Ovarian Cancer News and Research RSS Feed - Ovarian Cancer News and Research Twitter

Commonly known as the "silent killer," ovarian cancer leads to approximately 15,000 deaths each year in the United States, according to the American Cancer Society. Approximately 20,000 new cases are diagnosed each year, with the majority in patients diagnosed with late stage disease where the cancer has spread beyond the ovary. The prognosis is poor in these patients, leading to the high mortality from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ovarian cancer versus those with low risk, as well as a screening test for the diagnosis of early-stage ovarian cancer, which is essential for improving overall survival in patients. Ovarian cancer has up to a 90% cure rate following surgery and/or chemotherapy if detected in stage 1.
Boehringer Ingelheim to highlight respiratory research work at ATS 2013

Boehringer Ingelheim to highlight respiratory research work at ATS 2013

Boehringer Ingelheim will contribute to advancing the scientific discussion in respiratory disease at the American Thoracic Society International Conference in Philadelphia, PA, May 17 – 22. [More]

Women with family history of cancer need to have proper counseling, testing

In the wake of actress Angelina Jolie's public announcement that she recently underwent a preventive double mastectomy, Loma Linda University Medical Center urges women with a family history of cancer to have proper counseling and testing, if indicated, to see if they are at similar risk. [More]
NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Northwest Biotherapeutics, a biotechnology company developing DCVax-L personalized immune therapies for solid tumor cancers, today announced that its Phase III clinical trial with DCVax-L for brain cancer has been initiated at King's College Hospital in the UK. [More]

Viewpoints: Controversy taints IRS efforts on health law; Another chance to 'gut' the overhaul in the courts; Salt wrongly accused

Even as the politicized tax enforcement scandal expands, the Internal Revenue Service continues to expand its political powers thanks to the Affordable Care Act. A larger government always creates more openings for abuse, as Americans will learn when the IRS starts auditing their health care in addition to their 1040 next year (5/14). [More]
Study underscores new paradigm in cancer therapy

Study underscores new paradigm in cancer therapy

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers. [More]
UAB genetics and breast cancer experts respond to Angelina Jolie's preventive mastectomy

UAB genetics and breast cancer experts respond to Angelina Jolie's preventive mastectomy

Hollywood actress Angelina Jolie, who has one of the genes linked to breast cancer, revealed that she underwent a double mastectomy earlier this year to prevent following in the footsteps of her mother and succumbing to breast cancer. [More]
Viewpoints: Angelina Jolie on her decision to have a double mastectomy; Justice Ginsburg's 'blind spot' on abortion

Viewpoints: Angelina Jolie on her decision to have a double mastectomy; Justice Ginsburg's 'blind spot' on abortion

My doctors estimated that I had an 87 percent risk of breast cancer and a 50 percent risk of ovarian cancer, although the risk is different in the case of each woman. Only a fraction of breast cancers result from an inherited gene mutation. Those with a defect in BRCA1 have a 65 percent risk of getting it, on average. Once I knew that this was my reality, I decided to be proactive and to minimize the risk as much I could. I made a decision to have a preventive double mastectomy. I started with the breasts, as my risk of breast cancer is higher than my risk of ovarian cancer, and the surgery is more complex (Angelina Jolie, 5/14). [More]
USF, Aetna to examine influence of genetic testing on breast cancer treatment

USF, Aetna to examine influence of genetic testing on breast cancer treatment

The University of South Florida and Aetna are launching a ground-breaking study that will examine the influence genetic testing may have on clinical treatment decisions among breast cancer patients and their doctors. [More]

Precision Therapeutics to present clinical data of ChemoFx chemoresponse assay at WAGO meeting

Precision Therapeutics, Inc., a life science company that develops personalized medicine products for individualizing cancer care, today announced that a clinical study which demonstrates the feasibility of the ChemoFx chemoresponse assay to identify patients unlikely to respond to first-line therapy has been accepted for presentation at the 2013 Annual Meeting of the Western Association of Gynecologic Oncologists. [More]
Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body. [More]
Entremed reports patent issuance for its lead drug candidate ENMD-2076

Entremed reports patent issuance for its lead drug candidate ENMD-2076

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, today announced the issuance by the Chinese State Intellectual Property Office of Patent Certificate No. ZL 200680044656.7. [More]
Mutations in phosphatase Wip1 could be a new target for treating cancer

Mutations in phosphatase Wip1 could be a new target for treating cancer

Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers. [More]
EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, announced the issuance of a U.S. patent covering methods of treatment and formulations for its clinical-stage compound, 2-methoxyestradiol. [More]
Variations in the sequencing of TERT gene influence risk of breast, ovarian cancers

Variations in the sequencing of TERT gene influence risk of breast, ovarian cancers

A major international study involving a Simon Fraser University scientist has found that sequence differences in a gene crucial to the maintenance of our chromosomes' integrity predispose us to certain cancers. [More]
Powerful data-sifting algorithms help untangle complex genetics of cancer

Powerful data-sifting algorithms help untangle complex genetics of cancer

Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. [More]
Genomics-based testing could change recommended course of treatment for endometrial cancer

Genomics-based testing could change recommended course of treatment for endometrial cancer

The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women. [More]
Details about genomic landscapes of AML and endometrial cancer revealed

Details about genomic landscapes of AML and endometrial cancer revealed

Two studies from The Cancer Genome Atlas program reveal details about the genomic landscapes of acute myeloid leukemia and endometrial cancer. [More]

Researchers discover gene that can cause 3 different diseases depending on its alteration

An international research consortium led by the Universitat Aut-noma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending on how it is altered. [More]

Study shows chemoresponse assay improves survival rates in women with ovarian cancer

This spring, a team of researchers has released results from an eight-year study that shows improved survival rates for women diagnosed with ovarian cancer who undergo cancer tumor testing to determine the best treatment. [More]
New screening method detects ovarian cancer by examining neighboring cells

New screening method detects ovarian cancer by examining neighboring cells

Pioneering biophotonics technology developed at Northwestern University is the first screening method to detect the early presence of ovarian cancer in humans by examining cells easily brushed from the neighboring cervix or uterus, not the ovaries themselves. [More]