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Parkinson's disease is a brain disorder. It occurs when certain nerve cells (neurons) in a part of the brain called the substantia nigra die or become impaired. When approximately 80 percent of neurons are damaged, the symptoms of Parkinson's disease appear. Parkinson's disease affects 1 in 100 people over the age of 60, with the average age of onset being 60 years. The risk of developing Parkinson's disease increases with age. In the United States, it is estimated that 60,000 new cases of Parkinson's disease are diagnosed each year, with 1.5 million Americans currently living with the disease.
Dopamine replacement therapy liked with decline in depressed Parkinson patients' cognitive function

Dopamine replacement therapy liked with decline in depressed Parkinson patients' cognitive function

A group of scientists from the University of Kentucky College of Medicine and the Sanders-Brown Center on Aging has found interesting new information in a study on depression and neuropsychological function in Parkinson's disease (PD). [More]
New insight provides potential to improve treatment for sepsis

New insight provides potential to improve treatment for sepsis

In a review published in the April issue of Immunity, Kevin J. Tracey, MD, president of The Feinstein Institute for Medical Research, says it's time to take a fresh look at the medical community's approach to treating sepsis, which kills millions worldwide every year, including more than 200,000 Americans. [More]
Researchers develop new technique for discovering natural compounds that form basis of novel therapeutic drugs

Researchers develop new technique for discovering natural compounds that form basis of novel therapeutic drugs

Researchers at Griffith University's Eskitis Institute have developed a new technique for discovering natural compounds which could form the basis of novel therapeutic drugs. [More]
Apathy signals brain shrinkage in old people

Apathy signals brain shrinkage in old people

Launer's team used brain volume as a measure of accelerated brain aging. Brain volume losses occur during normal aging, but in this study, larger amounts of brain volume loss could indicate brain diseases. [More]
Study evaluates co-occurrence of cancers in patients with central nervous system disorders

Study evaluates co-occurrence of cancers in patients with central nervous system disorders

The study evaluated the co-occurrence of cancers in patients with central nervous system disorders, including Alzheimer's disease, amyotrophic lateral sclerosis, autism spectrum disorders, Down's syndrome, Huntington's disease, multiple sclerosis, Parkinson's disease and schizophrenia. [More]
Impax resubmits NDA for RYTARY providing updated safety and stability information

Impax resubmits NDA for RYTARY providing updated safety and stability information

Impax Pharmaceuticals, a division of Impax Laboratories, Inc. (NASDAQ: IPXL), announced today the resubmission of Impax's New Drug Application (NDA) for RYTARY (IPX066) to the U.S. Food and Drug Administration (FDA). [More]

ICB International develops tracer for imaging alpha-synuclein in Parkinson's disease

On March 4, 2014, ICB International, Inc., ("ICBI"), announced the development of a tracer for imaging alpha-synuclein (a-Syn) in Parkinson's-like mice at the Keystone Symposium for Parkinson disease (PD) in Keystone,Colorado. [More]
Researchers identify biological process that appears to trigger Parkinson's disease

Researchers identify biological process that appears to trigger Parkinson's disease

Working with human neurons and fruit flies, researchers at Johns Hopkins have identified and then shut down a biological process that appears to trigger a particular form of Parkinson's disease present in a large number of patients. A report on the study, in the April 10 issue of the journal Cell, could lead to new treatments for this disorder. [More]

Scientists discover potential cause of Parkinson’s disease

Researchers have discovered a process that appears to explain how a well known enzyme mutation triggers the neural deterioration seen in Parkinson’s disease. [More]

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

A research led by the Research Institute Vall d'Hebron (VHIR), in which the University of Valencia participated, has shown that pathological forms of the α-synuclein protein present in deceased patients with Parkinson's disease are able to initiate and spread in mice and primates the neurodegenerative process that typifies this disease. [More]
Older people with memory and thinking problems may have lower risk of dying from cancer

Older people with memory and thinking problems may have lower risk of dying from cancer

Older people who are starting to have memory and thinking problems, but do not yet have dementia may have a lower risk of dying from cancer than people who have no memory and thinking problems, according to a study published in the April 9, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Medison Pharma inks agreement with Brainsway for exclusive marketing of Deep TMS system in Israel

Medison Pharma inks agreement with Brainsway for exclusive marketing of Deep TMS system in Israel

Medison Pharma has concluded an agreement with the medical device company Brainsway for exclusive marketing and distribution of the Deep TMS (Transcranial Magnetic Stimulation) system in Israel. [More]
Scientists work together to get a better understanding of Parkinson's disease

Scientists work together to get a better understanding of Parkinson's disease

Each day, 80 people are newly diagnosed with Parkinson's disease (PD) in the UK and one in 20 will be under the age of 40. [More]

Researchers develop computational model of part of brain responsible for motor decision-making

Talking or reading. Texting a message or listening. The dilemma of choosing between various tasks is not an invention of the modern information age. Humans and all vertebrates have to prioritise their actions. [More]

Findings confirm importance of brain activity during sleep for memory strength and accuracy

The sense of smell might seem intuitive, almost something you take for granted. But researchers from NYU Langone Medical Center have found that memory of specific odors depends on the ability of the brain to learn, process and recall accurately and effectively during slow-wave sleep — a deep sleep characterized by slow brain waves. [More]

Professor receives $1.7M NIH grant to explore novel treatments for chronic methamphetamine users

A Wayne State University professor recently received a nearly $1.7 million grant from the National Institutes of Drug Abuse of the National Institutes of Health to explore whether proteasome and parkin — two components of the ubiquitin-proteasome system — are potential pharmaceutical drug targets that can be manipulated to promote survival and recovery of dopaminergic terminals after binge and chronic administration of toxic doses of methamphetamine. [More]
Researchers use ultrasound to destroy cancerous tissue in brain

Researchers use ultrasound to destroy cancerous tissue in brain

Researchers in Zurich, Switzerland have successfully used focused ultrasound for the first time to non-invasively ablate part of a recurrent glioma tumor through a patient's intact skull. [More]
UCSF/Daiichi Sankyo establish drug-discovery collaboration focused on neurodegenerative diseases

UCSF/Daiichi Sankyo establish drug-discovery collaboration focused on neurodegenerative diseases

Daiichi Sankyo Co., Ltd. (hereafter, Daiichi Sankyo) and UC San Francisco (UCSF) announced today that they have established a drug-discovery collaboration focused on developing novel therapeutics and molecular diagnostics for multiple neurodegenerative diseases. [More]

Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

Young adults who run or participate in other cardio fitness activities may preserve their memory and thinking skills in middle age, according to a new study published in the April 2, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. Middle age was defined as ages 43 to 55. [More]

San Diego research team studies brain dynamics of motor control

A University of California, San Diego research team led by bioengineer Gert Cauwenberghs is working to understand how the brain circuitry controls how we move. The goal is to develop new technologies to help patients with Parkinson's disease and other debilitating medical conditions navigate the world on their own. [More]