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Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.
Super-resolution imaging of biological specimens: an interview with Dr. Manasa Gudheti

Super-resolution imaging of biological specimens: an interview with Dr. Manasa Gudheti

Traditional light microscopy techniques such as confocal and wide-field are diffraction-limited in resolution, which is about 200 nm laterally (in xy) and 500 to 600 nm axially (in z). Features that are closer than the diffraction limit will appear blurred in the image. [More]
British Lung Foundation announces funding for IPF research

British Lung Foundation announces funding for IPF research

Britons are officially three times more likely to die of the incurable lung condition idiopathic pulmonary fibrosis (IPF), than in a road accident. Despite this, the disease is so unheard of and underfunded in research doctors still don’t know what causes it. [More]
Diet high in calcium, low in lactose may decrease risk of ovarian cancer in African-American women

Diet high in calcium, low in lactose may decrease risk of ovarian cancer in African-American women

Research from Rutgers Cancer Institute of New Jersey and and other U.S. health and academic institutions shows a diet high in calcium and low in lactose may reduce the risk of ovarian cancer in African-American women. [More]
BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

Few effective treatments have been approved to treat ovarian cancer, the deadliest of all cancers affecting the female reproductive system. [More]
Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass. [More]
New drug holds potential for treating advanced mastocytosis

New drug holds potential for treating advanced mastocytosis

Most people have never heard of mastocytosis. It's a rare, sometimes deadly, immune disorder. Now new research may help those with advanced mastocytosis and possibly many more people, too. [More]
Oral contraceptive use may be reason for decline in mortality from ovarian cancer worldwide

Oral contraceptive use may be reason for decline in mortality from ovarian cancer worldwide

Deaths from ovarian cancer fell worldwide between 2002 and 2012 and are predicted to continue to decline in the USA, European Union and, though to a smaller degree, in Japan by 2020, according to new research published in the leading cancer journal Annals of Oncology today (Tuesday). [More]
DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors. [More]
New NCCN Imaging AUC released for eight new cancers

New NCCN Imaging AUC released for eight new cancers

The National Comprehensive Cancer Network, a Centers for Medicare & Medicaid Services-approved provider-led entity for imaging appropriate use criteria, continues to build its library of AUC and has published NCCN Imaging Appropriate Use Criteria for eight new cancer types. Launched in June 2016, NCCN Imaging AUC currently are available for 20 cancer types. [More]
New drug delivery system slows and controls tumors not aiming for complete elimination

New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination. [More]
SGO and ASCO release clinical practice guidelines on ovarian cancer treatment

SGO and ASCO release clinical practice guidelines on ovarian cancer treatment

This week the Society of Gynecologic Oncology and the American Society of Clinical Oncology issued a joint clinical practice guideline on ovarian cancer treatment. [More]
Researchers develop computational algorithm to analyze big genomic data for different cancers

Researchers develop computational algorithm to analyze big genomic data for different cancers

University of Hawai'i Cancer Center researchers developed a computational algorithm to analyze "Big Data" obtained from tumor samples to better understand and treat cancer. [More]
People diagnosed with bowel cancer under 50 not tested for Lynch syndrome, research finds

People diagnosed with bowel cancer under 50 not tested for Lynch syndrome, research finds

The UK’s leading bowel cancer research charity, Bowel Cancer UK, and the Royal College of Pathologists have today published findings which show that people under 50 diagnosed with bowel cancer are not being tested for Lynch syndrome – a genetic condition that increases the risk of bowel cancer by 80 per cent. [More]
Higher socioeconomic status linked to lower ovarian cancer risk in African American women

Higher socioeconomic status linked to lower ovarian cancer risk in African American women

Higher socioeconomic status (SES) is associated with lower ovarian cancer risk in African American women, according to the results of a study by investigators at the Medical University of South Carolina and elsewhere reported online August 3 by the American Journal of Epidemiology. [More]
Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%. [More]
Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer Junghae Suh has been awarded a prestigious R01 grant by the National Institutes of Health to research the use of viral gene therapy to fight ovarian cancer. [More]
Bio-Rad expands product line by launching two human recombinant antigens

Bio-Rad expands product line by launching two human recombinant antigens

Bio-Rad Laboratories, Inc., a global provider of life science research and clinical diagnostic products, today announced the launch of two human recombinant antigens, expanding the company's portfolio of Critical Raw Materials for the in vitro diagnostics market. [More]

Collaborative effort to assist injured women with ovarian cancer from talc-based Baby Powder

Greg Vigna, MD, JD, founder of Life Care Solutions Group and Jane Akre, founder of Mesh Medical Device News Desk today launch a collaborative effort to educate, empower, and assist catastrophically injured women with ovarian cancer, who were exposed to Johnson & Johnson Baby Powder containing Talc. [More]
T-cell technology could be used to treat ovarian tumors with no adverse effects

T-cell technology could be used to treat ovarian tumors with no adverse effects

With only incremental improvements in ovarian cancer survival over the last 40 years, there is a clear need for new treatment options with long-lasting results. Many researchers have turned toward the development of immunotherapies that direct T-cells to selectively eliminate ovarian tumor cells, but an appropriate therapeutic target for ovarian cancers has remained elusive. [More]
Researchers develop tiny 3-D tissue models to study how ovarian cancer develops in women

Researchers develop tiny 3-D tissue models to study how ovarian cancer develops in women

With a unique approach that draws on 3-D printing technologies, a team of University of Wisconsin-Madison researchers is developing new tools for understanding how ovarian cancer develops in women. [More]
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