Pandemic News and Research

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A pandemic is a global disease outbreak. During a pandemic, transmission can be anticipated in the workplace, not only from patient to workers in health care settings, but also among co-workers in general work settings. A pandemic would cause high levels of illness, death, social disruption, and economic loss. Everyday life would be disrupted because so many people in so many places become seriously ill at the same time. Impacts could range from school and business closings to the interruption of basic services such as public transportation and food delivery.

The potential global risk of monkeypox importation

Researchers hypothesized various scenarios of travel restrictions to estimate the potential global risk of monkeypox virus (MPXV) importation.

21 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Covid still kills, but the demographics of its victims are shifting

As California settles into a third year of pandemic, covid-19 continues to pose a serious threat of death. But the number of people dying — and the demographics of those falling victim — has shifted notably from the first two years.

21 Sep 2022

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

The present study reported the development of a new self-assembled trimeric RBD subunit vaccine that could effectively prevent infection from SARS-CoV-2 variants, including the currently dominantly circulating Omicron variant.

21 Sep 2022

Study reveals improved immunogenicity and safety of bivalent Omicron-containing mRNA-1273.214 candidate booster vaccine

In a new study, a team of researchers assessed the safety and efficacy of a bivalent candidate vaccine containing spike messenger ribonucleic acids of the ancestral Wuhan-Hu-1 strain and the Omicron B.1.1.529 [BA.1] variant of SARS-CoV-2.

21 Sep 2022

World Alzheimer’s Day 2022: Improving Post-Diagnosis Care with COGNISANCE

To commemorate World Alzheimer's Day, News-Medical speaks to Dr. Meredith Gresham, coordinator of COGNISANCE: Co-Designing Dementia Diagnosis And Post Diagnostic Care, about the project and post-dementia diagnosis care for patients and their families.

21 Sep 2022

Study shows COVID-19 activity peaks during winter in the United States and Europe

In a recent study posted to the Research Square* preprint server, researchers from Columbia University Mailman School of Public Health, Pfizer Inc, and the University of Iowa assessed the seasonal trends observed in coronavirus disease 2019 (COVID-19) cases, hospitalizations, and deaths.

21 Sep 2022

Study: Life-threatening blood clots remain for at least 49 weeks after COVID-19

COVID-19 infection increases the risk of potentially life-threatening blood clots for at least 49 weeks, according to a new study of health records of 48 million unvaccinated adults from the first wave of the pandemic.

21 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Mohsan Saeed, PhD, assistant professor of biochemistry at Boston University School of Medicine (BUSM), has received a five-year, $2 million R35 grant from the National Institute of General Medical Sciences, as well as a five-year, $2.5 million R01 grant from the National Institute of Allergy and Infectious Diseases.

20 Sep 2022

Healthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year

In a new study, researchers conducted a community-based prospective cohort study in Managua, Nicaragua, before the winter season when influenza A (H3N2) cases surge in the Northern Hemisphere.

20 Sep 2022

What is the SARS-CoV-2 transmissibility among United States residents?

In a new study, researchers estimated region-specific basic reproduction number (R0) values for metropolitan statistical areas in the US, based on compartmental modeling with reproduced SARS-CoV-2 surveillance data.

20 Sep 2022

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

A recent study assessed the dynamic trajectory of COVID-19 symptom burden as well as symptom persistence in those who survived SARS-CoV-2 infection for two years after being discharged from hospitals.

20 Sep 2022

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Researchers investigated nanobody engineering to develop antivirals and diagnostic tools against SARS-CoV-2.

20 Sep 2022

Endogenous exosomes act as decoys for SARS-CoV-2

A recent study published in the journal PLoS Biology discussed exosomes as potential decoys for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Sep 2022

COVID-19 during pregnancy damages the placenta's immune response to further infections

If a woman contracts COVID-19 during her pregnancy, the infection, even if it's mild, damages the placenta's immune response to further infections, a UW Medicine-led study has found.

19 Sep 2022

Study estimates 18 million Americans have long-COVID

In a recent study posted to the medRxiv* preprint server, researchers evaluated the prevalence, risk factors, and impact of post-coronavirus disease (COVID) conditions (PCC) or long COVID on daily activities among adults residing in the United States (US).

19 Sep 2022

Study provides an update on depression prevalence among the U.S. population

Increases in depression without commensurate increases in treatment are widespread, reports a study conducted at Columbia University Mailman School of Public Health and City University of New York.

19 Sep 2022

Collective stressors may set young adults on a less fortunate path

2020 was a uniquely stressful year - with the onset of the COVID-19 pandemic, the murder of George Floyd, and a contentious presidential election in the United States.

19 Sep 2022

Pandemic News and Research

Further Reading

The potential global risk of monkeypox importation

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Common genetic variants of APOE associated with COVID mortality

Covid still kills, but the demographics of its victims are shifting

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

Study reveals improved immunogenicity and safety of bivalent Omicron-containing mRNA-1273.214 candidate booster vaccine

World Alzheimer’s Day 2022: Improving Post-Diagnosis Care with COGNISANCE

Study shows COVID-19 activity peaks during winter in the United States and Europe

Study: Life-threatening blood clots remain for at least 49 weeks after COVID-19

SARS-CoV-2 generates amyloid in cerebral spinal fluid

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Healthcare systems seem may be ill-equipped to handle high co-circulation of influenza and SARS-CoV-2 in the coming year

What is the SARS-CoV-2 transmissibility among United States residents?

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Endogenous exosomes act as decoys for SARS-CoV-2

COVID-19 during pregnancy damages the placenta's immune response to further infections

Study estimates 18 million Americans have long-COVID

Study provides an update on depression prevalence among the U.S. population

Collective stressors may set young adults on a less fortunate path

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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