Pandemrix News and Research

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Are nasal-spray vaccines the solution to respiratory infectious diseases?

A recent study published in the journal Trends in Molecular Medicine reviewed the current efforts in developing nasal vaccines, delivery systems, and clinical applications for preventing respiratory illnesses.

28 Nov 2022

New discovery increases understanding of the effects of narcolepsy on the brain

Narcolepsy alters the pulsations that maintain the brain’s waste clearance system, shows a new study from the University of Oulu. The researchers’ discovery increases our understanding of the effects of narcolepsy on the brain, and may also help in the diagnosis of the disease.

21 Nov 2022

Study uncovers a novel autoantigen in patients with narcolepsy type 1

Researchers at the University of Helsinki have identified influenza virus peptides that resemble human protein fragments and can cause an immune response against the body’s own cells due to cross-reactivity.

26 Apr 2021

Study shows no relation between swine flu vaccination and increased risk of type 1 diabetes

There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk of autoimmune diseases other than narcolepsy.

9 Oct 2017

Swedish study confirms H1N1 vaccinations show increased risk of narcolepsy in children, adolescents

Pandemrix is an influenza vaccination, created in 2009 to combat H1N1, known as Swine Flu. Now, a team of Swedish clinicians testing the vaccine for links to immune-related or neurological diseases have linked Pandemrix to an increased risk of narcolepsy in young adults.

21 Jan 2014

Parents blame swine flu vaccine for son’s narcolepsy

A six year old boy’s parents have claimed that he developed narcolepsy after a swine flu vaccination. Caroline Hadfield said son Josh lost muscle control and started sleeping up to 19 hours a day three weeks after being given Pandemrix nearly two years ago.

12 Dec 2011

Finland national health institute finds link between H1N1 flu vaccine and children's narcolepsy

"Finland's national health institute said on Thursday its latest research on previously found links between children's narcolepsy and GlaxoSmithKline's Pandemrix vaccine against H1N1 swine flu also involved a genetic risk factor," Reuters reports.

3 Sep 2011

Narcolepsy more prevalent in China during April

New research shows that the occurrence of narcolepsy in China is highly correlated to a seasonal pattern, with onset most frequent in April.

22 Aug 2011

Winter airway infections appear to trigger narcolepsy: Study

The onset of narcolepsy appears to follow seasonal patterns of H1N1 and other upper airway infections, according to a new study of patients in China that was led by Stanford University School of Medicine narcolepsy expert Emmanuel Mignot, MD.

22 Aug 2011

EMA says link between narcolepsy and Pandemrix 2009 H1N1 vaccine exists

A final review result from Europe's drug regulatory agency released a positive link between narcolepsy and the Pandemrix 2009 H1N1 vaccine. The agency recommends a labeling change that limits the vaccine's use in children and teens to when protection is needed and seasonal trivalent vaccine isn't available.

21 Jul 2011

Swine flu vaccine and risk of Guillain-Barré Syndrome

In a large five nation study from Europe it was seen that the use of adjuvanted vaccines against the pandemic H1N1 influenza virus probably did not increase the risk of Guillain-Barré Syndrome (GBS), but the investigators could not firmly rule out a slightly greater chance of suffering the paralytic condition.

13 Jul 2011

New report shows 2% decrease in anxiolytic and hypnotic sales in Norway

After many years of gradual increase followed by a three-year levelling off period, sales of addictive anxiolytic and hypnotic drugs decreased by just under two per cent in 2010.

24 Mar 2011

Flu vaccine update

This new vaccine which could become available in the United States in the next few years, is made by growing the influenza virus in cultures of animal cells rather than in the chicken eggs that have been used for more than five decades. This shortens the process by six months. Using animal cells, which are grown in enclosed steel tanks, also reduces the risk of bacterial contamination, which has led to shortages of seasonal vaccines in some years. The study was reported in The Lancet this Tuesday.

16 Feb 2011

Swine flu shots linked to narcolepsy: Investigation continues

The vaccine used against swine flu has been linked to a disorder called narcolepsy among those aged four to 19. Narcolepsy involves people falling asleep without warning or sleeping excessively in the daytime. A preliminary study also “observed [an] increase in incidence of narcolepsy” among those given the vaccine.

2 Feb 2011

Old flu jabs from pandemic to combat this winter’s peak

With rise of incidence of flu this winter emergency stocks of the vaccine are being released. A review is to be carried out into whether vaccines should be purchased centrally next year in order to avoid shortages. At present the GPs can procure the jabs directly from manufacturers according to their estimates of patient requirement.

9 Jan 2011

Has the NHS procured too many swine flu shots?

Britain’s National Health Service (NHS) has nearly 34 million unused swine flu vaccines at present due to a drop in the number of cases and these vaccinations. A total 44 million shots were procured. 3.8 million of these unused shots will be sent to Africa via the World Health Organization to help them. Of the rest, 10.6m is already with GPs who will be ready to act if more people entitled to the jab come forward. But the remaining 23.6m will be held in reserve.

7 Apr 2010

GSK initiates major seasonal influenza vaccine efficacy trial

GlaxoSmithKline (GSK) announced today that it has started a worldwide clinical efficacy trial to evaluate an innovative vaccine for the prevention of seasonal influenza.

6 Nov 2008