Parathyroidectomy News and Research

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$Primary hyperparathyroidism increases patients' risk of hip fracture, heart attack and stroke$

Primary hyperparathyroidism increases patients' risk of hip fracture, heart attack and stroke

In the hormonal disorder primary hyperparathyroidism, patients' risk of hip fracture is elevated by 51%, and that of heart attack or stroke 45%.

16 Jun 2022

FDA authorizes two devices that provide real-time location of parathyroid tissue during surgery

Today, the U.S. Food and Drug Administration permitted marketing of two devices that provide real-time location of parathyroid tissue during surgical procedures such as thyroidectomy (surgery to remove all or part of the thyroid) and parathyroidectomy (surgery to remove one or more parathyroid glands).

2 Nov 2018

Study shows spillover effect of evidence-based opioid prescribing for major procedures

To curb the use of opioids after major elective operations and prevent these pain relievers from falling into the wrong hands, surgeons at the University of Michigan developed prescribing recommendations based on published medical evidence for one operation, gall bladder removal, and then discovered a spillover effect that led them to prescribe roughly 10,000 fewer pills for other major operations, according to study results appearing as an "article in press" on the website of the Journal of the American College of Surgeons ahead of print.

27 Jul 2018

New prognostic tool accurately predicts recurrence of parathyroid cancer

A newly-created prognostic tool reliably predicts the recurrence of parathyroid cancer, enabling physicians to identify patients at the highest risk.

28 Apr 2017

Surgery more effective than drug therapy in patients with tertiary hyperparathyroidism

A study led by researchers from the Nephrology group at Bellvitge Biomedical Research Institute (IDIBELL) and the University Hospital of Bellvitge (HUB), compared the results of surgery with drug therapy in patients with tertiary hyperparathyroidism, ie after a kidney transplant.

17 Dec 2015

Amgen announces MAA submission to EMA for novel calcimimetic agent etelcalcetide

Amgen today announced the submission of a Marketing Authorization Application (MAA) to the European Medicines Agency via the centralized procedure for etelcalcetide (formerly AMG 416) for the treatment of secondary hyperparathyroidism (SHPT) in adult patients with chronic kidney disease (CKD) on hemodialysis therapy. If approved, etelcalcetide will be the first calcimimetic agent that can be administered intravenously.

3 Sep 2015

Study explores advantages of minimally invasive parathyroidectomy for treating hyperparathyroidism

An open surgical procedure called bilateral neck exploration has been the gold standard operation for treating patients with primary hyperparathyroidism. But the development of a minimally invasive procedure to remove the parathyroid gland now offers a new option.

17 Oct 2013

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

Amgen today announced top-line results of the Phase 3 EVOLVE (EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events) trial, which evaluated Sensipar/Mimpara (cinacalcet) for the reduction of the risk of mortality and cardiovascular (CV) events among 3,883 patients with secondary hyperparathyroidism (HPT) and chronic kidney disease (CKD) receiving dialysis.

8 Jun 2012

One-side parathyroid surgery has poorer long-term outcomes

Dr James Norman, MD and his partners at the Norman Parathyroid Center have published a landmark study in this week's Journal of the American College of Surgeons describing how the operation they developed and advocated for more than 19 years has significantly poorer long-term outcomes. The unilateral or "one-side" parathyroid surgical procedure to remove parathyroid tumors from patients suffering from hyperparathyroidism is a dramatic change from the large neck operation that it replaced.

29 Mar 2012

Living-donor parathyroid gland transplant allows young woman to forgo 60 pills per day

Surgeons at the University of Illinois Hospital & Health Sciences System performed a rare living-donor parathyroid gland transplant to help a 22-year-old woman maintain normal calcium levels without the need for high-dose supplementation.

13 Mar 2012

ADVANCE study provides new insights into the management of SHPT in CKD patients

Results from the ADVANCE study presented in a late breaking clinical trial session at the ERA-EDTA 2010 Congress provide new insights into the management of secondary hyperparathyroidism in chronic kidney disease patients. ADVANCE (A randomiseD VAscular calcificatioN study to evaluate the effects of CinacalcEt) is a randomised, controlled open label study to evaluate the effects of treatment with Mimpara (cinacalcet) plus low-dose vitamin D, compared to flexible doses of vitamin D alone, on the progression of vascular and valvular calcification in dialysis patients with SHPT.

28 Jun 2010

Minimally invasive parathyroidectomy under local/sedation

Parathyroidectomy is the removal of one or more of the parathyroid glands to treat hyperparathyroidism (abnormal over-functioning of the parathyroid glands).

18 Sep 2007

Dialysis patients may be overmedicated

Changes in a widely used assay (blood test) for parathyroid hormone (PTH) have made its use with the established guidelines for end stage renal disease clinical management both inappropriate and potentially harmful to patients. This research is published in the journal Seminars in Dialysis.

5 Dec 2005