bone loss

Dr. Nancy Turner, a Texas A&M AgriLife Research scientist in College Station, was one of a team of researchers who recently studied different interventions to protect from radiation-induced bone loss. [More]
Romosozumab for postmenopausal women with osteoporosis meets co-primary endpoints in Phase 3 study

Romosozumab for postmenopausal women with osteoporosis meets co-primary endpoints in Phase 3 study

Amgen and UCB today announced top-line results from the Phase 3 placebo-controlled FRActure study in postmenopausal woMen with ostEoporosis (FRAME). [More]
Physical therapy reduces urinary problems in postmenopausal women with osteoporosis

Physical therapy reduces urinary problems in postmenopausal women with osteoporosis

After menopause, women with osteoporosis struggle more with urinary incontinence than women with healthy bones do. But physical therapy that includes pelvic floor muscle training can produce dramatic improvements, shows a study published online today in Menopause, the journal of The North American Menopause Society. [More]
People who feel older may end up in hospital as they age

People who feel older may end up in hospital as they age

People who feel older than their peers are more likely to be hospitalized as they age, regardless of their actual age or other demographic factors, according to research published by the American Psychological Association. [More]
Exercise-associated bone loading during adolescence, young adulthood benefits bone density in adulthood

Exercise-associated bone loading during adolescence, young adulthood benefits bone density in adulthood

Men have many reasons to add high-impact and resistance training to their exercise regimens; these reasons include building muscle and shedding fat. Now a University of Missouri researcher has determined another significant benefit to these activities: building bone mass. [More]
NOF provides evidence-based guidance to help children and adolescents attain optimal bone health

NOF provides evidence-based guidance to help children and adolescents attain optimal bone health

The National Osteoporosis Foundation today released a position statement providing evidence-based guidance and a national implementation strategy to help children and adolescents achieve optimal bone health, or what is known as "peak bone mass," early in life. [More]
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