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Osteoporosis is a progressive metabolic bone disease that causes a decrease in bone density and gives rise to weak, fragile bones that are prone to fracture. Most commonly, these fractures occur in the spine, wrist and hips when a person falls or bumps into something. If such an event triggers a visit to the doctor, a test of the bone mineral density called a DEXA scan may be performed and reveal osteoporosis.

The term osteoporosis refers to the porous (spongy) state of bone that eventually manifests as the bone’s ability to replenish itself declines over time. When individuals reach the age of around 40, the rate of bone breakdown starts to exceed the rate at which it is replaced, creating increasingly larger holes in the bone that make it less dense and more prone to fracture.

Some of the risk factors for osteoporosis such as gender, age and family history for the condition cannot be changed. However, factors such as diet and activity level can be improved to increase bone strength and individuals are advised to exercise regularly, eat a diet rich in vitamin D and calcium, and quit any smoking or drinking habits.

Osteoporosis is currently thought to be affecting more than 200 million people worldwide but is most common among older, post-menopausal women who have reduced levels of estrogen, an important contributor to bone health.
Arthritis Awareness Week capped off with amazing William's Walk event

Arthritis Awareness Week capped off with amazing William's Walk event

Hundreds of people joined Arthritis & Osteoporosis NSW in walking Parramatta Park in aid of juvenile arthritis, a condition that is rarely discussed in the community. William’s Walk was crucial in getting the word out that juvenile arthritis affects 6000+ children throughout NSW, raising over $50,000 in the process. [More]
Oxis Biotech executes licensing agreement with MCIT for development of antibody-drug conjugates

Oxis Biotech executes licensing agreement with MCIT for development of antibody-drug conjugates

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of a definitive licensing and development agreement with MultiCell Immunotherapeutics, Inc. concerning the development of certain antibody-drug conjugates (ADCs). [More]
Fracture prevention project could help save millions

Fracture prevention project could help save millions

Bone fractures affect millions of people across the UK with 1 in 2 women and 1 in 5 men over the age of 50 suffering from them . The cost of fragility fractures place a substantial economic burden on the health and social care system with the costs of fragility fractures in the region of £2.3bn . [More]
Camp Twinkletoes educates, supports and inspires children and teenagers with arthritis

Camp Twinkletoes educates, supports and inspires children and teenagers with arthritis

Each year, Arthritis & Osteoporosis NSW is proud to host two special camps for children and teenagers with arthritis. Camp Twinkletoes is one of these camps and we visited Stanwell Tops on 20-22 February to set about educating, supporting and inspiring some very special families and their children with arthritis. [More]
TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Pharmaceuticals, Inc. today announced that its fully owned subsidiary, TWi Biotechnology, Inc., has received the designation of Rare Disease Drug by Taiwan FDA for use of AC-203 to treat Epidermolysis Bullosa Simplex (EBS), and is eligible for applying for coverage under National Health Insurance Administration. [More]
Researchers identify new class of drugs that slows aging process

Researchers identify new class of drugs that slows aging process

A research team from The Scripps Research Institute, Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan. [More]
Investigational drug for postmenopausal osteoporosis reduces rate of new spinal fractures

Investigational drug for postmenopausal osteoporosis reduces rate of new spinal fractures

Abaloparatide-SC, an injectable drug being studied for the treatment of postmenopausal osteoporosis, reduces the rate of new spinal fractures by a statistically significant 86 percent and as well as statistically significant reductions in the fracture rate at other parts of the body, a phase 3 clinical trial finds. Results of the ACTIVE fracture prevention trial will be described in a late-breaking oral presentation Thursday at the Endocrine Society's 97th annual meeting in San Diego. [More]
Severe mortality-associated diseases less prevalent in members of long-lived families

Severe mortality-associated diseases less prevalent in members of long-lived families

Recent research from the Long Life Family Study (LLFS) confirms that severe mortality-associated diseases are less prevalent in the families of long-lived individuals than in the general population. The Journals of Gerontology, Series A will publish these findings in the article titled, "Are Members of Long-Lived Families Healthier than Their Equally Long-Lived Peers? Evidence from the Long Life Family Study" on March 5, 2015. [More]
New guidance to prevent bisphosphonate-related atypical femoral fractures

