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Parkinson's disease is a brain disorder. It occurs when certain nerve cells (neurons) in a part of the brain called the substantia nigra die or become impaired. When approximately 80 percent of neurons are damaged, the symptoms of Parkinson's disease appear. Parkinson's disease affects 1 in 100 people over the age of 60, with the average age of onset being 60 years. The risk of developing Parkinson's disease increases with age. In the United States, it is estimated that 60,000 new cases of Parkinson's disease are diagnosed each year, with 1.5 million Americans currently living with the disease.
Monitoring pulse regularly after stroke helps prevent next stroke

Monitoring pulse regularly after stroke helps prevent next stroke

New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of having a second stroke. [More]
Study explores how changes in dopamine transporter function linked to brain disorders

Study explores how changes in dopamine transporter function linked to brain disorders

Recent published research in the Journal of Clinical Investigation demonstrates how changes in dopamine signaling and dopamine transporter function are linked to neurological and psychiatric diseases, including early-onset Parkinsonism and attention deficit hyperactivity disorder (ADHD). [More]

Researchers identify molecular mechanisms of cognitive decline using high-throughput proteomics

From telephone numbers to foreign vocabulary, our brains hold a seemingly endless supply of information. However, as we are getting older, our ability to learn and remember new things declines. [More]
Signs and symptoms of Lewy body dementia

Signs and symptoms of Lewy body dementia

"I watched my husband experience a decline in cognition followed by a period of what seemed like improved function only to plunge again into confusion with more frequent hallucinations," says one caregiver newly acquainted with Lewy body dementia (LBD). [More]
Researchers explore brain estrogens to mitigate learning and memory problems

Researchers explore brain estrogens to mitigate learning and memory problems

New studies being launched by neurobiologist Luke Remage-Healey at the University of Massachusetts Amherst will investigate how estrogens produced in the brains of young birds enhance their ability to learn songs during a critical window during development. [More]
Parkinson's patients that respond favorably to sham surgery express distinct neurological profile

Parkinson's patients that respond favorably to sham surgery express distinct neurological profile

Parkinson's disease is the second most common neurological disorder, affecting almost 10 million people worldwide. [More]
Brain network measures placebo effects in Parkinson's disease patients

Brain network measures placebo effects in Parkinson's disease patients

Investigators at The Feinstein Institute for Medical Research have utilized a new image-based strategy to identify and measure placebo effects in randomized clinical trials for brain disorders. The findings are published in the August issue of The Journal of Clinical Investigation. [More]
Findings fuel idea that processes of active movement and sensory processing are connected

Findings fuel idea that processes of active movement and sensory processing are connected

A new study by researchers at the University of Oregon published today in the journal Neuron describes a brainstem circuit in mice that may help explain how active movement impacts the way the brain processes sensory information. [More]
Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

There is an increasing interest in Parkinson's disease (PD) treatment by increasing dopamine content and reducing dopaminergic metabolites in the brain. [More]
People with mild traumatic brain injury may have brain damage and memory problems

People with mild traumatic brain injury may have brain damage and memory problems

Even mild traumatic brain injury may cause brain damage and thinking and memory problems, according to a study published in the July 16, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Study demonstrates that Parkinson's patients are more creative than their healthy peers

Study demonstrates that Parkinson's patients are more creative than their healthy peers

Prof. Rivka Inzelberg of Tel Aviv University's Sackler Faculty of Medicine and the Sagol Neuroscience Center at Sheba Medical Center, Tel Hashomer, documented the exceptional creativity of Parkinson's patients two years ago in a review for Behavioral Neuroscience. Since then, she has conducted the first empirical study to verify a link between Parkinson's disease and artistic inclination. [More]
Researchers examine which teens have emotional symptoms after concussion

Researchers examine which teens have emotional symptoms after concussion

After a concussion, teens who are sensitive to light or noise may be more likely to also have emotional symptoms such as anxiety, according to a study released today that will be presented at The Sports Concussion Conference in Chicago, July 11 to 13, 2014, hosted by the American Academy of Neurology, the world's leading authority on diagnosing and managing sports concussion. [More]
Sleep problems in PD patients can worsen in later stages of disease

Sleep problems in PD patients can worsen in later stages of disease

Up to 70% of Parkinson's disease (PD) patients experience sleep problems that negatively impact their quality of life. [More]
New paper states that doctors have ethical obligation to educate, protect athletes from concussion

New paper states that doctors have ethical obligation to educate, protect athletes from concussion

The American Academy of Neurology (AAN), the largest professional association of neurologists and a leading authority on sports concussion, is releasing a new position paper that states doctors have an ethical obligation to educate and protect athletes from sports concussion and clear them to play only when the athlete is medically ready, standing firm against objections from players, parents or coaches. [More]
Parkinson's disease drug could also help people with phobias or PTSD

Parkinson's disease drug could also help people with phobias or PTSD

A drug used to treat Parkinson's disease could also help people with phobias or post-traumatic stress disorder (PTSD). Scientists of the Translational Neurosciences Research Center at Johannes Gutenberg University Mainz are currently exploring the effects of psychotherapy to extinguish fears in combination with L-dopa. [More]
New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

Alzheimer's disease, which is the most common cause of dementia, is fatal and currently, there is no cure. In Alzheimer's disease, brain cells are damaged and destroyed, leading to devastating memory loss. [More]
Cinnamon can be used to halt disease progression in Parkinson's patients

Cinnamon can be used to halt disease progression in Parkinson's patients

Neurological scientists at Rush University Medical Center have found that using cinnamon, a common food spice and flavoring material, can reverse the biomechanical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease (PD). [More]
Researchers develop new "nanojuice" to help doctors better identify human gut

Researchers develop new "nanojuice" to help doctors better identify human gut

Located deep in the human gut, the small intestine is not easy to examine. X-rays, MRIs and ultrasound images provide snapshots but each suffers limitations. Help is on the way. [More]
MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain. [More]
Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Persons with reduced levels of the TREM2 protein could be at greater risk of developing neurodegenerative diseases such as Alzheimer's disease or frontotemporal dementia, according to an international study which included the participation of the Universitat Autònoma de Barcelona and the Sant Pau Biomedical Research Institute. [More]