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Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.
New drug delivery system slows and controls tumors not aiming for complete elimination

New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination. [More]
SGO and ASCO release clinical practice guidelines on ovarian cancer treatment

SGO and ASCO release clinical practice guidelines on ovarian cancer treatment

This week the Society of Gynecologic Oncology and the American Society of Clinical Oncology issued a joint clinical practice guideline on ovarian cancer treatment. [More]
Researchers develop computational algorithm to analyze big genomic data for different cancers

Researchers develop computational algorithm to analyze big genomic data for different cancers

University of Hawai'i Cancer Center researchers developed a computational algorithm to analyze "Big Data" obtained from tumor samples to better understand and treat cancer. [More]
People diagnosed with bowel cancer under 50 not tested for Lynch syndrome, research finds

People diagnosed with bowel cancer under 50 not tested for Lynch syndrome, research finds

The UK’s leading bowel cancer research charity, Bowel Cancer UK, and the Royal College of Pathologists have today published findings which show that people under 50 diagnosed with bowel cancer are not being tested for Lynch syndrome – a genetic condition that increases the risk of bowel cancer by 80 per cent. [More]
Higher socioeconomic status linked to lower ovarian cancer risk in African American women

Higher socioeconomic status linked to lower ovarian cancer risk in African American women

Higher socioeconomic status (SES) is associated with lower ovarian cancer risk in African American women, according to the results of a study by investigators at the Medical University of South Carolina and elsewhere reported online August 3 by the American Journal of Epidemiology. [More]
Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%. [More]
Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer Junghae Suh has been awarded a prestigious R01 grant by the National Institutes of Health to research the use of viral gene therapy to fight ovarian cancer. [More]
Bio-Rad expands product line by launching two human recombinant antigens

Bio-Rad expands product line by launching two human recombinant antigens

Bio-Rad Laboratories, Inc., a global provider of life science research and clinical diagnostic products, today announced the launch of two human recombinant antigens, expanding the company's portfolio of Critical Raw Materials for the in vitro diagnostics market. [More]

Collaborative effort to assist injured women with ovarian cancer from talc-based Baby Powder

Greg Vigna, MD, JD, founder of Life Care Solutions Group and Jane Akre, founder of Mesh Medical Device News Desk today launch a collaborative effort to educate, empower, and assist catastrophically injured women with ovarian cancer, who were exposed to Johnson & Johnson Baby Powder containing Talc. [More]
T-cell technology could be used to treat ovarian tumors with no adverse effects

T-cell technology could be used to treat ovarian tumors with no adverse effects

With only incremental improvements in ovarian cancer survival over the last 40 years, there is a clear need for new treatment options with long-lasting results. Many researchers have turned toward the development of immunotherapies that direct T-cells to selectively eliminate ovarian tumor cells, but an appropriate therapeutic target for ovarian cancers has remained elusive. [More]
Researchers develop tiny 3-D tissue models to study how ovarian cancer develops in women

Researchers develop tiny 3-D tissue models to study how ovarian cancer develops in women

With a unique approach that draws on 3-D printing technologies, a team of University of Wisconsin-Madison researchers is developing new tools for understanding how ovarian cancer develops in women. [More]
Study uncovers new drug-gene mutation combinations that can kill cancer cells

Study uncovers new drug-gene mutation combinations that can kill cancer cells

In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells. [More]
Scientists find promising new method to detect and treat recurrence of ovarian cancer

Scientists find promising new method to detect and treat recurrence of ovarian cancer

Researchers at the Mayo Clinic Center for Individualized Medicine have found a promising new way to monitor and treat recurrence of ovarian cancer -- a hard-to-detect disease that claims many lives. [More]
New streamlined approach to genetic testing benefits women with ovarian cancer

New streamlined approach to genetic testing benefits women with ovarian cancer

A new streamlined approach to genetic testing for women with ovarian cancer provides testing rapidly and affordably, allowing many more patients to benefit from personalised cancer management and their relatives to benefit from cancer prevention strategies. [More]
Study shows feasibility to adopt salpingectomy in large scale clinical practice without surgical repercussions

Study shows feasibility to adopt salpingectomy in large scale clinical practice without surgical repercussions

A surgical procedure recommended to reduce the future risk of ovarian cancer has been successfully implemented throughout Kaiser Permanente in Northern California without a change in surgical outcomes, according to research published today in the journal Obstetrics & Gynecology. [More]
Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Like pancreatic cancer, cancer of the ovaries is notorious for being discovered at a relatively late stage - after it has spread to other sites in the body. It is not called "the silent killer" for nothing. [More]
Inherited mutations in DNA repair genes may predispose to metastatic prostate cancer

Inherited mutations in DNA repair genes may predispose to metastatic prostate cancer

Inherited mutations in genes that function to repair DNA may contribute to metastatic prostate cancer more than previously recognized, according to a study out today in the New England Journal of Medicine. [More]
Women with BRCA1 gene mutation at increased risk of aggressive uterine cancer

Women with BRCA1 gene mutation at increased risk of aggressive uterine cancer

Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a study led by a Duke Cancer Institute researcher. [More]
Online information can increase feelings of worry and fear among women at risk of ovarian cancer

Online information can increase feelings of worry and fear among women at risk of ovarian cancer

Researchers at Cardiff University have found that online information about ovarian cancer can cause as much worry as comfort for women at high risk of developing the disease, in a new study published in ecancer. [More]
Study focuses on critical proteins involved in ovarian cancer biology

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors. [More]
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