New guidance to prevent bisphosphonate-related atypical femoral fractures

Physicians worldwide frequently prescribe bisphosphonates such as alendronate (Fosamax) and ibandronate (Boniva) to treat osteoporosis and prevent fragility fractures. Unfortunately, long-term bisphosphonate use has been linked to an increased risk of atypical femoral fractures. [More]
Study debunks false reports surrounding risk of hormone therapy

Study debunks false reports surrounding risk of hormone therapy

For over a decade, hormone therapy (HT) has been a hot topic in medicine. Unfortunately, women are still confused and concerned about using HT after two federally-funded studies linked HT to potentially serious health risks. [More]
Scientists discover DNA vaccine that alleviates chronic inflammation in the body

Scientists discover DNA vaccine that alleviates chronic inflammation in the body

An international team of scientists including CureLab Oncology, Inc. (Boston), University of Camerino (Italy), and Boston University have serendipitously discovered a DNA vaccine, which systemically alleviates chronic inflammation in the body. Since osteoporosis is an inflammatory disease, preventive and therapeutic effects of the new vaccine were demonstrated on mouse models with osteoporosis. [More]
High-impact exercise improves patellar cartilage quality of postmenopausal women at risk of osteoporosis

High-impact exercise improves patellar cartilage quality of postmenopausal women at risk of osteoporosis

Progressive high-impact training improved the patellar cartilage quality of the postmenopausal women who may be at risk of osteoporosis (bone loss) as well as at risk of osteoarthritis. [More]
Postmenopausal women susceptible to bone fractures may be at increased risk for gum disease

Postmenopausal women susceptible to bone fractures may be at increased risk for gum disease

Postmenopausal women susceptible to bone fractures may also be a higher risk for gum disease, according to researchers at Case Western Reserve University School of Dental Medicine and Case/Cleveland Clinic Postmenopausal Health Collaboration. [More]
Harmless plant extract can help treat Cushing Disease

Harmless plant extract can help treat Cushing Disease

Cushing Disease, not to be confused with Cushing's Syndrome, is caused by a tumour in the pituitary gland in the brain. The tumour secrets increased amounts of the stress hormone adrenocorticotropin (ACTH) followed by cortisol release from the adrenal glands leading to rapid weight gain, elevated blood pressure and muscular weakness. [More]
Camp Twinkletoes improves lives of children suffering from juvenile arthritis

Camp Twinkletoes improves lives of children suffering from juvenile arthritis

Throughout NSW, there are more than 6,000 children suffering from the extreme pain and fatigue of juvenile arthritis. Usually thought of as an ‘older persons’ disease, arthritis in children is a very real condition, and in extreme cases can even result in death. [More]
Researchers develop new method for preventing destructive activity of osteoclasts

Researchers develop new method for preventing destructive activity of osteoclasts

Most existing treatments for pathological bone loss inhibit osteoclasts (bone-destroying cells) to limit bone degradation. However, by doing this, they also prevent bone formation since it is stimulated by the presence of these very same osteoclast cells. Researchers from the CNRS, Inserm and the Université de Montpellier and Université Jean Monnet - Saint-étienne have developed a new approach for preventing the destructive activity of osteoclasts without affecting their viability. [More]
Griffith study shows resistance training improves bone, muscle strength in post-menopausal women

Griffith study shows resistance training improves bone, muscle strength in post-menopausal women

Big improvements in strength with no injuries have been the hallmarks of success with a Griffith University study looking at the physical function of post-menopausal women. [More]
Sleep apnea may cause some cases of osteoporosis

Sleep apnea may cause some cases of osteoporosis

The daily rhythm of bone turnover is likely important for normal bone health, and recent research suggests that sleep apnea may be an unrecognized cause of some cases of osteoporosis. Sleep apnea's effects on sleep duration and quality, oxygen levels, inflammation, and other aspects of health may have a variety of impacts on bone metabolism. [More]
Exposure to certain chemicals may lead to early menopause

Exposure to certain chemicals may lead to early menopause

Women who are exposed to certain chemicals are more likely to experience menopause at a younger age, according to a newly published study by a researcher from the University of Colorado School of Medicine at the Anschutz Medical Campus. [More]
Gluten-free diet important for people with celiac disease

Gluten-free diet important for people with celiac disease

You'd never suspect it from the proliferation of gluten-free items on supermarket shelves. Yet only one in approximately 133 people - that's 0.75 percent of the population - has celiac disease, a genetic autoimmune disorder that causes the body to react negatively to the intake of gluten, a protein found in wheat, rye, barley and their derivatives. [More]
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