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Acute otitis media (AOM) is a common childhood disease with important ramifications to the overall health of infants and young children. The peak incidence of AOM occurs at 6 to 18 months of age, but it can also occur in older children. Complications of AOM include persistent middle ear effusion, chronic otitis media, transient hearing loss, or speech delays.
Researchers uncover groundbreaking evidence for developing vaccine to prevent middle ear infections

Researchers uncover groundbreaking evidence for developing vaccine to prevent middle ear infections

Researchers from Griffith University's Institute for Glycomics, together with the Nationwide Children's Hospital in Ohio, have uncovered groundbreaking evidence to help vaccine developers prevent middle ear infections. [More]
Simple procedure with nasal balloon can reduce impact of hearing loss in children

Simple procedure with nasal balloon can reduce impact of hearing loss in children

For children with a common middle-ear problem, a simple procedure with a nasal balloon can reduce the impact of hearing loss and avoid unnecessary and ineffective use of antibiotics, according to a new study led by researchers from the University of Southampton. [More]
Dr. Jian-Dong Li receives $1.6 million to develop novel therapeutic targets to treat middle-ear infections

Dr. Jian-Dong Li receives $1.6 million to develop novel therapeutic targets to treat middle-ear infections

Dr. Jian-Dong Li, a professor and director of the Institute for Biomedical Sciences at Georgia State University and a Georgia Research Alliance Eminent Scholar in Inflammation and Immunity, has received a five-year, $1.6 million federal grant to develop novel anti-inflammatory therapeutics against middle-ear infections. [More]
Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1. [More]
Existing anti-stroke drug can be effective in treating middle-ear infections

Existing anti-stroke drug can be effective in treating middle-ear infections

An existing anti-stroke drug is an effective treatment for middle-ear infections, showing the ability to suppress mucus overproduction, improve bacterial clearance and reduce hearing loss, according to researchers at Georgia State University and the University of Rochester. [More]
Second-generation antibiotic shows promise against common bacterial infections

Second-generation antibiotic shows promise against common bacterial infections

Researchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness against common bacterial infections that pose a serious health threat to children and adults. [More]
PPDC awards grants to three companies developing new medical devices for children

PPDC awards grants to three companies developing new medical devices for children

The Philadelphia Pediatric Medical Device Consortium announces its first three awards to companies developing new medical devices for children. [More]
GSU researchers discover how steroids use a novel 'trick' to suppress inflammation

GSU researchers discover how steroids use a novel 'trick' to suppress inflammation

A new "trick" steroids use to suppress inflammation, which could be used to make new anti-inflammatory drugs without the harmful side effects of steroids, has been discovered by researchers at Georgia State University. [More]
Increasing length of breastfeeding could save over £40 million annually for NHS

Increasing length of breastfeeding could save over £40 million annually for NHS

The NHS could save more than £40 million a year by increasing the length of time that mothers breastfeed, according to research carried out at Brunel University London. [More]
Influenza can cause ear and throat infections

Influenza can cause ear and throat infections

Influenza infection can enhance the ability of the bacterium Streptococcus pneumoniae to cause ear and throat infections, according to research published ahead of print in the journal Infection and Immunity. [More]
Early daycare attendance linked with greater childhood healthcare use

Early daycare attendance linked with greater childhood healthcare use

Daycare attendance in the first year of life is a risk factor for earlier respiratory infections and is associated with greater use of healthcare services in childhood, study findings show. [More]
‘No convincing evidence’ for zinc supplements to prevent otitis media

‘No convincing evidence’ for zinc supplements to prevent otitis media

There is no convincing evidence that zinc supplements reduce the risk of otitis media in children or adults, say the authors of an updated Cochrane review. [More]
Localised inflammation found in eosinophilic otitis media

Localised inflammation found in eosinophilic otitis media

Antigen-specific immunoglobulin E is produced locally in the middle ear mucosa of patients with eosinophilic otitis media, clinical research indicates. [More]
Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

Henry Ford Health System has launched a clinical trial to investigate a new drug for the treatment of tinnitus, a chronic ringing of the head or ears that affects more than 600 million people worldwide. [More]
Education campaign fails to improve guideline adherence in paediatric AOM

Education campaign fails to improve guideline adherence in paediatric AOM

Swedish researchers report that overall adherence to treatment guidelines for acute otitis media in children is good, at 70–90%, but that adherence to watchful waiting is poor. [More]
Mechanisms of recurrent bacteria AOM in children under scrutiny

Mechanisms of recurrent bacteria AOM in children under scrutiny

The immune response in young children with bacterial acute otitis media differs between individuals who are prone to such infection and those who are not, US researchers have shown. [More]
Immunoregulatory genes modulate otitis media risk

Immunoregulatory genes modulate otitis media risk

Variation in genes involved in immunity influences children’s susceptibility to developing otitis media, according to research by a US team. [More]
Pediatric viral respiratory tract infection often complicated by bacterial sinusitis

Pediatric viral respiratory tract infection often complicated by bacterial sinusitis

Nearly 1 in 10 cases of viral upper respiratory tract infections in infants and young children is complicated by acute bacterial sinusitis, often in conjunction with acute otitis media, a longitudinal cohort study has found. [More]
Rare case of tuberculous otitis media described

Rare case of tuberculous otitis media described

South Korean researchers have reported a rare case of tuberculous otitis media and say that ear tuberculosis should be considered in patients presenting with otitis media complicated by facial paralysis. [More]
Aston University tackles 'glue ear' problem with hearing test app

Aston University tackles 'glue ear' problem with hearing test app

Aston University is tackling the problem of 'glue ear' in children with a hearing test app for any concerned families. [More]
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