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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.
ANK3 and other genes may play key role in affecting mood, stress and longevity

ANK3 and other genes may play key role in affecting mood, stress and longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research. [More]
Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition. [More]
Consuming sesame-based ingredients may reduce oxidative stress

Consuming sesame-based ingredients may reduce oxidative stress

The antioxidant boosting properties of sesame, and especially sesame oil, can have a significant effect on oxidative stress, improving human health, according to a systematic review published in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
New study links altered purine metabolism to major depressive disorder

New study links altered purine metabolism to major depressive disorder

People suffering from major depressive disorder may have altered purine metabolism, according to a new study from the University of Eastern Finland and Kuopio University Hospital. [More]
TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

In a pair of related studies, chemists from the Florida campus of The Scripps Research Institute (TSRI) have identified and designed dozens of molecular “warheads” that not only can detect a key biomarker of cancer, but also could be developed into a potent new class of drug candidates for a range of diseases. [More]
Major breakthrough in understanding impact of oxygen exposure on aging process

Major breakthrough in understanding impact of oxygen exposure on aging process

A study published in the US journal, Aging by the University of Surrey and University of Rochester has made an important breakthrough in understanding the impact of oxygen exposure on the aging process of mammal cells. [More]
Titanium dioxide nanoparticles can have low-level effects on oxidative stress genes

Titanium dioxide nanoparticles can have low-level effects on oxidative stress genes

A nanoparticle commonly used in food, cosmetics, sunscreen and other products can have subtle effects on the activity of genes expressing enzymes that address oxidative stress inside two types of cells. [More]
Blueberry component PS may protect against dry eye disease

Blueberry component PS may protect against dry eye disease

Pterostilbene (PS), a component of blueberries, have been found to protect against dry eye disease according to a new study. [More]
Low levels of vitamin D, methylation in black teens may increase cancer risk

Low levels of vitamin D, methylation in black teens may increase cancer risk

Low levels of vitamin D in black teens correlates with low activity of a major mechanism for controlling gene expression that may increase their risk of cancer and other disease, researchers report. [More]
New computer algorithm can better characterize functional context of genomic variations in cancer

New computer algorithm can better characterize functional context of genomic variations in cancer

Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the combinations of which can be unique to each individual patient. [More]
Scientists discover underlying mechanisms of nerve damage

Scientists discover underlying mechanisms of nerve damage

Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the treatment of this condition, which causes pain, numbness and/or tingling in the hands and feet. The research was published March 28 in the Proceedings of the National Academy of Sciences. [More]
Increased expression of VEGF-A promotes three common aging-related eye conditions

Increased expression of VEGF-A promotes three common aging-related eye conditions

A Massachusetts General Hospital investigator has found that increased expression of the angiogenic factor VEGF-A promotes three common aging-related eye conditions - both versions of age-related macular degeneration (AMD) and also cataracts - in an animal model. [More]
Novel metabolic pathways help cancer cells thrive under certain conditions

Novel metabolic pathways help cancer cells thrive under certain conditions

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have identified a novel metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal cells. [More]
Aged tumor cells in melanoma behave in a different way than younger tumor cells

Aged tumor cells in melanoma behave in a different way than younger tumor cells

Cancer risk increases with one's age as accumulated damage to our cells and chronic inflammation occur over time. Now, an international team of scientists led by The Wistar Institute have shown that aged tumor cells in melanoma behave differently than younger tumor cells, according to study results published in the journal Nature. [More]
Tumor suppressor p53 gene twice as likely to be defective in autistic children

Tumor suppressor p53 gene twice as likely to be defective in autistic children

A large study by researchers with the UC Davis MIND Institute has found that a gene whose role is to suppress cellular damage from environmental stressors is nearly twice as likely to be defective in children with autism spectrum disorder (ASD), and that the deficit is also present in their fathers. [More]
New Rutgers study links protein that helps fight infection to heart and liver disease

New Rutgers study links protein that helps fight infection to heart and liver disease

A protein that should help fight infection and keep us healthy may be targeted for treating devastating illnesses like heart and liver disease, according to a new Rutgers study. [More]
Long-term recreational football training improves health of older men

Long-term recreational football training improves health of older men

A new scientific study shows that long-term recreational football training produces a number of marked improvements in health profile for 63-75 year old untrained men -- including a reduced risk of developing cardiovascular diseases and diabetes. [More]
Enhanced diet helps slow progression of hereditary deafness

Enhanced diet helps slow progression of hereditary deafness

An enhanced diet helped reduce hearing loss in mice with the genetic mutation most commonly responsible for childhood deafness, new research suggests. [More]
Depression may be a systemic disease, say researchers

Depression may be a systemic disease, say researchers

An international team of researchers lead by the University of Granada has scientifically proven, for the first time, that depression is associated with important alterations of the oxidative stress, so it should be considered a systemic disease. [More]
Researchers develop effective technique for studying high-arched palate using mouse model

Researchers develop effective technique for studying high-arched palate using mouse model

Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality. [More]
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